How many genes does it take to learn? Lessons from sea slugs
...r neurodegenerative diseases. "The authors have assembled a tremendous amount of data on gene transcripts associated with neuronal signaling pathways in Aplysia that sheds new light on evolutionary relationships of this very ancient and highly successful marine animal," said Dennis Steindler, Ph.D., executi...World's smallest cancer detection device
...sed successfully in animals. The microchip will be assembled from nanoscale components so that several different functions can be carried out within a very small package. The goal: to implant these tiny microchips ?just two to three cells in diameter and a tenth of a millimeter in length ?in human tumors, wher...The first tree genome is published: Poplar holds promise as renewable bioenergy resource
...lar is the most complex genome to be sequenced and assembled by a single public sequencing facility and only the third plant to date to have its genome completely sequenced and published. The first, back in 2000, was the tiny weed, Arabidopsis thaliana, an important model for plant genetics. Rice was the secon...Engineer ramps up protein production, develops versatile viral spheres
...igurations to make novel materials. Materials from assembled capsids could be light, strong and biodegradable, Swartz says. Piggybacking vaccines on capsids may provide safer and more effective vaccinations than current methods, Swartz says. Most vaccines today work by introducing dead or weakened copies of ...Nanoparticle assembly enters the fast lane
...d. The research team probed the synthesized and assembled nanosystems with multiple imaging techniques, using beams of light and electrons as well as high-intensity x-rays at Brookhaven's National Synchrotron Light Source. The scientists look to further improve the controllability of the system, focusing ne...Protein splicing upsets the DNA colinearity paradigm
...sequences are removed and the coding sequences are assembled in a linear fashion to form the template for translation from RNA to protein. "Until now it was thought that colinearity of DNA and protein sequences was only interrupted by RNA splicing," says LICR's Dr. Benoit Van den Eynde, the study's senior a...Living view in animals shows how cells decide to make proteins
...man development, and the order in which its RNA is assembled can alter an animal’s development. As a model system to study, the scientists genetically created a "glowing" mouse. The mouse carried in its FGFR2 gene a green fluorescent tag that would glow when a common type of silencer, called an "intronic si...... Institut Curie. The original images obtained and assembled in twelve video sequences are the result of close collaboration between a specialist in two-photon microscopy, Luc Fetler, an INSERM scientist in the CNRS/Institut Curie "Physical Chemistry Curie" Unit1, and immunologists, notably Alexandre Boissonna...Scientists unravel clue in cortisol production
... the cells to make more cAMP. Then as the proteins assembled on the DNA, they tested the cells at different intervals in order to get a snapshot of which proteins were interacting, both with each other and the DNA and in which order this occurred. Then they mutated the proteins to stop them from fulfilling the...Mercury contamination of fish warrants worldwide public warning
...by many of the world's leading mercury scientists, assembled into four expert panels, to review and synthesize the major mercury science findings. Every member of all four scientific panels endorsed the declaration, he said. Wiener added that all 1,150 participants at the conference were invited to express t...Woman's Day and For Womens of Science
...by many of the world's leading mercury scientists, assembled into four expert panels, to review and synthesize the major mercury science findings. Every member of all four scientific panels endorsed the declaration, he said. Wiener added that all 1,150 participants at the conference were invited to express t......ned to create image files or "virtual slides," and assembled like tiles into composite images. The maps have a resolution of better than half a micrometer per pixel, or 55,000 dots per inch, with virtual slides approaching 30 gigabytes in size each. ...DNA repair proteins monitored at double-strand break
... eye view of the human cell’s DNA repair kit as it assembled on a double-strand break to link together the broken ends. Double-strand breaks are ruptures that cut completely across the twisted, ladder-like structure of DNA, breaking it into two pieces. Using a technique developed specifically for this projec...Scientists identify prion's infectious secret
...c yeast prion, one that another research group had assembled from pieces of both the baker’s yeast and the pathogenic fungi prion. Earlier studies had shown that this synthetic prion could cross the species barrier but did not identify the mechanism. Tessier found that this synthetic prion contained two recogn...Anthrax paralyzes immune cells with lethal toxin, UF research shows
...ing them to the center of the cell, where they are assembled into filaments. "We've discovered that through this pathway, lethal toxin blocks the function of a protein that regulates how actin assembles," said Southwick, who believes his findings may also explain how anthrax paralyzes other types of cells, ...How brain pacemakers erase diseased messages
...l pattern of activity seen in people with tremors, assembled a group of these model cells and watched what would happen when the cells were electrically stimulated at various rates and intensities. In addition to showing how the therapy works, their model of neurons in action also revealed that stimulation ...Exploring the dark matter of the genome
...kilobases long. Contiguous lengths of sequence are assembled by matching overlaps of these fragments. With euch...gments like transposons and single-copy genes were assembled by comparing numerous copies with unique or sufficiently distinctive sequences. The assembly was che......d previously reported that paxillin can be rapidly assembled and disassembled, and they hypothesize that this process enables cell migration by assembling new focal adhesion sites in the direction of cell movement and disassembling them on the trailing side of the cell. Researchers are applying the fluorescenc...