Mass production of human papillomavirus could lead to gains against cervical cancer
...o vaccines that would trigger the immune system to attack at an earlier stage in the virus's life cycle to stop HPV before it can replicate. The researchers, led by Paul Ahlquist, a Howard Hughes Medical Institute investigator, published an article describing their new technique on June 13, 2005, in the ea...Survival of heart patients on beta-blockers varies greatly with genetic variation
Survival of heart attack and unstable angina patients placed on beta-blocker therapy corresponds to specific variations in their genes, according to a study by researchers at Washington University School of Medicine in St. Louis and the Mid America Heart Institute in Kansas ...New Lab Research May Help Those Deafened By Immune System Attack
... be a main target of the immune system's deafening attack on the inner ear. IESCA is found in the supporting cells that help make up the organ of Corti, a tiny but crucial structure inside the cochlea, or inner ear. Inside the organ of Corti are the ultra-sensitive hair cells, whose movement in response to...Discovery of T-cell 'traffic control' boosts new drug promise
...a debilitating disease in which the body's T cells attack the myelin coating of nerve cells and disrupt their function. Neither Goetzl nor Rosen is involved in the on-going clinical trials of the new drugs and neither has financial ties to the companies that manufacture them. Controlling this process with ...Monkeying around to improve organ transplantation
...herefore, specific suppression of the T cells that attack the transplanted organ is needed. It was known that anergic T cells (immune T cells that do not respond to antigen stimulation) generated in an artificial environment outside the living organism have immunosuppressive activity in vitro. Now in a stu...Sleeping beauty plays a significant role in identifying cancer genes
...rug; it is going to take a combination of drugs to attack the pathways that are required for cancer to start and continue growing." The next step for Largaespada, Jenkins, Copeland and their colleagues will be to generate and analyze a large number of other tumors induced in mice using the Sleeping Beauty ...Why do aneurysms form? New studies suggest leading role for white blood cells
...metalloproteinases and chemokines, which help them attack invaders," says Upchurch. "We wanted to see what the role of neutrophils was in the early stages of aneurysm formation and the progression of the aneurysm." Upchurch and his colleagues performed one of the studies using mice that had been treated wi...Ants, not evil spirits, create devil's gardens in the Amazon rainforest, study finds
...clude. Domatia To find out if worker ants only attack non-host plants, the scientists decided to mimic D. hirsuta's hollow stems, called domatia, which are the ants' primary nesting sites. Artificial domatia were constructed out of foil-wrapped test tubes partially filled with cotton. Two cedar sapling...Colorful bacteria more dangerous
...ive certain bugs their color also help them resist attack by immune cells called neutrophils. Scientists and clinicians have known for many years that gold-colored strains of a bacterium called Staphylococcus aureus tend to be cause more disease than colorless strains. The color of these bugs comes from an...Progress on HIV/AIDS significant but insufficient
... it ever more necessary to establish programmes to attack the vulnerability of women and girls. Among the recommendations was the need to strengthen measures to combat discrimination against people with AIDS, to draw up special programmes for women and girls, and to enhance efforts to eliminate violence aga...Scientists create digital bacteria to forge advances in biomedical research
...would be undesirable. Preparing for a bioterrorism attack is one example. "You can actually try to simulate dangerous experiments," said Cluzel, an Assistant Professor in Physics. "For instance, if you mix a pathogenic strain with a friendly strain, which one is going to win, and with what kind of speed?" ...How HIV disables the cells' call for help
... it prevent these cells from mounting a full-scale attack against the invader? In research published today in the Journal of Clinical Investigation, a team at the Weizmann Institute of Science has shown how a part of a protein on the virus' outer surface interferes with the cells' normal immune response. Bu...Researchers discover new tumor defense system
... cancer may have a way of defending itself against attack by the immune system, thereby reducing the potential efficacy of novel anti cancer therapies that rely on a functioning immune system." The free fatty acids act against cytotoxic T lymphocytes by blocking a number of the lymphocytes' signaling event...Promising therapies for haemophilia & heart disease
... clots in the heart or brain can result in a heart attack or stroke. Our studies in mouse models have shown that inhibition of P-selectin reduces atherosclerosis (hardening of the arteries) and the work of our collaborators shows that the events leading to deep vein thrombosis are reduced. P-selectin inhibi...Scavenger cells could be key to treating HIV-related dementia
...where many memories are stored in their attempt to attack the virus there, according to findings reported in the Journal of Virology this month. Researchers found that HIV-infected macrophages in the brain continuously travel to the temporal lobe, a part of the brain Alzheimer's disease often damages. Beca...Optimizing cell therapy against tumors is a balancing ACT
...ells that stimulate the T cells to cause an immune attack can be identified. The T cells get expanded and re-infused into the patient to mount an immunological, anti-cancer response against the tumors. One of the challenges faced is selecting the appropriate T cells with proper antigen specificity. In a ne...Tiny avalanche photodiodes target bioterrorism agents
...he threat of a larger and more deadly bioterrorism attack -- perhaps from smallpox, plague or tularemia -- b...tect such biological agents and rapidly contain an attack is still being developed. In a significant finding, researchers at Northwestern University's Center...Immune system has evolved to prevent autoimmune disease
...he improved antibodies would be far more likely to attack the body's own tissues. The Rice University study ...1,000 times more likely to produce antibodies that attack healthy tissues." Antibodies that bind with something other than the antigen they evolved to attack...New study finds how cells with damaged DNA alert the immune system
... the natural killer (NK) cells - which are able to attack tumors - can differentiate cells that are cancerou...n that the immune system is designed to detect and attack foreign invaders, but cancer cells present a special challenge because they are still the bodies own...... the natural killer (NK) cells - which are able to attack tumors - can differentiate cells that are cancerou...n that the immune system is designed to detect and attack foreign invaders, but cancer cells present a special challenge because they are still the bodies own...