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Tag: "attack" at biology news

Jump-starting T Cells In Skin Cancer

...ber of immune cells called killer T cells that can attack the tumor. In an unexpected finding, however, they...hat other T cells can snap out of their stupor and attack the tumor. ...

Fox Chase Cancer Center scientists identify immune-system mutation

...her T cells are known as killer cells because they attack foreign invaders more directly. "The maturation of T cells involves key branch points at which cells choose one of two different pathways, going on to become helper cells or killer cells," Kappes said. His goal is to understand how T cells specializ...

Computers to be used to find blueprint for new influenza drug

...he behaviour of atoms of the influenza virus which attack cells, and atoms of the throat cells that are attacked. By using advanced software to model the way these atoms behave in highly complex interactions, the atomic structure of a suitable drug can be worked out. Using computer modelling in this way ca...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

...as searching for new targets, finding chemicals to attack knowntargets, and posting data from related chemistry and biologyexperiments. Volunteers could use chat rooms and bulletin boards toannounce discoveries and debate future research directions. Over time,the most dedicated and proficient volunteers wou...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...nd enter a dormant state ?these are the hardest to attack with drugs." ...

Researchers reveal the infectious impact of salmon farms on wild salmon

...ice increases, we are now realizing that lice will attack other species, not only salmon, but other fish such as herring which are the spark plugs of the entire ecosystems ?everything depends on them ?from salmon to whales to seabirds. Every commercially important fish is either directly or indirectly depen...

Poplar trees redirect resources in response to simulated attack

...ble to help the plant spring back to life once the attack has passed. Using the techniques developed at Broo... redirecting their nutrients away from the site of attack and placing them into storage for later regrowth," Ferrieri said. Supporting evidence comes from th...

In the sea slug's defense against lobsters, confusion is key

...f chemicals that together comprise a multi-pronged attack on the predator's nervous system, resulting in the usurpation of its normal behavioral control system and a confused response that facilitates the slug's ultimate escape. The team of researchers conducting the study, Cynthia Kicklighter, Zeni Shaban...

Taking Aim With Nanoparticle PEBBLEs

...exposure to light. Unlike chemotherapy drugs that attack tumors by invading cancer cells and disrupting their DNA, PEBBLEs never enter the cells they target. Instead, they attach to the outside of the targeted cell and shoot reactive oxygen species into it, setting off "an avalanche of damage," said Kopelm...

Genetically modified natural killer immune cells attack, kill leukemia cells

...rful "on-switch" that prompts them to aggressively attack and kill leukemic cells. This finding, from researchers at St. Jude Children's Research Hospital, suggests a way to improve the outcome of children who receive treatment for acute lymphoblastic leukemia (ALL) or other blood cancers. Results of the S...

UCSD researchers maintain stem cells without contaminated animal feeder layers

...d into people, they would provoke an immune system attack eliminating their therapeutic value. While several laboratories have attempted to grow stem cells in alternative cultures, problems have remained. In some cases, human feeder layers were developed but this added another measure of complexity to the ...

Scientists reveal molecular secrets of the malaria parasite

...resent a mechanism by the parasites to repulse the attack of thehost's immune system. * For the first time, ...nes" —that is, vaccines which raiseantibodies that attack the parasite in the vector. (Such antibodies arein the "blood meal" and still work for an hour or so...

Study Models Impact Of Anthrax Vaccine

... found that anthrax vaccination given evenafter an attack could be beneficial in reducing the length of timeantibiotic treatment would be needed. These findings could be animportant tool for policymakers who must develop effective strategiesfor containing an anthrax outbreak. The study is published in theDe...

Unexpressed But Indispensable -- The DNA Sequences That Control Development

...ifficult. In this issue, Greg Elgar and colleagues attack this problem by comparing the non-coding sequences of the human and the pufferfish. Since the last common ancestor of these two species existed 450 million years ago, the authors reasoned that non-coding sequences conserved between them are likely t...

New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines

...road range of pathogens. These antibodies can also attack the body itself, as in autoimmune disorders such as systemic lupus erythematosus. When viruses activate innate B cells, the body destroys the B cells to protect against autoantibodies that could cause autoimmune disease or other harm. The second imm...

Antibiotic might fight HIV-induced neurological problems

...CP-1 protein, when secreted from brain cells under attack from HIV or SIV, attracts infection-fighting cells known as macrophages, which then enter the brain. The influx of these cells contributes to swelling and inflammation known as encephalitis. The other protein, p38, helps trigger a series of events th...

Asthma gene clusters identified

...ound that children who were having an acute asthma attack had a gene expression profile that was clearly different from those seen in someone with stable (controlled) asthma. The amazing thing was that the gene expression profiles were consistent across patients, despite the likely differences with respect ...

Mayo Clinic Researchers Create 'Obedient Virus'; First Step To Use Measles Virus Against Cancer

...mandeering cells, and then redirected the virus to attack diseased, rather than healthy cells. The work was done on laboratory animals implanted with two kinds of human cancer cells -- ovarian cancer and lymphoma -- and is probably still years away from use as a human therapy. But the concept has at last be...

US life expectancy about to decline, researchers say

...ion, Type 2 diabetes, raises the prospect of heart attack becoming a common condition of young adulthood." The authors expect that this study will raise awareness of the importance of increased funding for obesity research and treatment, especially in children. They also point out that new investment into ...

Chemists identify immune system mechanism for methamphetamine binges

...t the drug can engage the body's defense system to attack methamphetamine in such a way that makes users inc...ies to the pathogen, antibodies to methamphetamine attack and begin to clear the drug, Janda says. If the antibodies prevent some of the drug from reaching it...

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