Study shows combination of immune substances to be safe
...on is used alone to stimulate the immune system to attack certain cancers. This strategy, a form of immunotherapy, is sometimes used to treat melanoma, advanced kidney cancer and other tumors that respond poorly to chemotherapy or radiation therapy. But interferon can have serious side effects that limit it...Biologists discover new pathway into plant cells
... percent. These fungi produce multiple toxins that attack wheat plants, reducing yields and ruining wheat used as seed. In the United States, it's a particular problem in the Great Plains and Midwest. Ciuffetti has spent much of her career studying these "host-selective" toxins. "Until now, we didn't reall...'Good' bacteria could save patients from infection infection by deadlier ones
... avenue for the more virulent forms of bacteria to attack patients. This is so because these "preventive" measures destroy beneficial bacteria, while at the same time the more "nasty" bacteria are often able to survive by adapting themselves to the pharmacological means used against them. Since different ...Access to existing medical treatments could save more lives than spending to improve the treatments
...e, Woolf and Johnson estimate that for every heart attack death prevented by the development of the new statin, Crestor, seven deaths would have been prevented by sticking with older, less potent statins but adopting simple reminder systems such as post-it notes on the front of charts that would alert clini...Scientists directly view immune cells interacting to avert autoimmunity
...round the dendritic cells where they are primed to attack the body's own tissue -- the cause of type 1 diabetes, arthritis and other autoimmune diseases. The scientists showed that Treg cells prevent this destructive response after they and the T helper cells independently interact with dendritic cells. Th...UCSD study finds anthrax toxins also harmful to fruit flies
...ects of anthrax toxins. Learning how these toxins attack developing and adult tissues is important because it can help scientists understand how they function at the molecular level and may lead to new therapeutic strategies for neutralizing their effects in humans. Annabel Guichard, a biologist at UCSD a...MRSA use amoeba to spread, new research shows
...celled organisms, they have acquired the skills to attack us". For these reasons, such primitive cells are being used to replace animals for many kinds of biological tests. "Effective control of MRSA within healthcare environments requires better understanding of their ecology," said Professor Brown. "...Ancient DNA helps UF researchers unearth potential hemophilia therapy
...on and trying to find a way to overcome the immune attack when performing gene therapy on adult animals. "I don't think the research is done," Mah said. "But this is definitely a step forward for hemophilia gene therapy." ...Simple idea to dramatically improve dengue vaccinations
...fies three to five T-cells that best recognize and attack the components of the sickened cells. Once the cells are selected, they are produced by the millions and sent out to clear the infection. After the infection is gone, thousands of these pre-programmed T-cells remain in the body, lying in wait should ...New drug could reduce tissue damage after heart attack
...n contributes significantly to the extent of heart attack damage and this can be exacerbated by CRP. The UC...severity of damage in experimental models of heart attack and stroke. This first identified CRP as a valid therapeutic target. The present collaborative stud...Melanoma vaccine strategy shows promise in laboratory experiments
...to stimulate immune cells called killer T cells to attack the melanoma cells. Another type of immune cell ca... BRAFV600E, to the killer T cells to trigger their attack on the melanoma cells. "In our experiments, we saw a strong cancer-killing immune response when kil...Mice studies illustrate potential of chimp/human antibodies to protect against smallpox
... disease in 1980. However, concerns of a bioterror attack involving the highly contagious and fatal virus ha...p effective measures against a potential bioterror attack involving the deadly smallpox virus," says NIH Director Elias A. Zerhouni, M.D. "It is imperative t...Defective immune system response to smallpox vaccine detailed in new study
...t concerns about the possibility of a bioterrorist attack using smallpox virus prompted authorities to reinstate voluntary smallpox vaccination for specific groups, such as military personnel. In the first five months of 2003, the U.S. Department of Defense vaccinated more than 450,000 personnel against sma...Gene patterns in white blood cells quickly diagnose disease
...ld be used at the site of a suspected bioterrorism attack to determine who has been exposed within hours instead of days that would be required using traditional culture methods. "The technology is not there yet, but within 10 years this test could also be done in doctors' offices for a variety of commo...Stem cell study for patients with heart attack damage seeks to regenerate heart muscle
...ent. "A person who has had a single, severe heart attack may survive but can be left with substantial damag...e originally located. In animals that had a heart attack induced, the MSCs given intravenously followed the signals to the injured section of the heart and a...Aspirin reduces cardiovascular risks in men and women -- but differently
...nts -- a combined endpoint including stroke, heart attack and death due to cardiovascular disease -- in both men and women, according to a new meta-analysis of more than 95,000 patients by a Duke University Medical Center cardiologist. However, the researchers found, the major reasons for the risk reductio...Study in Science holds promise for a new approach to drug therapy
... carry nerve messages, enable white blood cells to attack infection and set the timing of the heartbeat. Fau...ing a signal that the cell needs to move in on and attack invading viruses. In heart muscle cells, a similar mechanism controls heart beat rate. Many curren...Weizmann Institute suggests that immune cells help to maintain cognition and brain cell renewal
...hat T cells directed against CNS components do not attack the brain but instead, recruit the help of the brain's own resident immune cells to safely fight off any outflow of toxic substances from damaged nerve tissues. In the present study, the scientists showed that the same immune cells may also be key ......ers of antibiotics is choosing the proper point of attack against bacteria. There are hundreds of possible p...rotein databanks and identified possible points of attack for antibiotics. Bumann and his team then examined what role these proteins play in a Salmonella in...... the throat and ears, or Norwalk viral agents that attack the GI system, and so on. While the world's attention has migrated to bird flu, not a single person in the western hemisphere has contracted the deadly form of the disease. And though "regular" flu is still a potent threat, expected to kill more tha...