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Vitamin A's paradoxical role in influencing symmetry during embryonic development revealed

...cription of retinoic acid signaling in the uniform ball of cells that is the early embryo, because its signaling influences both the asymmetric arrangement of organs and tissues in the interior of our bodies and the symmetrical pattern of the exterior of the trunk. Belmonte and his Salk colleagues evalua...

Can't serve an ace? Could be muscle fatigue

...required to maintain the best position, to get the ball where it needs to go. "However, if the limbs are fatigued the brain must activate them harder and this leads to errors about where the different body parts are located." Professor Proske said the research could also offer insight into the symptoms ...

Chemical 'band-aid' prevents heart failure in mice with muscular dystrophy

...ction, which causes the cell to roll into a little ball and die." To test for the presence of tears in myocyte membranes, U-M researchers used a special fluorescent dye, which cannot penetrate an intact cell membrane. After a 20 percent stretch, control myocytes remained stable and showed no fluorescence...

Computers close in on protein structure prediction

...ns collapse into their lowest energy state, like a ball that rolls down a hill until it comes to rest on level ground. The energies of hundreds of thousands of possible shapes generated by the computer are computed, and the lowest energy shape is selected as the prediction. The prediction process happens...

North & South American researchers find architectural abnormalities in T. cruzi ribosome

...site's ribosome. A ribosome is basically a double ball made mostly of RNA and over 50 proteins. The balls, which are of unequal size, are called small and large subunits. After a string of messenger RNA (mRNA) copies the information encoded on a gene, it enters a sea of ribosomes, where that genetic info...

Scientists unpick genetics of first 15 minutes of life

...pro-nucleus in s�same mutant is wound into a tight ball that could not interact with its female counterpart, the egg pro-nucleus. This showed that there was a problem with the re-packaging process in the s�same mutant. The researchers looked at the genetic makeup of the s�same mutant and identified what...

Grabbing addiction by the tail

...n to drugs, cells in the nucleus accumbens ?a tiny ball of tissue deep in the brain involved in pleasure and motivation ?mis-communicate. Normally, one neuron triggers activity in a neighbor by using neurotransmitters such as glutamate. "This is the 'go' signal," said Wang. "The receiving cell uses gluta...

With few factors, adult cells take on character of embryonic stem cells

...ed from inner cells of the mammalian blastocyst, a ball of cells that develops after fertilization and goes on to form a developing embryo. Cells from other parts of the body can also be "reprogrammed" by transferring their nuclear contents into egg cell precursors called oocytes or by fusion with embryon...

Magnetism and mimicry of nature hold hope for better medicine, environmental safety

...ter and biological fluids typically bead up like a ball on superhydrophobic surfaces, but the introduction...iny magnetic particles into the droplets keeps the ball from rolling off the surface. This allows for the fluids to be controlled through exerting magneti...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

...nd spread and rolled it into a liposome -- a lipid ball so small that its dimensions are measured in nanometers (billionths of a meter). Getting the siRNA inside tumor cells is important, Sood said, because the targeted protein, focal adhesion kinase (FAK), is inside the cell, rather than on the cell s...

With few factors, adult cells take on character of embryonic stem cells

...ed from inner cells of the mammalian blastocyst, a ball of cells that develops after fertilization and goes on to form a developing embryo. Cells from other parts of the body can also be "reprogrammed" by transferring their nuclear contents into egg cell precursors called oocytes or by fusion with embryon...

Using brain scans, researchers find evidence for a two-stage model of human perceptual learning

...ary. For example, a green apple and a green tennis ball are both green and round, but only an apple can be eaten and only a green tennis ball belongs to a sport. In this study, the research team asked human volunteers to undertake a serie...

Robotic therapy helps restore hand use after stroke

...nking glass, pinching to pick up a small marble or ball bearing, and putting your hand on your head -- improved by nearly 10 percent. And their average score rose by nearly 20 percent on the Box-and-Blocks Test, which assesses manual dexterity as one moves blocks from one side of a box to another in one m...

Nanotechnology meets biology and DNA finds its groove

...e, is a twisted knot, looking more like a battered ball of yarn than the famous double helix. To study it, scientists generally are forced to work with collections of molecules floating in solution, and there is no easy way to precisely single out individual molecules for study. Now, however, scientist...

Does amateur boxing cause brain damage?

...e study was extended to soccer players heading the ball repeatedly from long and high goal kicks. No increased levels of biochemical markers for brain damage in cerebrospinal fluid were found. "This data shows headings in soccer is not associated with any neurochemical evidence of brain damage," said Hiet...

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