New, automated tool successfully classifies and relates proteins in unprecedented way
... a cellimage. SLFs measure both simple and complex aspects of proteins, suchas shape, texture, edge qualities and contrast against backgroundfeatures. Like fingerprints, a protein's SLFs act as a unique set ofidentifiers. Using a set of established SLFs, Murphy then developed acomputational strategy for auto...Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
...implies that E. histolytica may have re-engineered aspects of its metabolism," says Loftus, citing the protist's loss of some genes and its apparent gain of other bacterial-like genes through lateral transfer. "This study will provoke interest in what secrets may lie undiscovered in the sequences of other su...New Clues Add 40,000 Years to Age of Human Species
... back our time of origin," he adds, “most cultural aspects of humanity appear much later in the record—only 50,000 years ago—which would mean 150,000 years of Homo sapiens without harpoons, music, needles or even most tools. This is another mystery yet to be solved," he said. When Richard Leakey, F. Clark ...Scientists collaborate to assess health of global environment
...s. A substantial body of work addressing specific aspects of the assessment will follow this month's release of the global synthesis report. A report on global biodiversity will be available in May; a report on desertification is due out in June; and reports related to wetlands, the role of the private sect...New research questions basic tenet of neuron function
... study. Neurotransmitters regulate many different aspects of mood, cognition and behavior, such as emotional state, reactions to stress, pain, and the physical drives of sleep, appetite and sexuality. A better understanding of such fundamental mechanisms of neurotransmitter release will aid researchers in ...Development of portable infectious disease detector
...ut the size of a coffee cup.One of the cost-saving aspects of the design was to keep thefluid-handling components separate from the microelectronics. Theresulting device is considerably larger than comparable lab-on-a-chipsystems but it is also much less expensive. "That's one of theappealing features about ...Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers
...'d like to expand our present model to explain all aspects of insect breathing. And we'd like to examine insects that do not show this pattern -- for example, desert beetles. While we have shown that insects monitor oxygen precisely, we do not know how that happens or which tissues and cells are involved. On...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
...ommercial, political, ethical, legal, and societal aspects of thisresearch."...New insight into people who 'see' colors in letters and numbers
...dy of synesthesia, we are able to examine specific aspects of the synesthetic experience that previous studies have not been able to address." Edward M. Hubbard, A. Cyrus Arman, Vilayanur S. Ramachandran, and Geoffrey M. Boynton: "Individual Differences among Grapheme-Color Synesthetes: Brain-Behavior Corre...New RNA polymerase discovered in plants
...is a distinct RNA polymerase, they still have many aspects of Pol IV to unravel. "We know what happens when its gone, but not how it behaves, at this point," he said. "We don't know its template, or what kind of RNA ?long or short ?it makes. Presumably, because it is inherently different from the other RNA ...World's largest rainforest drying experiment completes first phase
...ree growth, tree death, leaf production, and other aspects of forest behavior, researchers compared this dry plot of forest with a similar plot, from which rainfall was not excluded. These two forest plots were compared for a year prior to installation of the plastic panels to register any differences in beh...Opposing fat metabolism pathways triggered by a single gene
...ear hormone receptor nhr-49 controls two different aspects of fat metabolism, which interact to form a feedback system controlling the consumption and composition of fats in the nematode. Using RNAi to suppress gene expression, the researchers discovered that when nhr-49 was absent, the lifespan of the nema...Multiple Campylobacter Genomes Sequenced
...species in genes that are likely to be involved in aspects of bacterial virulence, such as adherence, motility, and toxin formation, are all detailed by Fouts et al., who also describe a new putative Campylobacter virulence locus. Further work is needed to relate these genomic differences to functional diffe...UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders
...ical disorders: UCLA researchers are studying many aspects of the roles that stem cells may play in healing neurological disorders, including stroke, spinal cord injury, brain tumors, multiple sclerosis and genetic diseases. Future studies will include investigation of stem cell biology and development, as w...A frog's life is food for thought
...e and were fed regularly. "I compared the various aspects of their gut biology and physiology," she said. "We put animals into aestivation and woke them up and fed them to find out how quickly they got everything going again." Ms Cramp's results show that animals can maintain the functional capacity of th...Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert
...e, leads rover development and field investigation aspects of the project. Nathalie Cabrol, a planetary scientist at NASA's Ames Research Center and the SETI Institute, leads the science investigation. Life is barely discernable over most areas of the Atacama, but the rover's instruments were able to detect...Microbial forensics: The next great forensic challenge
...loitative, fully validated methods and uses in all aspects of the forensic investigative process," Murch said. "This ranges from sample collection to interpretation of results, while achieving full integration into investigation, prosecution, intelligence, and decision making. Since the results of a microbia...Love's all in the brain: fMRI study shows strong, lateralized reward, not sex, drive
...ave more to do with motivation, reward and "drive" aspects of human behavior than with the emotions or sex drive. Brain systems were activated that humans share with other mammals. So the researchers think "early-stage romantic love is possibly a developed form of a mammalian drive to pursue preferred mates,...Study reveals new technique for fingerprinting environmental samples
...ach employed in the study shares similarities with aspects of the Human Genome Project research. In the early 1990s, incomplete fragments of human genes called Expressed Sequence Tags (ESTs) were used as diagnostic fingerprints for human tissues to determine their unique features and disease status. These in...... components. They play key regulatory roles in all aspects of eukaryotic cell physiology and their deregulation is associated with a number of pathological conditions, which make kinases key targets in drug discovery efforts, primarily in oncology. This collection is unique because clones in the collection ...