Pair of studies offer new clues to combat antibiotic resistance
In the continuing battle against antibiotic resistance, two new studies shed light on the complex defense mechanisms pathogenic bacteria use to evade antibiotic attack, an understanding of which could lead to new, more effective antibiotics to help save lives and combat the ...Newly identified mechanism helps explain why people of African descent are more vulnerable to TB
...ferent way to think about how human immune systems battle pathogens in general. The research team found that when Toll-like receptors in humans are stimulated by specific molecules of the tubercle bacillus, vitamin D receptors and an enzyme called Cyp27B1, which converts the vitamin from an inactive form t...A large step forward in the fight against African sleeping sickness
...e University of Brussels are making strides in the battle against this disease. They have coupled the human protein ApoL-1 with a nanobody in order to very specifically eliminate the infection caused by the pathogenic parasites, against which our defense mechanism is powerless. Tests on mice are already p...A step forward in the fight against bacterial infections
...acterial infections. Another step forward in the battle against bacterial infections The results of this research are very relevant to the quest for new therapeutics for bacterial infections. The mutant mice display a combination of important characteristics: they are resistant to LPS, but they still re...UC Davis study finds HIV hiding from drugs in gut, preventing immune recovery
...System and senior author of the study. "The real battle between the virus and exposed individuals is happening in the gut immediately after viral infection," she said. "We need to be focusing our efforts on improving treatment of gut mucosa, where massive destruction of immune cells is occurring. Gut-asso...Stanford snake venom study shows that certain cells may eliminate poison
...ith the venom," said Galli. But Galli called the battle between predators with venom and their prey "a kind of evolutionary arms race." He and Metz suspect that, given the broad range of venoms that have been developed by snakes and other creatures, mast cells probably won't perform as well against every ...DNA: Bacteria's survival ration
...y, finds that DNA is a critical food source in the battle of the fittest. Bacteria that stay alive just a little longer than their counterparts get a double reward: the competition for food lessens, and the supply of nutrients increases. "The bacteria actually eat the DNA, and not only that, they can use t...RNA interference stops colon cancer spread in mice
... researchers have scored a dramatic success in the battle against colorectal cancer. The scientists were the first to use what are known as "small interfering RNAs" to block the spread of human colorectal cancer cells implanted in laboratory mice. Small interfering RNAs (siRNAs), first described in 2001, a...How HIV 'exhausts' killer T cells
...f a viral attack. "It may be that in the heat of a battle that it sees it's not winning, the body makes an adjustment to try to co-exist," he said. "But we really do not know at this point." Walker emphasized that the study could not have been done without his group's ongoing collaboration with the U...A new tool against brain disease
...f a viral attack. "It may be that in the heat of a battle that it sees it's not winning, the body makes an adjustment to try to co-exist," he said. "But we really do not know at this point." Walker emphasized that the study could not have been done without his group's ongoing collaboration with the U...T cells activated to fight HIV basis for dendritic cell therapeutic vaccine
...y version of boot camp may help patients win their battle against HIV, believe University of Pittsburgh researchers. In essence, that's the concept behind the development of a novel therapeutic vaccine loaded with a patient's own souped up dendritic cells, which have been galvanized to rally other cells of ...Pollen proves beneficial for northern lakes
...n to most people and it triggers thoughts of their battle against allergic reactions. However, a University of Alberta researcher has found an important spin-off for this fine yellow dust-like powder. Mark Graham, a PhD student from the Department of Biological Sciences at the U of A, has shown for the f...Nice guys do finish first in lizards' evolutionary race
...s and have a buddy system. One blue-throat will do battle with the orange-throat, enabling his buddy stay fit and mate. McAdam explains that the altruistic blue-throat does this, even though as a result he will sire few, if any, offspring. The yellow-throated lizards are sneakers ?they casually sneak into...Combination therapy shows promising results in patients with advanced lung cancer
...rceva with Celebrex, a COX-2 inhibitor, would help battle resistance and prove to be an affective combination against lung cancer. Typically, about 10 percent of lung cancer patients respond to Tarceva. In Reckamp's study of the combination therapy, about 33 percent of patients responded. "Tarceva alone i...Pure carbon nanotubes pass first in vivo test
...y last day, he was simultaneously fighting his own battle with cancer and developing new ways to treat the disease that ultimately took his life. These new results are simply the first fruits of his final contributions in nanohealth research, and there are still more to come." ...Experimental vaccine protects mice against deadly 1918 flu virus
... white blood cells critical in the immune system's battle against invading viruses, as well as the production of neutralizing antibodies. To determine the vaccine's protective effects, the CDC's Dr. Tumpey intranasally exposed a group of mice to live, reconstructed 1918 virus 14 days after they were immu...Nano-devices hold promise for early-stage cancer detection
... "This research is opening up a new front in the battle against cancer and other diseases," said Jamal Deen, the lead applicant, professor of electrical and computer engineering and Canada Research Chair in Information Technology, McMaster University. "The technology zeros in on specific malignant cells ...Extreme environment changes fish appearance
...6, the inch-long fish was at the center of a legal battle that reached the U.S. Supreme Court. Conservationists had established the fish in refuges elsewhere in case Devil's Hole became too dry. But the refuge-bred fish began to look different, with deeper bodies and smaller heads, although all the fish are...Did 'ABCs' cause Uganda's fall in HIV rates?
... of whether the ABCs are helpful or harmful in the battle to control the HIV pandemic. Elaine Murphy and Margaret Green (George Washington University School of Public Health and Health Services) argue that "ABC behaviors were attainable in Uganda" and the promotion of ABC messages was "exceptionally succes...Napoleon's mysterious death unmasked, UT Southwestern researcher says
...h of Europe, but he was ultimately defeated at the battle of Waterloo in 1815. The British then exiled him to St. Helena, an island in the South Atlantic Ocean. He died May 5, 1821. The cause of his death has been highly scrutinized over the years. Dr. Genta and his colleagues, whose research focuses ...