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Tag: "assembled" at biology news

DNA Molecules Used To Assemble Nanoparticles

...cles together. Nanometer-scaled dendrimers can be assembled in many configurations by using attached lengths of single-stranded DNA molecules, which naturally bind to other DNA strands in a highly specific fashion. "With this approach, you can target a wide variety of molecules---drugs, contrast agents---to ...

Whole genome fine map of rice completed

...aft sequence published in 2002. The fine maps were assembled with whole genome shortgun approach. Through searches of 19079 full length cDNA, 97.7% of complete genes were found in the two genomes. After adjusting for residual errors of predictions with EST data, the number of genes is estimated to be between 3...

The transparent organism: EMBLEM and Carl Zeiss give labs a unique look at life

...-processing step, one or more stacks of images are assembled into a high-resolution film. Another advantage of SPIM is that the specimen is kept alive in a liquid-filled chamber, allowing scientists to track developmental processes like the formation of eyes and the brain in embryonic fish or other model orga...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

...which the most functionally important proteins are assembled into machinery from one species to another is also, to a certain degree, conserved," said Ideker. "The circuitry is not exactly the same. In fact, there are striking differences that warrant more investigation." The team included Roded Sharan, a com...

Reservoirs may accelerate the spread of invasive aquatic species, researchers say

...oreover, they typically contain unstable, recently assembled communities of stocked fish. An ecological hypothesis known as the fluctuating resource availability hypothesis suggests that these characteristics will enhance the susceptibility of reservoirs to invasion. Because reservoirs are more saline that fre...

Researchers make surprise discovery that some neurons can transmit three signals at once

...ew light on how inhibitory synapses evolve and are assembled into functional circuits in the developing brain," he added. Many brain disorders, like epilepsy, schizophrenia and depression, involve deficits that prevent normal inhibition of cells. Dr. Kandler's research could eventually provide insight into th...

Stealth Worms May Improve Insect Pest Control

...evolutionary associations, called phylogenies, are assembled to show how the nematodes have evolved in relation to each other and how they are related in a geographic region to affect similar hosts. "We always look at the insect and nematode interactions in the laboratory first, then go out and look at the cr...

Gov't Creates Gene Database of Normal Human Tissues

...s. To create these fingerprints, Khan and his team assembled a complementary DNA (cDNA) microarray, using a pair of glass slides on which thousands of known genes have been printed in tiny spots. Cells can be tested by manipulating them so that genes activated in the cell will match up with the known gene samp...

Scientists use manufacturing methods to reconstruct mastodon

...forgettable." The skeleton in the exhibit will be assembled from the fiberglass casts so that researchers can continue studying the real bones, which are on loan to the museum from the Buesching family. When complete, the exhibit will be significant for a number of reasons, Fisher said. "To my knowledge it w...

Life detection instrument passes key test on road to Mars

...ted with the Mars Organic Detector, which is being assembled by scientists directed by Frank Grunthaner at the Jet Propulsion Laboratory (JPL) in Pasadena together with Jeff Bada's group at UC San Diego's Scripps Institution of Oceanography. Skelley, a graduate student who has been working on amino acid detec...

Scripps research scientists solve structure of a critical innate immune system protein

...shows how the repeating leucine-rich repeat motifs assembled in TLR3 in never-before-seen detail. The portion of TLR3 the scientists solved lies on the outside of the membrane and reveals the potential binding site for its ligand, double-stranded RNA. TLR3 forms a large horseshoe shape that contacts with a ne...

Self-assembled DNA buckyballs for drug delivery

...e, hollow buckyballs are also the first structures assembled from "dendrimerlike DNA." If three strands of artificial DNA are created such that portions of each strand are complementary to portions of another, the three strands will bind to each other over the complementary portions, creating a Y-shaped molecu...

Unexpected lock and key mechanism found for the assembly of tumor blood vessels

...In addition, knowing how blood vessels are finally assembled could help lead to effective ways to stop the proliferation of cancer cells by cutting off their nutrient supply, Varner added. Drs. Varner and Parker are currently in discussions with pharmaceutical companies to test integrin inhibitors in cancer cl...

Secrets to antibody's success against West Nile Virus surprise scientists

...re copies of the genetic material that can then be assembled into new viral particles or virions and sent out to infect other host cells and reproduce. But with the viral reproduction process blocked by the antibody, scientists suspect that the host cell eventually destroys the virion. Fremont and colleague...

Hopkins scientists uncover 'tags' that force proteins to cell surface

...ins to the cell surface means the proteins weren't assembled properly in the cell, Li says that how and where p...proteins are in the cell nucleus, and proteins are assembled in a nearby "factory" in the cell. Also, scientists have long known that proteins prefer to stay put...

UIC developing drug for SARS

..., build protease inhibitors, like the prototype he assembled earlier, through what is called structure-based drug design. He will create computer images of each enzyme coupled with compounds anticipated to obstruct the pockets, revealing whether and how tightly the molecules fit in the space. If the fit is poo...

New discovery blurs distinction between human cells and those of bacteria

... they are built from thousands of protein subunits assembled into a shell-like architecture, are an important component of bacteria. I expect there will be a much greater focus on them now." Yeates' Science paper reveals the first structures of the proteins that make up these shells, and the first high-resolu...

MSKCC researchers uncover structure of key protein complex in cells

... believe the protein complex they have observed is assembled at nuclear pore complexes, portals that connect the nucleus with the cytoplasm beyond. These conduits permit the transfer of information both to and from the nucleus, and are vital to proper cell function. "The next step in this research is to probe...

Nighttime Dying Linked To Sleep Apnea From Brain Cell Loss

... they are built from thousands of protein subunits assembled into a shell-like architecture, are an important component of bacteria. I expect there will be a much greater focus on them now." Yeates' Science paper reveals the first structures of the proteins that make up these shells, and the first high-resolu...

Field tested: Grasslands won't help buffer climate change as carbon dioxide levels rise

... they are built from thousands of protein subunits assembled into a shell-like architecture, are an important component of bacteria. I expect there will be a much greater focus on them now." Yeates' Science paper reveals the first structures of the proteins that make up these shells, and the first high-resolu...

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