UCR researchers design chip that can improve citrus varieties
...what happens in cells when a citrus plant is under attack from a virus. And with this chip we can better understand what happens at the cellular level when oranges are put in cold storage after they are harvested, leading eventually to better methods of storage that improve fruit flavor." Manufactured by ...How nice, brown rice: Study shows rice bran lowers blood pressure in rats
...nts and thus decreases their risk of stroke, heart attack and kidney disease. But the drugs can also carry side effects: chronic cough, allergic reactions, dizziness, even kidney problems. What if some component of our diet could work in similar fashion, with few or no side effects? Researchers at Tohoku U...The critical importance of mangroves to ocean life
... half of the dissolved organic matter survives the attack from sunlight or bacteria. The authors measured the chemical signature in water samples from the massive mangrove forest in northern Brazil, using natural carbon isotopes and nuclear magnetic resonance spectroscopy--an established and common techni...USC researchers investigate protein that protects tumors
... tumor cells from any defenses the body deploys to attack them. "There are means in the body to kill tumor cells," Gill says. "[If] you block those then you give the cells the opportunity to survive and grow." Not only did EphB4 block those defenses, but it helped the cancer cells flourish by issuing a cal...Attacking cancer's sweet tooth is effective strategy against tumors
...er has been largely ignored. Few have attempted to attack specific points along the glycolytic pathway to ga...fect. "LDHA could be one weak point that we could attack but maybe, if we understand exactly all the steps involved, we could devise alternative strategies t...UC Davis study finds HIV hiding from drugs in gut, preventing immune recovery
...alled T-helper cells, organize the immune system's attack on disease-causing invaders. They are, however, the targets of the virus and their numbers decrease as the amount of HIV increases, leaving the body vulnerable to a variety of infections. Last year, Dandekar's team published a study of HIV-infected...New understanding of COX-1 and COX-2 enzymes could revise classification of pain meds
...ow associated with an increased incidence of heart attack and stroke. Researchers looked at mice that were genetically modified so that their COX-2 was inhibited ?to create a physiology in mice that roughly mimics that of users of COX-2 inhibitors. They found that the COX-1 enzymes in the mice "hooked up" i...One-third of adults with diabetes still don't know they have it
...-diabetes substantially raises the risk of a heart attack or stroke even if type 2 diabetes does not develop. People with pre-diabetes may have IFG or impaired glucose tolerance (IGT) or both. In IFG, blood glucose is high (100 to 125 milligrams per deciliter or mg/dL) after an overnight fast but not h...RNA interference stops colon cancer spread in mice
...ists have already developed chemical inhibitors to attack the pathway (some of which are now in clinical tri...as a way to sensitize tumors and launch a combined attack that will allow us to achieve much better results with reduced side effects." ...Adult stem cells are touchy-feely, need environmental clues
...c tissue may have been so damaged during the heart attack that the stem cells do not recognize the microenvironment as a guide for turning into heart muscle," Discher said; "however, our studies show that it might be possible to 'prime' stem cells for therapy in the lab, before implanting them in the heart,...Scientists stop autoimmune disease without shutting off immune system
...amage. Autoantibodies are immune-system cells that attack the body's own tissues. In a mouse model of pemphigus vulgaris, the researchers prevented blistering and other signs of the disease by injecting a drug that inhibits the p38 enzyme. Tests showed that the p38 inhibitor drug didn't prevent autoantibo...Scientists aim to thwart use of flu as bioweapon
...cells and begins churning out viral particles that attack the body. The immune system falls back on an array of cells, especially antibody-producing B-cells and flu-killing T cells, to fight back. Understanding just how that occurs, and simulating that with computers, is the goal of the center. Wu points t...Buckyballs boost antibody's chemotherapy payload
...roteins created by the immune system to target and attack diseased or invading cells. Previous work at M. D. Anderson has shown that ZME-018 can be used to deliver drugs directly into melanoma tumors, and work at Rice has shown that Taxol can be chemically attached to a buckyball. "The idea that we can po...The molecular mechanism of a diabetes vaccine revealed
...es occur when certain T cells in the immune system attack the body's own cells and tissues. The scientists discovered that p277 directs the activity of the immune system in two ways. First, the p277 peptide steps up the activities of a different type of T cell that regulates the amount of potentially harmfu...How HIV 'exhausts' killer T cells
...IV) "exhausts" killer T cells that would otherwise attack the virus. The researchers found that HIV can simp...immune reactions that trigger the immune system to attack the body. Walker added that the researchers' findings will also likely have application in understan...A new tool against brain disease
...IV) "exhausts" killer T cells that would otherwise attack the virus. The researchers found that HIV can simp...immune reactions that trigger the immune system to attack the body. Walker added that the researchers' findings will also likely have application in understan...Global study shows all tobacco bad for the heart
...om 52 countries, they calculated the risk of heart attack for various forms of active tobacco use (both smok...ther lifestyle factors that could affect the heart attack risk, such as diet and age. They found that tobacco use in any form, including sheesha smoking po...New GI technologies improve internal organ visualization
...tients who have damaged heart muscle after a heart attack and may benefit from the injection of therapies directly into the muscle without another operation." Endoscopic Ultrasound (EUS)-Guided Angiography: A Novel Approach to Diagnostic and Therapeutic Intervention in the Vascular System [Abstract W1321...Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial
...livery system for short interfering RNA (siRNA) to attack cancer, says senior author Anil Sood, M.D., associate professor in the Departments of Gynecologic Oncology and Cancer Biology at M. D. Anderson. "Short interfering RNA is a great technology we can use to silence genes, shutting down production of ...HIV infection requires an accomplice: B cells with special protein direct HIV to T cells
...et another pathway the virus uses in its insidious attack on the immune system, University of Pittsburgh researchers will report at the XVI International AIDS Conference (AIDS 2006). "The research supports a new role for B cells in the development and spread of HIV between cells, with important implicatio...