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Bioartificial kidney under study at MCG

...ischemic and begin to fail if blood pressure drops because of a long surgery with significant blood loss. Infection can further reduce blood flow to the kidneys. Ironically, some antibiotics patients need for these infections also can harm the kidneys. Even the contrast medium needed to study kidney function...

Wisconsin scientists grow critical nerve cells

...the University of Wisconsin-Madison, are important because they provide critical guideposts for scientists trying to repair damaged or diseased nervous systems. Motor neurons transmit messages from the brain and spinal cord, dictating almost every movement in the body from the wiggling of a toe to the roll...

Man and mouse share genome structures

...lls are different from neurons. They are different because different genes are on." Many scientists believe ...k these sites have important regulatory functions, because the methylation patterns are similar in comparable portions of the mouse genome. Until now, they'd b...

Molecular biology fills gaps in knowledge of bat evolution

... yet their evolutionary history is largely unknown because of a limited fossil record and conflicting or inco... For Springer, this latest research is significant because it shows that molecular information can contribute to resolving and illuminating long-standing probl...

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...l of interest in the microbes of the Earth's crust because the strategies by which they survive may be similar to the earliest strategies of life on Earth, and perhaps also on other planetary bodies," said Rachel M. Haymon, UCSB professor of geology. Newly discovered geological and biological manifestations...

W.M. Keck Foundation funds study of friendly microbes

... 99 percent of the genes in the adult body. That's because it didn't sequence genes belonging to the vast com...ities, in health and in disease, has been hampered because the majority of gut bacteria are difficult or impossible to grow and study outside of the intestine....

Yellowstone microbes fueled by hydrogen, according to U. of Colorado study

... is also interesting inthe context of microbiology because it's one of the few times we'vebeen able to study ...concentration ofhydrogen in the hot springs before because the technology didn't existuntil about seven years ago. Now we can detect very low-levelconcentratio...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

... researchers' mice mirror two situations in people because the double dose of IGF2 was accomplished in two wa... Tilghman at Princeton, have a double dose of IGF2 because they are missing another gene, H19, whose sequence overlaps the region that usually shuts off one co...

Columbia research lifts major hurdle to gene therapy for cancer

... brain (glioma), skin(melanoma) and colon cancer - because the virus is constructed toexploit a characteristic of all solid cancers."What's exciting is we may now be able to design a therapy that willseek out and destroy only cancer cells," said the study's seniorauthor, Paul B. Fisher, Ph.D., professor of c...

Topical treatment shown to inhibit HIV and herpes simplex virus infection

...smitted infections, their effectiveness is limited because they require partner initiation or consent." According to the United Nations' 2004 report on the global AIDS epidemic, an estimated 40 million people worldwide are living with HIV, and women account for nearly half of those infected. As stated by th...

Priming embryonic stem cells to fulfill their promise

...h combinatorial assays for otherdesired cell types because they have no practical way to do so. Bhatia,Chien, and Flaim seized on the unique ability of so-called DNA spottingmachines to deliver tiny volumes of liquid, about one trillionth of aliter per spot. The spotting machines, which cost as little as $20...

Growth in the sea comes down to a struggle for iron

... other areas have a persistent excess of nutrients because phytoplankton growth is reduced." Many scientists...sscrossing transects to re-do the map of the patch because of this rapid change," says Wells. The two vessels worked together in the patch for 12 days but ope...

New, automated tool successfully classifies and relates proteins in unprecedented way

... cancer growth."Our tool represents a step forward because it is based on standardizedfeatures and not on features chosen by the human eye, which isunreliable. By automating the clustering of proteins inside cellimages, we also can study thousands of images fast, objectively andwithout error," Murphy said.Mu...

Lack of enzyme turns fat cells into fat burners

...ter) fat, and passingit on to the heart and muscle because there is an increase in oxidationof fat in those organs. It also starts oxidizing glucose. In otherwords, the adipose tissue is becoming a little more oxidative and lessinvolved in the synthesis and storage of fat. We feel this contributesto the stat...

Fox Chase Cancer Center scientists identify immune-system mutation

...t, according to Kappes. Helper T cells, so called because they arise from the thymus gland, are essential fo... the body. Other T cells are known as killer cells because they attack foreign invaders more directly. "The maturation of T cells involves key branch points a...

Controversial drug shown to act on brain protein to cut alcohol use

...period ofabstinence was an exciting finding for us because this is the type ofbehavior in alcoholics for which very few effective drugs exist," Janaksaid.The scientists confirmed in a cell model that Ibogaine stimulated GDNFactivity. Finally, they showed that a known inhibitor of GDNF blockedIbogaine's abili...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...mmercially availableserum replacements, apparently because these are also derived fromanimal products," said ...tic tool in humans."It's an important safety issue because this opens up the idea thatmetabolic transfer of glycans is occurring between cells," said Gage."Als...

UCLA Study Shows One-Third of Drug Ads in Medical Journals Do Not Contain References Supporting Medical Claims

...ion would not be provided due to company policy or because it was proprietary. "We found that almost one-third of the pharmaceutical ads offered no references at all to support medical claims. In addition, most of the data-on-file documents in support of the medical claims were not available from the drug c...

Anti-bacterial additive widespread in U.S. waterways

...emical thathas been studied in much greater detail because it is more easilydetectable.Using an empirical model and published data on the environmentaloccurrence of triclosan, the researchers predicted triclocarbanconcentrations for 85 U.S. streams. The study results suggest that theantimicrobial contaminant...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

... call this dual function a "biological capacitor," because Pax3 tells the cell: Get ready to go, but at the same time won't let it proceed." Pangenes Express Behavioral Qualities of Pan and Peter Pan Epstein notes that this research is conceptually new since he suggests that a single gene can both tell a c...

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