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Tag: "assembling" at biology news

Cellular message movement captured on video

...hesize that this process enables cell migration by assembling new focal adhesion sites in the direction of cell movement and disassembling them on the trailing side of the cell. Researchers are applying the fluorescence-labeling technique to the many other signaling and structural proteins found predominantly a...

Anthrax paralyzes immune cells with lethal toxin, UF research shows

...dual cell, you can't figure out where the actin is assembling and what's controlling it. But Listeria seems to use the same pathways that a cell uses to crawl. So anything that blocks Listeria we predict would also block neutrophils from crawling. And that's what we found."...

DOE JGI sets 'gold standard' for metagenomic data analysis

... puzzle pieces of DNA. "One of the problems in assembling metagenomes," said Mavrommatis, "is that you end up with large fragments of unknown accuracy and a substantial number of sequences that fail to fit onto those larger fragments. On many occasions, this information is not taken into account, depriving...

Horse genome assembled

...(BAC) end sequences, which provide continuity when assembling a large genome sequence, were contributed to the horse sequencing project by Ottmar Distl, D.V.M., Ph.D. and Tosso Leeb, Ph.D., from the University of Veterinary Medicine, in Hanover, Germany and Helmut Blöcker, Ph.D., from the Helmholtz Centre for I...

Destructive enzyme shows a benevolent side

...er protein called TIA-1, a key protein involved in assembling stress granules. This interaction draws the enzyme-mRNA complex into stress granules. But the researchers were unable to detect any sign that the message was destroyed. "The fact that we don't see an acceleration of mRNA decay suggests that som...

Researchers make nanosheets that mimic protein formation

...s and nanoparticles, and this is very exciting for assembling materials from the bottom up for a whole slew of applications ranging from drug delivery to energy," said Sharon Glotzer, professor of chemical engineering and materials science and engineering. Glotzer and Nicholas Kotov, associate professor of c...

Study offers innovative profile of enzyme that aids tumor growth

.... "The success of our study opens the door to assembling the full range of enzymes into both metabolic and signaling networks contributing to complex pathologies like cancer," Cravatt said. "This could lead to the discovery of new markers for diagnosis and targets for treatment." ...

Researchers show how brain decodes complex smells

...s each scent component like a jigsaw puzzle piece, assembling the signals until it recognizes the picture is a cookie? To find answers, the Duke researchers exposed mice to different odors and measured response of neurons across the olfactory bulb with intrinsic signal imaging. The imaging technique maps brain...

UT Southwestern researchers find gene mutation that leads to 'broken hearts'

... synthesis plays a previously unrecognized role in assembling the heart. The same mechanism is likely to be involved in human-heart development," said Dr. Olson, director of the Nancy B. and Jake L. Hamon Center for Basic Research in Cancer and the Nearburg Family Center for Basic Research in Pediatric Oncology...

MIT researchers build tiny batteries with viruses

...illions of identical copies of the virus to use in assembling our batteries. "For the metal oxide we chose cobalt oxide because it has very good specific capacity, which will produce batteries with high energy density," meaning it can store two or three times more energy for its size and weight compared to pre...

Major WHO study concludes calcium supplements can reduce complications during pregnancy

...ulate flap motion in this manner. Lin is currently assembling a team of researchers for this project. In the meantime, while Perryman is completing a postdoctoral fellowship, he is learning about protein engineering with Mayo, so that he can apply it to the design of therapeutic proteins as well as biomolecular...

Computer simulation hints at new HIV drug target

...ulate flap motion in this manner. Lin is currently assembling a team of researchers for this project. In the meantime, while Perryman is completing a postdoctoral fellowship, he is learning about protein engineering with Mayo, so that he can apply it to the design of therapeutic proteins as well as biomolecular...

UW scientists unravel critical genetic puzzle for flu virus replication

...lls. What Kawaoka found was that the viruses were assembling their infectious genetic elements in a systematic fashion. Virologists have long debated whether the RNA segments in flu viruses assembled at random into the virions or were somehow incorporated into the infectious particle in an organized way. The ...

DNA self-assembly used to mass-produce patterned nanostructures

...e researchers also may explore how their method of assembling tiles can be used create biological structures that could act as tiny sensors. ...

'Cookbook recipes' would cure disease with nontoxic DNA delivery systems

...nding some of the physics, we now have recipes for assembling delivery systems with different structures, which can have intrinsically different, controllable DNA delivery efficiencies," Wong said. "We found that the same family of structures are generated for many different ions." Gene therapy is one of the m...

Researchers seek to discover what really happens when a virus enters the body

... developed "a method to remove the grid created by assembling the montage of sub-images. Our method ?based on a model we developed that reflects the physics of fluorescent microscopy ?also estimates and corrects the effect of the microscope's uneven illumination and the markers' spectral overlap," Bell explains...

Biologists determine genetic blueprint of social amoeba

... long, that proved useful for other researchers in assembling the genetic sequences of Dictyostelium's genome. Another UCSD biologist involved in the genome effort, Christophe Anjard, an assistant project scientist in Loomis' laboratory, analyzed families of Dictyostelium genes and uncovered relationships with ...

Shutting down the HIV assembly line

...its way from this site to the cell membrane before assembling into particles. Although many studies have demonstrated that Gag is present in the late endosome and have focused on particle assembly at that point, none have tackled how the Gag protein gets there in the first place. The current work fills this ga...

U-M scientists find genes that control growth of common skin cancer

...arious epithelial celltypes, ultimately capable of assembling fully-formed hair follicles.These results suggest that BCCs contain cells capable of multi-lineagedifferentiation, similar to normal hair follicle stem cells from whichthey may arise.If the results of this study are applicable to human BCC, the disco...

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