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Tag: "attractive" at biology news

Attacking cancer's sweet tooth is effective strategy against tumors

...he prospect of anti-glycolytic therapies even more attractive is their potential safety. Healthy cells meet 90 percent of their energy needs through OXPHOS. People who lack the LDHA enzyme appear to function normally though they cannot be pushed toward anaerobic exercise. "They have muscle destruction because t...

New protein target may advance design of HIV and cancer drugs

...efore, novel biological processes and proteins are attractive targets for antiviral drug development," said lead author Nicholas Farrell, Ph.D., professor and chair in the Department of Chemistry at VCU and a member scientist with the VCU Massey Cancer Center. According to Farrell, these study findings may al...

Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection

...rm protection ?all of which would make this a very attractive therapeutic option." In the animal study, bone marrow-derived neural stem-like cells (BM-NSC) genetically engineered to produce IL-23 were injected into intracranial gliomas and other areas of the brain. Treated animals survived significantly longer...

Weighting cancer drugs to make them hit tumors harder

...aid Chilkoti. "Macromolecular drug carriers are an attractive drug delivery system, because they target tumors and have limited toxicity in normal tissues." Of additional benefit, macromolecular drug carriers can be substituted for the toxic substances routinely mixed with chemotherapy to make it more soluble....

p53, tumor suppression and aging

...n. Mdm2 is a key inhibitor of p53 and therefore an attractive target to modulate p53 activity in cells. However, conflicting evidence exists regarding whether or not p53-mediated tumor suppression comes at the cost of accelerated aging. To analyze the effects of reduced Mdm2 levels on tumorigenesis ?as well as...

Chemical signaling helps regulate sensory map formation in the brain

...ay. "A repulsive Wnt-Ryk pathway competes with an attractive Wnt-Frizzled interaction," the authors write, "to titrate the response to Wnt3 protein at different concentrations." The net outcome of the competition, they conclude, "determines the topographic connections by providing a lateral directed mapping f...

Face perception is modulated by sexual orientation

...the rewarding, evolutionarily adaptive value of an attractive face can be dissociated from its aesthetic value: for example, an attractive opposite-sex face may signal that a potential sexual partner has a healthy genotype, but an attracti...

Attractive birds more immune against bird flu

...es such as avian influenza. The white spot is also attractive to female birds searching for a mate. Evolutionary biologists have long attempted to explain why individuals of a species differ in appearance and why the choice of a mate is influenced by behaviour and appearance features that cannot reasonably be...

New nano-canary in the nanotoxicology coalmine: The body itself

...nsform infrared, FTIR, spectroscopy offers several attractive features for these investigations. These include the potential to detect biologically active nanoparticles without any prior knowledge of cell signaling pathways affected by them or need of a contrast agent to detect the biological response. Thus, ...

Male rivalry increases when females at most fertile, say researchers

...tion women tend to find masculine looking men more attractive and prefer their voices and odour. During this fertile phase women are more likely to have an affair with a masculine-looking man, as their features are linked to high testosterone levels, demonstrating good genetic qualities that can be passed on t...

Carbon nanotubes that detect disease-causing mutations developed by Pitt researcher

...NA molecules in this case-makes this approach very attractive for further development of label-free electronic methods," said Star, who is an assistant professor of chemistry at Pitt. Star and his colleagues at Nanomix also tested fluorescently labeled DNA molecules in order to confirm that DNA had attached to...

Ancient DNA helps UF researchers unearth potential hemophilia therapy

...ashington University in St. Louis. "They're a very attractive cell type to express it." It also was the first time researchers attempted such an approach on an animal so young. In adult mice, the immune system normally views clotting protein as an invader and rejects it after traditional gene therapy. But UF r...

Switching to new anti-bacterial targets: Riboswitches

...slightly, they suggest that a longer term and more attractive solution is to create entirely new drugs that target bacteria in completely new ways. This approach lengthens the useful clinical lifetime of a drug and makes it possible to tackle resistant 'superbugs' with combinations of drugs. The analog, pyrit...

Oysters: The natural way to protect our shores

...er reefs are self-sustaining, and are additionally attractive because they use native materials, have the potential for long-term growth, and contribute to overall ecosystem stability and quality. Oyster larvae move in groups and water-borne chemicals stimulate the oysters' settlement; reefs are therefore able...

Grasshopper love songs give insight into sensory tuning

...s howl or who have been riveted by the sight of an attractive person knows, nature has evolved sensory systems to be exquisitely tuned to relevant input. A major question in neurobiology is how neurons tune the strength of their interconnections to optimally respond to such inputs. Neuronal circuitry consists ...

Researcher at UGA College of Veterinary Medicine identifies new way of combating viral diseases

...and other components of this exit pathway might be attractive targets for antiviral therapies for a variety of viruses. Blocking Rab9 may have significant side effects, but there are people who live without Rab9, Hodge explained. Although they have metabolic problems, they are generally able to control their c...

New plant DNA libraries provides massive boost to world's plant researchers

... two key features that will make them particularly attractive to researchers. Firstly, there are genomic libraries from 20 different plant species, a far wider range than is available from other DNA library services. Secondly, the Warwick researchers have been able to create plant DNA libraries with large and "...

Researchers develop gene therapy to reverse pulmonary arterial hypertension

...normal human blood vessels, making survivin a very attractive target for selective intervention. "This makes the proliferation of lung blood vessels in this disease a 'form of cancer' or a form of neoplasia to be more precise, first proposed by Drs. Voelkel and Tuder from the University of Colorado. We've demo...

Unweaving amyloid fibers to solve prion puzzles

...s are also unusually robust, which also makes them attractive for nano devices. The advantage of the yeast protein is that it is not toxic, even for yeast. ...

Mayan stingless bee keeping: Going, going, gone?

...duce more honey, and therefore are an economically attractive option for bee keepers. In the Mayan tradition, a priest harvested stingless bee honey as part of a religious ceremony twice a year. Over harvesting kills the colony. Native bees may simply starve as deforestation, forest fragmentation and hurricanes...

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