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Tag: "backup" at biology news

Cells re-energize to come back from the brink of death

...n suicide pathway called apoptosis can also foil a backup self-destruct program, which allows them to surviv...hat disrupts a cancer cell’s ability to block this backup program would allow that program to kill the cell. Such a specifically targeted drug might be more e...

Scientists discover new, readily available source of stem cells

...report describes how the cells were harvested from backup amniotic fluid specimens obtained for amniocentesis, a procedure that examines cells in this fluid for prenatal diagnosis of certain genetic disorders. Similar stem cells were isolated from "afterbirth," the placenta and other membranes that are expe...

When smell cells fail they call in stem cell reserves

Hopkins researchers have identified a backup supply of stem cells that can repair the most severe damage to the nerves responsible for our sense of smell. These reservists normally lie around and do nothing, but when neighboring cells die, the scientists say, the stem cells jump into action. A ...

A new target for painkillers

...eat all pain, so having a new way is like having a backup catcher if the first catcher misses the ball." How the Study was Performed The toxins in the study come from two cone snail species that eat worms, unlike relatives that eat fish or snails and occasionally deliver a fatal sting to a human fish...

Life and death in the hippocampus: what young neurons need to survive

..., indicating that new neurons are more than just a backup supply but actually enhance learning. "Remarkably, new neurons are born in the hippocampus, a structure whose function is to acquire new information," says Gage. "That suggests that new cells are involved in how we learn." This ongoing struggle ...

DNA: Bacteria's survival ration

...ttom up. Nevertheless, Finkel said, DNA remains a backup nutrient for bacteria, being harder to digest than glucose and other simpler food sources. ...

Mice lacking key immune component still control chronic viral infections

...plex (MHC) Class Ia, has a previously unrecognized backup that is similar enough to step in and fill the void left by its absence. If so, that backup may become a new focus for efforts to design antiviral vaccines. "This surprising finding contradi...

New potential drug target in tuberculosis

...way. Unlike other organisms M. tuberculosis has no backup mechanism that could take over LipB's role. This means that an inhibitor blocking its active site would shut down key processes the bacterium needs to survive and replicate. This would be a very effective strategy for a drug." The scientists will no...

Bacteria that cause tooth decay able to survive without important biochemical pathway

... resulting from their own metabolism, suggesting a backup pathway was in place. But, like goldfish dropped in new water, the altered bacteria could not contend with sudden environmental change. When artificially shocked with acid to a pH below that where tooth demineralization begins, the altered bacteria...

Compound from marine bacteria shows potential as multiple myeloma therapy

.... With their proteasome jammed, cells die from the backup of damaged proteins. "Proteasome inhibition is a key therapeutic target and bortezomib (Velcade tm) was the first in a new class of compounds in multiple myeloma. NPI-0052 is a novel proteasome inhibitor with a chemical structure and action that is...

The shape of things to come: Morphology database going global

...g the images on several machines ensures there are backup copies and can reduce both the amount of disk space on each machine and the cost to any one institution. Although scientists will be the only ones to have access to the system to deposit, retrieve or comment on items, the system is free and may be v...

Researcher at UGA College of Veterinary Medicine identifies new way of combating viral diseases

...ody, Hodge added, because human cells tend to have backup systems that can compensate. ...

Cancer related gene p53 not regulated as indicated by previous tissue culture research

...too severe for the breaks to be repaired, critical backup protection, also governed by the p53 tumor suppressor protein, kicks in. It initiates the process of programmed cell death, or apoptosis, which directs the cell to commit suicide, permanently removing the damaged DNA from the organism. Since the p53...

DuPont's first biologically derived polymer receives global recognition

...s. Crops and plants are becoming the most reliable backup power for the resource consumption of humans and will serve to further protect the environment." DuPontTM Sorona® offers unique properties to consumers and manufacturers. Consumers appreciate the unique qualities that DuPontTM Sorona® brings to fabr...

Highly adaptable genome in gut bacterium key to intestinal health

...don says. "Mucus represents a consistent source of backup food in the intestinal environment. B. theta's adaptive foraging behavior benefits the bacterium and presumably helps maintain the stability of the microbial society that it is an integral part of." The dietary switch also caused B. theta to change ...

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