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Tag: "attach" at biology news

New binding target for oncogenic viral protein

...brings them in close proximity to the enzymes that attach ubiquitin. The proteins recognized by Fbw7 play key roles in cell division, cell growth, differentiation, and cell death. "These proteins are also some of the most broadly acting cellular oncogenes, and include cyclin E, c-Myc, Notch, and c-Jun," no...

Plants respond similarly to signals from friends, enemies

...nts from a distance and therefore does not need to attach itself to the plant to elicit a response. When the researchers studied L. japonicus plants missing the receptors that receive signals from other organisms ?certain genes in the plant were modified to accomplish this ?they discovered that the plants ...

Needling Chromosomes Reveals Cell Division Secret

...e to be held together, becauseotherwise they don’t attach to the apparatus called the spindle thatdistribute...re held together, then onereplicated chromatid can attach to one pole and the other to theopposite pole. But if they are not held together, they attachindepen...

Taking Aim With Nanoparticle PEBBLEs

...s never enter the cells they target. Instead, they attach to the outside of the targeted cell and shoot reactive oxygen species into it, setting off "an avalanche of damage," said Kopelman. By staying outside the cell, PEBBLEs avoid a problem that thwarts many chemotherapy drugs. "The really bad cancer cel...

UCLA scientists transform HIV into cancer-seeking missile

...which ordinarily infects T-cells, to hunt down and attach to P-glycoproteins -- molecules located on the surface of many cancer cells. The UCLA team is the first to prove that modified HIV will target and bind with P-glycoproteins. "P-glycoproteins cause big problems by making the cell resistant to chemoth...

Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease

...g chained polyethylene glycol molecules. They then attach one such tethered monomer to a microscope slide and the other to the AFM microscope tip. They can then bring the isolated and suspended molecules together to study how and whether they interact. The Duke researchers study these interactions by retra...

Protein offers way to stop microscopic parasites in their tracks

...ein on it. The adhesive protein allows the host to attach to the exterior of the host cell. The resulting contact points give the belt something to push against as it moves backward, in turn pushing the parasite forward. But these adhesive spots have a significant disadvantage in comparison to a chain: if ...

Nano-bumps could help repair clogged blood vessels

...ents that bone and cartilage cells in petri dishes attach better to materials that possess smaller surface b...nd interfere with blood flow. "If a stent doesn't attach firmly it can become loose, and parts of it will actually break off and go down the bloodstream," We...

New polysaccharide may help combat multidrug resistance in cancer

...cond, it forms a template to which matrix proteins attach and form important extracellular structural complexes." Hyaluronan also accumulates around the outside of cells during disease processes such as early atherogenesis, persistent inflammation, and cancer. In recent years, however, hyaluronan has also ...

New strategies to reduce hospital-aquired infections

... is a community of numerous types of microbes that attach to internal pipe surfaces, faucets and showerheads where they thrive and multiply. The force of water passing through the pipes or tap can break off fragments of the biofilm transferring it to different parts of the water distribution system and seed...

Distributed Basic Local Alignment Search Toolkit (W.ND-BLAST)

... is a community of numerous types of microbes that attach to internal pipe surfaces, faucets and showerheads where they thrive and multiply. The force of water passing through the pipes or tap can break off fragments of the biofilm transferring it to different parts of the water distribution system and seed...

Nature provides inspiration for important new adhesive

...s amazed at the ability of these small mollusks to attach themselves so strongly to rocks," said Li, who is ... the mussels' byssus, which are small threads that attach them to rocks and other surfaces. The byssus thread is a protein with a very unusual composition - a...

Newly Discovered 'Branding' Process Helps Immune System Cells Pick Their Fights

... cells in several distinct ways. For example, they attach a nitrate group to the amino acid tyrosine in the peptides, changing it to nitrotyrosine. Unanue's lab then showed that these changes increased the chances that various types of T cells would react to the modified peptides shown to them by antigen-p...

15-year hunt finds cause of pseudothalidomide syndrome

...iding cell. Once lined up, tiny molecular "motors" attach to the centromere of each copy and pull the original and the new copy away from each another as division proceeds. However, in cells from people with Roberts syndrome, the chromosome copies are frequently not attached to each other at their centrome...

Microarrays as phenotype

...f functional DNA on glass slides. Then researchers attach fluorescent labels to nucleic acids (DNA or RNA) from the cells under study. These labeled nucleic acids are allowed to bind to the DNA on the slides. Researchers then use a microscope to measure how much of a specific nucleic acid is present. Genot...

Purdue researchers use enzyme to clip 'DNA wires'

...umerous sequences, and various restriction enzymes attach to and cut specific sequences, enabling scientists to isolate and snip DNA segments of differing lengths. The enzyme used in the Purdue research cuts segments of DNA containing a sequence of GGATCC. "We incubate the particles and DNA in a solution, ...

Engineers improve plastic's potential for use in implants by linking it to biological material

...o a smaller protein piece that human cells like to attach to, polypyrrole gained the ability to attach to cells grown in flasks in the laboratory. "It will be very useful from a biomedical standpoint to...

Atmosphere may cleanse itself better than previously thought

...eactive group of chemicals called OH radicals that attach themselves to hydrocarbons and rip them into inert pieces." OH radicals arise naturally from many atmospheric constituents, and the effect they have on pollution has long been factored into models that describe the atmosphere and attempt to predict ...

DNA constraints control structure of attached macromolecules

...ded RNA. Through specific chemical reactions, they attach two strands of DNA, each resembling one side of a ladder. The two DNA strands spontaneously bind together, then the researchers add magnesium ions to initiate folding of the RNA. "Folding of the RNA structure competes with formation of the DNA const...

UN successfully tests 'green' pesticide against locusts

...ded RNA. Through specific chemical reactions, they attach two strands of DNA, each resembling one side of a ladder. The two DNA strands spontaneously bind together, then the researchers add magnesium ions to initiate folding of the RNA. "Folding of the RNA structure competes with formation of the DNA const...

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