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Tag: "assess" at biology news

Topical treatment shown to inhibit HIV and herpes simplex virus infection

...bo-controlled study among 20 HIV-infected women to assess the antiviral activity of PRO 2000 in cervicovagin...dy. "We are currently conducting a 14-day study to assess whether or not there is an inflammatory response after repeated applications." ...

Inflammatory molecules released by pollen trigger allergies

...se to injury or infection. The authors now plan to assess whether cells from allergy-prone people are more sensitive to the effects of the pollen-derived compound than those from non-allergic individuals. A better understanding of these molecules and how they work may eventually lead to new approaches to tr...

Mitochondrial DNA mutations play significant role in prostate cancer

... these modified prostate cancer cells into mice to assess theirtumor-forming ability. The prostate cancer cells with the mutant mtDNAsgenerated tumors that were on average seven times larger than theprostate cancer cells with normal mitochondria. Hence, the deleteriousmtDNA mutation greatly enhanced prostat...

Gene variations explain drug dose required to control seizures

...osing scheme that could be tested in the clinic to assess whether pharmacogenetic diagnostics can improve dosing decisions, he added. In particular, it may be clinically relevant to determine whether physicians can safely increase drug doses more rapidly for some patients. Such a trial might also allow phys...

Plant hemoglobins: Oxygen handlers critical for nitrogen fixation

...el legume Lotus japonicus, enabling researchers to assess for the first time the role and importance of these proteins in plants. The results of the study indicate that symbiotic hemoglobins are important for oxygen transport and energy metabolism in plant root nodules. Furthermore, these proteins help to m...

Discovery Could Lead To Novel Approaches In HIV Treatment

...s, has announcedthe development of a new method to assess how well the thymus (an organlocated at the base of the neck) works and the discovery of afunctional abnormality of this organ in HIV-infected individuals. Theteam of investigators led by Dr. Rafick-Pierre Sékaly, professor atUniversité de Montréal, ...

Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells

...ent of disease. More technically put, "To rapidly assess the health of a single mammalian cell," says Gourley, "the key discovery was the elucidation of biophotonic differences in normal and cancer cells by using intracellular mitochondria as biomarkers for disease. This technique holds promise for detecti...

New Treatment Rivals Chemotherapy For Lymphoma, Study Finds

...agged antibody. Nuclear medicine scans are used to assess how quickly Bexxar reaches the tumor and how quickly the radiation disappears from the patient's body. One to two weeks after that initial dose, the patient then receives a custom-tailored therapeutic dose, and therapy is considered complete. The mos...

Asthma gene clusters identified

...ing so, physicians will be in a better position to assess and treat a patient's asthma with greater precision. "As we learn more about disease and how patients respond to treatment, we will eventually be able to develop customized therapy for patients with different gene expression profiles," she said. ...

PET/MRI scans may help unravel mechanisms of prenatal drug damage

Scientists have demonstrated a new way to assess the potentially damaging effects of prenatal drug ...nveniste. The imaging tools could also be used to assess the effects of therapeutic drugs, such as administering synthetic narcotics to pregnant women follow...

NIH Calls on Scientists to Speed Public Release of Research Publications

...d will provide advice on implementation issues and assess progress in meeting the new policy's stated goals. Additional information on the new policy and related documents, including a "Questions and Answers" fact sheet, can be found at: http://www.nih.gov/about/publicaccess/index.htm. ...

New lab technique identifies high levels of pathogens in therapy pool

...lture microorganisms found in such environments to assess the number of pathogen species, an approach that misses many airborne bacteria that are difficult to grow in a lab environment. The new approach allowed researchers to survey more than 1,300 ribosomal RNA genes from different bacteria and fungi in th...

CoPub Mapper: mining MEDLINE based on search term co-publication

...ll gene-gene and gene-keyword pairs determined. To assess gene clustering according to literature co-publication, 150 genes consisting of 8 sets with known connections (same pathway, same protein complex, or same cellular localization, etc.) were run through the program. Receiver operator characteristics (R...

Medical whistleblowers speak out

... are conducted over too brief a period to properly assess safety. There are "blockbuster drugs" out there, said the scientist, that "might be associated with tens of thousands of deaths a year" but this risk "would never be detected in studies of the kind that we routinely submit and are the basis for appro...

Study: 'homemade' gene expression technology unreliable

...we have a relatively reliable method with which to assess gene expression, we can do so reproducibly within ...erstanding of biological mechanisms and methods to assess the actions and effects of drugs and chemicals," said Spencer, who estimates there are "hundreds, if...

One gene links newborn neurons with those that die in diseases such as Alzheimer's

...placed. The researchers used similar techniques to assess UCHL1 in hippocampus and olfactory bulb neurons in mouse brains, areas where neurons are known to undergo spontaneous replacement. They found markedly low levels of UCHL1 in the replaceable neurons of both these regions. "Low levels of UCHL1 appear ...

Oceans more vulnerable to agricultural runoff than previously thought, study finds

...s of phytoplankton." Yaqui Valley agriculture To assess the impact of agricultural runoff on the gulf, the...er colleagues plan to conduct follow-up studies to assess the ecological impact of runoff events in the Yaqui Valley. They also expressed concern about the im...

Elephant seal pups suffer from ocean warming

...he weight, and the survival rate, of the pups. To assess the impact of temperature changes on food availability to elephant seals, Le Boeuf and Crocker monitored the weight of 2750 elephant seal pups over a period of 29 years, from 1975 to 2004, during which the ocean temperature generally increased before...

Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol

...ement, the test may make it possible to accurately assess whether patients are responding to these agents, a...e able to use this system as a molecular marker to assess whether an anti-cancer therapy is working." ABSTRACT # 1670 Sensitivity to Tarceva Depends on CDK2...

Building a protein name dictionary from full text: a machine learning term extraction approach

...s dictionary match SwissProt description lines. We assess the quality of the dictionary by studying its protein name recognition performance in full text. Conclusions This dictionary term lookup method compares favorably to other published methods, supporting the significance of our direct extraction approa...

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