The secret to longevity in tubeworms
... form of sulfide - to keep going for this long has been a mystery. In a paper just published in the premier open-access online journal PLoS Biology, Erik Cordes and colleagues now provide a solution: by releasing its waste sulfate not up into the ocean but down into the sediments, L. luymesi stimulates th...Another Look Finds Promising Proteomics Test is Not Biologically Plausible
...e of this emerging field of proteomics has not yet been met due to the difficulty in finding complex, reproducible patterns of proteins. According to Baggerly, that now appears to be the case with the experimental ovarian cancer test at issue, which was first proposed in 2002 by researchers in the journa...Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering
...Over thepast ten years more than 3,000 papers have been published usingGeneChip technology. For more information, please visitwww.Affymetrix.com.......e of this emerging field of proteomics has not yet been met due to the difficulty in finding complex, reproducible patterns of proteins. According to Baggerly, that now appears to be the case with the experimental ovarian cancer test at issue, which was first proposed in 2002 by researchers in the journa...Cracking the olfactory code in bees
...e of this emerging field of proteomics has not yet been met due to the difficulty in finding complex, reproducible patterns of proteins. According to Baggerly, that now appears to be the case with the experimental ovarian cancer test at issue, which was first proposed in 2002 by researchers in the journa...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
...Technology Branch.Gene expression microarrays have been used in numerous applications,including identifyin...nt outcome. So far, though,microarray studies have been performed by individual institutions.Evaluation of the potential clinical use of microarrays may req...Signaling protein builds bigger, better bones in mice
...e of this emerging field of proteomics has not yet been met due to the difficulty in finding complex, reproducible patterns of proteins. According to Baggerly, that now appears to be the case with the experimental ovarian cancer test at issue, which was first proposed in 2002 by researchers in the journa...Computers to be used to find blueprint for new influenza drug
...time the software, developed in Germany, will have been used in Britain. It will allow accurate modelling of the behaviour of tens of thousands of atoms, many times more sophisticated than previous work. “Developing a blueprint for a new way of fighting influenza is a very important task," said Professor...Ecological destruction fuels emerging diseases
...arch Canada (NSERC). "In the past, when there have been episodes of major climate change or mass extinctio...their areas of origin into other areas, there have been emerging diseases. Parasites have moved into new areas and they've jumped ship into new hosts." He ...A much-needed shot in the arm for HIV vaccine development
...rds developing avaccine against HIV infection have been given a much-needed boost bythe publication today of the Global HIV/AIDS Vaccine Enterprise'sscientific strategic plan, published online in the freely available,open-access global health journal PLoS Medicine.The Global HIV/AIDS Vaccine Enterprise is...Newly discovered virus linked to childhood lung disorders and Kawasaki disease
...which infect animals. In humans,coronaviruses have been known primarily for causing colds or, morerecently, severe acute respiratory syndrome (SARS). Genetic evidencenow suggests that a previously unknown coronavirus may account for someof the many respiratory diseases for which a causative agent isuniden...Ancient olfaction protein is shared by many bugs, offering new pest control target
...red, arguing not only that the gene's sequence has been conserved over 250 million years of evolution but that the gene's function in olfaction has also been conserved. Future designs of pesticides and disease-controlling insect repellents may be able to uti...New Technique for Tracking Gene Regulators
...al, and the function of nerve cells. But there has been no easyway to screen the entire genome. “We are th... do a genome-widesurvey,?says Dunn.The problem has been the sheer magnitude of information in the genome:three billion nucleotides, and many tens of thousan...Bacteria collection sheds light on urinary tract infections
...om the Gastroenteric Disease Center, it would have been difficult for the researchers to carry out the res...ng to DebRoy. The Gastroenteric Disease Center has been collecting E.coli samples since 1965 and is the largest repository of E.coli in North America. The c...Bound for destruction: Ubiquitination protects against improper Notch signaling
...s the question of how Notchreceptors that have not been activated by a ligand are protected fromdigestion ...eins marked for degradation), as it had previously been shownthat Nedd4 plays a role in the processing of other types oftransmembrane proteins. Proteins in ...Combination therapy boosts effectiveness of telomere-directed cancer cell death
...g. Telomerase is not used by healthy cells, andhas been identified as a logical target for anticancer therapeutics.However, recent studies indicate that for this therapy to be effective,telomeres must be in a critically short state, requiring an extendedtreatment duration that can lead to drug resistance ...GATA: a graphic alignment tool for comparative sequence analysis
...g. Telomerase is not used by healthy cells, andhas been identified as a logical target for anticancer therapeutics.However, recent studies indicate that for this therapy to be effective,telomeres must be in a critically short state, requiring an extendedtreatment duration that can lead to drug resistance ...Research on Worms Yields Clues on Aging
Humanityhas been looking for a "Fontaine de Jouvence" forever; a way to slow orstop aging. While its still nowhere to be found, we are makingprogress; in worms. Researchers found that an epilepsy drug used inhumans had the unexpected effect of prolonging the life spa...Imaging Lymph Nodes with Nanoparticles
... this workup is assessing whether or not there has been lymphatic spread. Currentmethods include surgical ...a differently.And what is more, once the data have been collected and assessed it ispossible to reconstruct a virtual picture of the patient's lymph nodes,t...... reach the muscle. Until now,researchers have only been able to investigate nerve regeneration inmice and zebrafish, which have complex nervous systems. This laserallows researchers to study nerve cells at their most basicevolutionary form, opening the door to other experiments on genetic andmolecular fac...