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Tag: "attach" at biology news

Health costs soar as 60 million Americans classed as obese

...ded RNA. Through specific chemical reactions, they attach two strands of DNA, each resembling one side of a ladder. The two DNA strands spontaneously bind together, then the researchers add magnesium ions to initiate folding of the RNA. "Folding of the RNA structure competes with formation of the DNA const...

Modified collagen could yield important medical applications

...Materials Science and Engineering. "If you want to attach these molecules to collagen, you don't have to coo...medical treatments, Yu says, because it is easy to attach bioactive agents to the peptides. When the peptides bind with collagen, these attached agents can dr...

Unusual antibiotics show promise against deadly 'superbugs'

...Materials Science and Engineering. "If you want to attach these molecules to collagen, you don't have to coo...medical treatments, Yu says, because it is easy to attach bioactive agents to the peptides. When the peptides bind with collagen, these attached agents can dr...

Purdue scientists may have found key to halting spinal cord damage

...nts - such as vitamins C and E - which are able to attach themselves to free radicals, detoxifying them. While there is nothing inherently wrong with this approach, Shi said, it might not be getting at the root of some health problems. "Antioxidants are good scavengers of free radicals, and it's certainly ...

Scientists discover that three molecules may be developed into new Alzheimer's drugs

...said Kosik. "This means that many phosphate groups attach to tau--modify it--and cause it to become dysfunctional." The culprit is an enzyme, called CDK5, that attaches the phosphate to the tau protein, facilitating the disease process. The researchers set out to find a way to inhibit this enzyme, to keep ...

Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels

...said Kosik. "This means that many phosphate groups attach to tau--modify it--and cause it to become dysfunctional." The culprit is an enzyme, called CDK5, that attaches the phosphate to the tau protein, facilitating the disease process. The researchers set out to find a way to inhibit this enzyme, to keep ...

Promiscuous Catalytic Activity Possessed by Novel Enzyme Structure

...l number of molecules, this new enzyme was able to attach prenyl groups to most of the different aromatic compounds tested. Some of the newly-formed hybrid molecules had previously been found in natural sources, but the enzyme also built some new compounds that had never been seen before. The key to Orf2’s...

Stem cell training program to make its Stanford debut

...l number of molecules, this new enzyme was able to attach prenyl groups to most of the different aromatic compounds tested. Some of the newly-formed hybrid molecules had previously been found in natural sources, but the enzyme also built some new compounds that had never been seen before. The key to Orf2’s...

Gene therapy advance treats hemophilia in mouse models

...ified virus. This hybrid vehicle could more easily attach to certain liver cells and allow the genes within the vehicle to enter the cells. The genes then caused the liver cells to make the protein that prevents bleeding. The researchers also modified the vehicle so that it would express these therapeutic...

New lead reported in tumor angiogenesis

... trigger angiogenesis, tumor cells also physically attach to a protein displayed on the surfaces of cells that line the walls of our blood vessels. This physical interaction, like a finger pushing a button, sends a signal within these cells to grow and sprout new capillaries. The finding, while technical i...

Secrets to antibody's success against West Nile Virus surprise scientists

...ctations, it does not block the virus's ability to attach to host cells. Instead, the antibody somehow stops...o find that the antibody only seemed to be able to attach to 120 of the 180 copies of the target region in the complete viral envelope," says Grant Nybakken, ...

New technique rapidly detects illness-causing bacteria

...ther sequence of the S. pyogenes rRNA. The probes attach to the target rRNA sequence when the test tube is placed in a water bath for about 25 minutes at exactly 41 degrees Celsius (106 Fahrenheit). At that temperature, the complementary probe DNA sequence binds to the target RNA sequences. In a positive ...

Tagging pathogens with synthetic DNA 'barcodes'

...g cells consists of two complementary strands that attach to one another along their length. But Luo's research purposely and completely ignores the DNA's genetic coding properties. He uses DNA, he said, as a "generic instead of a genetic material." By synthesizing three short strands of DNA, each of which...

Why do aneurysms form? New studies suggest leading role for white blood cells

...rats that lacked the protein that lets neutrophils attach to tissue and start the "first aid" process. The r...n on the surface of neutrophils that allow them to attach to tissue. They studied L-selectin production in the aortas of rats that had been injured with elast...

Unweaving amyloid fibers to solve prion puzzles

...sary to understand how the prions that comprise it attach to each other. Krishnan was able to identify the precise segment at which the prions interact--something that no one had done before him with a real prion. To do this, Krishnan took a variety of yeast prion strains and modified them in such a way th...

Clearing jams in copy machinery

...acles encountered in the replication process. They attach themselves at the same time to one beta sliding clamp. Pol III copies the original DNA, and acts as a proofreader to catch any misspellings and cuts any base that is wrong. But Pol III is a perfectionist, and can stall if it encounters a problem. Pol...

Scientists find a maturity gene in fly

...receptor." Hormones like estrogen and testosterone attach to these receptors, which in turn attach to genes in cell nuclei to switch the genes on or off. Nuclear hormone receptors are found in all an...

MWG Biotech expands siMAX?siRNA portfolio with new scales, lengths and design tools

...receptor." Hormones like estrogen and testosterone attach to these receptors, which in turn attach to genes in cell nuclei to switch the genes on or off. Nuclear hormone receptors are found in all an...

North & South American researchers find architectural abnormalities in T. cruzi ribosome

..."For instance, the splice leader of the mRNA might attach at the turret, which may swivel out and drag the mRNA across the binding site on the ribosome to initiate protein translation." The findings may also advance studies of parasitic relatives Trypanosoma brucei, which causes sleeping sickness in Africa...

Immune system has evolved to prevent autoimmune disease

...es, or epitopes, where antibodies could mistakenly attach themselves to proteins in a healthy cell. The mutation response method employed by our adaptive immune system seems keyed to this number, producing antibodies that are statistically likely to mistakenly bond with healthy proteins slightly less than o...

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(Date:11/24/2009)...tute (LRI) today named 12 new grant recipients for...e innovative work across a broad spectrum of lupus... novelty, and potential to drive scientific discov...plex disease of systemic lupus. , The 2009 grant... across the nation and include interdisciplinary a...
(Date:11/24/2009)...of a remarkable class of ring-shaped protein motor...nce Berkeley National Laboratory (Berkeley Lab) us...mline at the Advanced Light Source (ALS). These pr... and replication, and are vital to the survival of...s, such as the human papillomavirus, which has bee...
(Date:11/24/2009)...ood is a matter of debate. A high-profile study a ...rcent of their carbon from trees and leaves, evide...and aquatic ecosystems. , But new research from ...ely to be true. Algae provide a much richer diet f...rch published this week in the Proceedings of the...
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(Date:11/27/2009)...nted medical, economic burdens, study predicts , ... number of people with diabetes in the United Stat... new study predicts. , That would bring the tot...isease, up from 23.7 million today. , , At the s...s will triple, the study also warns, rising from a...
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