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Prenatal Stress Keeps Infants, Toddlers up at Night, Study Says

...t these patterns may be set early on, perhaps even before birth, said lead author Thomas OConnor, Ph.D., associate professor of Psychiatry at the University of Rochester Medical Center. This is another piece in the unfolding mystery of just how much the prenatal environment may shape a childs health and dev...

Genomic Analysis Uncovers New Targets for HIV Vaccine

... tests documenting viral loads after infection and before they started receiving antiretroviral treatment. The three polymorphisms were identified after all the blood samples of the selected patients were screened for more than 555,000. Additionally, the researchers discovered many other genetic variants ...

Scratch no more: Gene for itch sensation discovered

...provide a compelling link between GRPR and itching before now. "Scientists have been studying this receptor for more than a decade," Chen says. "One interesting thing they've found is that GRPR is implicated in tumor growth. As a result of research like this, a lot of substances have been made that block th...

FDA sees nanotech challenges in every product category it regulates

...n necessary to ensure the safety of novel products before they enter the market, and to detect and move swiftly to correct any problems that may arise. Given the agency’s insufficient resources—which for two decades have not kept pace with inflation—making sure that FDA has the capacity to safely manage nan...

Researchers discover inherited mutation for leukemia

...1, which normally helps trigger the death of cells before they become cancerous. Researchers identified the mutation by testing a family in which the father, four sons, a grandson and a distant female relative developed this form of leukemia. The chemical change is called DNA methylation. Healthy cells ...

Agent slows aging in mice

...e results in animals. Much more research is needed before any possible human anti-aging drug could emerge, Miller says. “Even if this agent turns out to be good for mice, it won’t be possible to tell without careful studies of humans whether NDGA is beneficial, useless, or harmful to people. Occasional...

Blood test may help signal tumor's remission, return in throat cancer patients

...t for advanced throat cancer. Starting immediately before treatment and continuing every three months for 12 months, the researchers tested the patients’ blood for five proteins that, in previous studies, had been found to occur at heightened levels in head and neck cancer patients. These include two cytoki...

Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes

...archers measured the level of HBV DNA in the blood before the start of chemotherapy. They also gathered other potentially important prognostic information, like age, sex, total bilirubin and presence of cirrhosis. Over the course of each patient’s treatment, the researchers monitored blood counts, renal and...

Cigarette smoke alters DNA in sperm, genetic damage could pass to offspring

...that fathers can potentially damage offspring long before they may even meet their future mate.” Males, whether they are mouse or man, generate a constant supply of new sperm from self-renewing spermatogonial stem cells. Yauk, along with colleagues at Health Canada and McMaster University, studied the...

Simulations unravel outer membrane transport mechanism

...look at the accessibility of certain (amino acids) before and after activation,” Tajkhorshid said. “And sometimes the labeling agent that they use diffuses into the beta-barrel and labels the inside: You don’t know whether what you have labeled is happening inside or outside.” U. of I. researchers simulat...

Crammed with charged DNA, pressure rises inside virus

...ould be an artist’s depiction of someone’s stomach before and after a rather decadent meal. But it is a 3-D...pe reconstruction of the cross-section of a virus, before and after cramming itself full of its own DNA. The virus, phi29, has a tiny motor that pumps its DN...

Snoring in children might be an allergic type disease

... a group of children who have been monitored since before they were born. “Our findings were consistent with the view that snoring forms part of the spectrum of allergic diseases in childhood,” he said. While the study findings are limited to children with rhinitis, Dr Marshall explained the observed ...

Research team identifies new Alzheimer's gene

...ple with and without Alzheimer’s disease than ever before has enabled researchers to identify a common gene ... our ability to diagnose Alzheimer’s disease, even before it strikes” To date, the most significant gene found to predispose an individual to late onset Al...

Loss of stem cells correlates with premature aging in animal study

... tissue maintenance, and so, they subsequently age before their time.” With this new knowledge of how DNA repair, stem cells, and the aging process interconnect, Brown, first author Yaroslava Ruzankina, and Amma Asare are currently using this mouse model to discover compounds that preserve stem cells and...

New bacterium discovered -- related to cause of trench fever

...e was infected with a new bacterium that had never before been isolated from a human. A UCSF infectious disease team, in collaboration with colleagues from other institutions, found that the new microbe is genetically similar to one spread by body lice in the trenches during World War I. That bacterium...

Studies to find better ways to preserve human eggs, ovarian tissue under way

...otect cells from the hazards of freezing are added before taking tissue from the refrigerator temperature of 4 degrees Celsius to minus 80 degrees Celsius over two- and one-half hours. Later, liquid nitrogen takes it to minus 196 degrees “You put it in a control-rate freezer that takes down the temperatu...

Longer treatment benefits sleep apnea patients

... for daytime functioning using a standardized test before treatment and after three months of CPAP therapy. The findings suggest that most patients should use CPAP for at least 7.5 hours each night to realize the greatest possible benefits of therapy. "Relationship Between Hours of CPAP Use and Achievi...

Ancient DNA traces the woolly mammoth's disappearance

...rian mammoths expanded from a small base some time before sixty thousand years ago. Moreover, they found two...t mammoths had diverged in isolation for some time before merging back into a single population. The DNA further suggests that no later than forty thousand ye...

Brightening prospects of using fluorescent nanotubes in medical applications

...within a few hours. Quantum dots last several days before degrading. Hertel’s team is currently working on the next step necessary for many biomedical uses: finding a way to attach molecules to the surface of the nanotubes that will allow them to bind to specific biological targets. The trick is to do so...

Sun exposure early in life linked to specific skin cancer gene mutation

... more likely to report high levels of sun exposure before age 20. People with the NRAS mutation were more likely to have had high exposure between the ages of 50 and 60. About 15 percent of melanomas contain the NRAS mutation. The findings come from the initial phase of an ongoing study that will ultimat...

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