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Tag: "attacks" at biology news

Silence the gene, save the cell: RNA interference as promising therapy for ALS

...y. ALS is a progressive neurological disease that attacks the motor neurons controlling muscles. Although its victims retain all their mental faculties, they experience gradual paralysis and eventually lose all motor function, becoming unable to speak, swallow or breathe. Known also as Lou Gehrig's disease,...

Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries

...ce for blood flow and can lead to angina and heart attacks in some people. Fatty buildups occur on the inner lining of an artery and gradually thicken into a plaque. As plaque grows, it narrows the artery more and more. When the plaque ruptures, blood clots form that can block the artery entirely. Low-densi...

Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients

...disease. It develops when the body's immune system attacks healthy nerve cells and disrupts normal nerve signaling. Patients experience a wide range of symptoms—including tingling, paralysis, pain, fatigue, and blurred vision—that can appear independently or in combination, sporadically or persistently. Alth...

Asthma gene clusters identified

Children who suffer from acute asthma attacks share a genetic profile that appears to be unique to these children, according to a new study by researchers at Cincinnati Children's Hospital Medical Center. The discovery opens the door to the possibility of designing treatments specifically tailor...

New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines

...stem destroys these types of antibodies to prevent attacks against self. The Duke study suggests HIV vaccines may have failed in part because certain proteins on HIV's protective outer coat trigger only short-lived, self-reactive antibodies instead of long-lasting, HIV-specific antibodies. The results also ...

Vascular structure and function improve with diet and exercise

...r the risk of high blood pressure, diabetes, heart attacks and stroke," said presenter and lead author Kunihiko Aizawa, M.Sc., a Ph.D. candidate at the University of Western Ontario in London, Ontario, Canada. "We found that there probably are some things that happen in even eight weeks." Researchers studie...

Implanted Devices Detect High-Risk Heart Failure Patients

...rtery disease, high blood pressure, previous heart attacks and valve problems. An estimated 4.7 million Americans suffer from the condition, with 400,000 new cases reported each year. Roughly one-half of patients die within five years of diagnosis. Although there is no cure, drugs can improve the strength o...

Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation

...rom donated stem cells will be available to launch attacks on the patient's cancer cells--the so-called "graf...r surface. The target that a T cell recognizes and attacks depends on the makeup of its receptor, which is constructed of protein building blocks. Each protein...

Vital step in cellular migration described by UCSD medical researchers

...sorders where the body's immune system incorrectly attacks the body's own tissue." From the genesis of human life to birth and beyond, cell migration is a complex, extremely important process that is not completely understood by researchers. In order to move, a cell must be polarized so that the molecular p...

In the sea slug's defense against lobsters, confusion is key

...edators, but the mechanisms by which such chemical attacks actually work against their intended targets are not well understood by researchers. New work has now shown that such chemical defenses can involve modes of trickery that had not previously been appreciated as components of chemical defense. When at...

Molecular machine may lead to new drugs to combat human diseases

...ed an intron from a bacteriophage, a molecule that attacks bacteria, to obtain an intron crystal structure trapped in the middle of the cutting and pasting cycle. As introns proceed through their work cycle, they change shape by folding and bending. By crystallizing the complex at various stages, the scienti...

Scientists seek answers on what activates deadly anthrax spores

...stop anthrax remains high, not only after the 2001 attacks through the mail that resulted in 18 cases and five deaths, but also after the recent scare at two military mailroom facilities when anthrax alarms went off. The group also would like to understand another closely related bacterium, Bacillus cereus,...

Computers to be used to find blueprint for new influenza drug

... the cells in our throats that the flu virus first attacks when a person becomes infected. The flu virus would be deceived into attacking the drug, called an inhibitor, instead of the cells. The three-year project will be largely carried out by examining the behaviour of atoms of the influenza virus which a...

Novel antiviral technology inhibits RSV infection in mice

...noparticle and gene silencing technologies thwarts attacks ofrespiratory syncytial virus (RSV) -- a virus associated with severebronchitis and asthma, an animal study by University of South Floridaresearchers found. The study was reported in the January 2005 issue ofthe journal Nature Medicine.RSV infects lu...

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