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Tag: "attach" at biology news

Scientists develop nanotech-laser treatment that kills cancer cells without harming healthy tissue

...teresting ways we can do this. For example, we can attach an antibody to a carbon nanotube to target a particular kind of cancer cell." One example is lymphoma, or cancer of the lymphatic system. Like many cancers, lymphoma cells have well-defined surface receptors that recognize unique antibodies. When at...

Biotechnology's newest chemical tool

...s require a source for the methyl groups that they attach to DNA, and most often that source is a molecule c...masauskas and colleagues wanted the flexibility to attach more than just a simple methyl group. In this study, the scientists demonstrated that methyltransfe...

Researchers learn how blood vessel cells cope with their pressure-packed job

...e to the membranes in a manner similar to how they attach to underlying blood vessel tissue in the body. The... of adhesion sites where those stress fibers would attach to the cell membrane."These new results clearly show that Rho and physical stresses cooperate to pro...

New possibilities for flu antiviral and vaccine research emerge from 'Spanish flu' virus

...hemagglutinin surface protein that helps the virus attach to cells and replicate properly. This gene seemed to be responsible for much of the severe lung damage reported in people infected with the Spanish flu. The three genes encoding the viral "polymerase" enzymes, which form the virus' basic replication ...

Bacterial protein mimics host to cripple defenses

...in ligase, an enzyme plant and animal cells use to attach the small protein ubiquitin to unneeded or defective proteins. Other enzymes then chew up and "recycle" the ubiquitin-tagged proteins. To confirm that AvrPtoB was a molecular mimic, Martin and Abramovitch altered parts of the protein that correspond...

Bare metal stents deliver gene therapy to heart vessels with less inflammation in animal studies

...f Philadelphia have developed a novel technique to attach therapeutic genes to a stent's bare metal surface. This technique allows the genes to help heal the surrounding blood vessels, while avoiding the inflammation caused by polymer coatings. The research team reported their proof-of-principle study, us...

Antibacterial coatings cut infection rates

...he biofilm and eventually die on the surface. "We attach the furanones by covalent bonding to our biomedical devices. We stress covalent bonding because it is important that we anchor them very firmly to the surface, making it impossible for them to break away and travel into remote organs such as the brai...

Depression model leaves mice with molecular scar

...ethylation. Methyl groups, the silencer molecules, attach themselves to the histones, turning off the gene. ...hanism, acetylation, in which molecular activators attach themselves to the gene and overcome the silencer molecules. Imipramine turned off an enzyme (Hdac5) ...

Patterns in genome organization may partially explain how microbial cells work

...articular way inside the cell. New techniques that attach fluorescent "reporter" markers to predetermined spots on chromosomes have indicated that many bacterial genes tend to be found at specific cellular locations. Patterns are not obvious in the sequences of prokaryotic genomes, which led the team led by...

Neurons find their place in the developing nervous system with the help of a sticky molecule

...ell adhesion molecule ?a protein enabling cells to attach to other surfaces, something that they must do either to move or sit still and elaborate connections. They also showed that MDGA1 is expressed on subpopulations of migrating neurons throughout the developing nervous system, including layer 2/3 neuron...

For one Stanford doctor, the beat goes on during open-heart surgery

...ing for the right spot on the back of the heart to attach the next vessel. Ihnken, MD, clinical assistant professor of cardiothoracic surgery at the Stanford University School of Medicine, was using an innovative technique called "beating-heart" surgery for coronary bypass. It replaces the more conventiona...

Anthrax spores may survive water treatment

...tional drinking water disinfection methods and can attach themselves to the inside surface of water pipes, s.... Calomiris also tested the ability of spores to attach to the inside of pipes, by running contaminated water in a continuous loop through sections of pipe ...

Cholesterol gets 'thumbs up' for role in digit development

...h only half of their Sonic hedgehog proteins could attach to cholesterol. Those mice developed normal digits 2 through 5 (index through pinkie), but had duplication of these digits anteriorly. The findings suggested that Sonic hedgehog without cholesterol traveled further than normal, triggering the anoma...

'Nano-keys' bind cell receptors and trigger allergic reactions

... and cause IgE-receptors to cluster when the cells attach to the surface. This activates the cell's inner machinery. Said Baird: "In this way, we can control what the cell sees. The cells are binding to the engineered surfaces and getting turned on. We can then see how the cell is organizing itself due to...

NJIT engineer poised to take stem cell research a step forward

...ffolds. Scaffolds are biomaterials that stem cells attach to and, with a bit of luck, grow into the cellular building material of tissue. Under a microscope, the nano-scaffolds look like infinitesimally small (400-500 nanometers in diameter) fiber meshes, said Arinzeh. "We are eager to see," said Arinzeh, ...

Absence of critical protein linked to infertility

...say, an embryo cannot survive in uterine tissue or attach to a mother's blood supply. Other genes also play roles, but C/EBPb is critical for implantation of an embryo, said Milan K. Bagchi, a professor of molecular and integrative physiology. C/EBPb is scientifically known as CCAAT/Enhancer Binding Protei...

USC, Rice to develop bacteria-powered fuel cells

... understand how the bacteria Shewanella oneidensis attach to and interact with anode surfaces inside the fue...chnique to examine how the cigar-shaped Shewanella attach themselves to crystalline surfaces. The researchers found that Shewanella would lay flat and orient ...

Bioactive cement scaffold may improve bone grafts

...e similar to mineral in bone so that cells readily attach to the scaffold." The researchers used mouse bone cells in their experiments, but in practice surgeons would use cells cultured from patient samples. In addition to creating pores in the hardened cement, the natural polymer beads protect the cells d...

New insight into machinery of immune cells' 'tentacles'

...in filament formation is crucial for the T cell to attach to APCs, called B cells, which collect and display foreign proteins from invading microbes. The ensuing "conversation" between T and B cells enables the T cell to effectively identify and target such invaders for destruction. The site of contact bet...

Tumor cells that border normal tissue are told to leave

...mor cells were shown to lose surface proteins that attach them to other cells and stabilize their position within tissues. The study demonstrated that it was the difference in Src activity that led to the change in the attachment proteins. When a high Src cell (tumor cell) was next to a low Src cell (normal...

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