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Tag: "base" at biology news

Unexpressed But Indispensable -- The DNA Sequences That Control Development

...ements (CNEs), with an average length of about 200 base pairs. The average sequence match is 84%: not perfect, but much higher than for coding regions shared by humans and pufferfish. A quick check showed that virtually all the sequences also occurred in rodents, chickens, and zebrafish, but not in the ne...

Discovery Could Lead To Novel Approaches In HIV Treatment

...assess how well the thymus (an organlocated at the base of the neck) works and the discovery of afunctional abnormality of this organ in HIV-infected individuals. Theteam of investigators led by Dr. Rafick-Pierre Sékaly, professor atUniversité de Montréal, scientist at the CHUM Research Centre, andScienti...

Scientists develop new color-coded test for protein folding

...odies and other disease-related proteins. Acid and base In their experiment, Zare, postdoctoral fellow Soonwoo Chah and graduate student Matthew R. Hammond created a liquid solution containing nano-sized particles of gold saturated with a protein called cytochrome c. "We chose gold nanoparticles because...

New Study from Affymetrix Laboratories Points to Changing View of How Genome Works

...cleus had not been previously detected. Any single base in the genome can be transcribed into several different transcripts with different, but overlapping sequences. Often, transcripts from one strand of DNA can share parts of their sequence with overlapping transcripts from the same strand or even from ...

A bacterial genome reveals new targets to combat infectious disease

...is Wolbachia genome is small, only about a million base pairs, and many metabolically critical genes have degraded through mutation to the point of uselessness. This phenomenon, called reductive evolution, is typical of long-term symbioses, as the two partners increasingly complement one another's biochem...

Color-blind method opens new doors in DNA sequencing

...me consists of a unique ordering of some 3 billion base pairs, and 'DNA sequencing' refers to the process scientists use to read out the order of those nucleotides. In sequencing, scientists first extract DNA from the nuclei of cells and through a painstaking series of bacterial cloning and/or polymerase...

Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa

...rong research component and an established patient base of degenerative retinal diseases, we were able to be a part of this important study." Pre- and post-surgery patients are evaluated by a team of researchers working at the Eye Center and the VA Rehabilitation R&D Center including Ronald A. Schuch...

New Technique for Tracking Gene Regulators

...tion?enzyme that recognizes aparticular nucleotide base sequence, CATG. Further manipulation of thecut ends allows them to isolate 20-base-long-fragments, or “tags,?ineach direction from these cut sites. This gives the scientists a largenumber of very short DNA “tag?sequences, which all have the same star...

Novel technology detects human DNA mutations

...requires sifting through the more than one billion base pairs of DNA to find a particular base pair of interest. Once that base pair is located, it is then necessary to determine if either of the...

Man and mouse share genome structures

...we see huge stretches of genome, many thousands of base pairs in length, that are completely covered by tags." The researchers speculate that these unique chromatin structures could be activating sets of HOX genes for specific developmental programs. This global activation may have implications for under...

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