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Tag: "artery" at biology news

Implanted Devices Detect High-Risk Heart Failure Patients

...y causes include infections of the heart, coronary artery disease, high blood pressure, previous heart attacks and valve problems. An estimated 4.7 million Americans suffer from the condition, with 400,000 new cases reported each year. Roughly one-half of patients die within five years of diagnosis. Althou...

Rush Physicians Using Gene Therapy For Heart Patients With Moderate To Severe Chest Pains Who Do Not Benefit From Other Treatments

...ardiac catheter threaded into the heart from a leg artery or a placebo delivered using the same method. As r...n people in the United States suffer from coronary artery disease. Many patients receive medications to increase blood flow but nearly 500,000 angioplasties a...

International HapMap consortium expands mapping effort

...iven disease, such as type II diabetes or coronary artery disease, researchers can use the HapMap to compare the genetic variation patterns of a group of people known to have the disease with a group of people without the disease. Finding a certain pattern more often in people with the disease identifies a ...

Vascular structure and function improve with diet and exercise

...olesterol disorders such as dyslipidemia. Carotid artery distensibility was the only structural factor that significantly improved. It rose about 16 percent. Petrella said that the other factors may improve as patients are followed for one year. One in three American adults has high blood pressure and two...

Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries

... the arteries," occurs when the inside walls of an artery become thicker and less elastic. This narrows the...le. Fatty buildups occur on the inner lining of an artery and gradually thicken into a plaque. As plaque grows, it narrows the artery more and more. When the ...

Insight into natural cholesterol control suggests novel cholesterol-lowering therapy

...illion people each day to protect against coronary artery disease and reduce the incidence of heart attacks--limit cholesterol synthesis by inhibiting reductase function, he said. As a result, cells take up more cholesterol from the bloodstream, lowering its concentration there. However, inhibition of redu...

Mystery Blood Vessel Disorder Implicated In 'Mini' Strokes

...eurysms, a potentially fatal weakening of the main artery that carries blood out from the heart. In an arti...en the diameter of the basilar artery, the cranial artery most often affected in dolichoectasia, and the severity of small vessel disease. "This study is the...

Nano-bumps could help repair clogged blood vessels

...y coated, blood cells passing through the repaired artery come into contact with the metal and recognize it as foreign." Findings will be presented on April 28 during the Society for Biomaterials' 2005 Annual Meeting and Exposition in Memphis, Tenn. The work was conducted by graduate student Saba Choundhar...

Bone marrow stem cells may heal hearts even years after heart attacks

...ion disturbances in patients with chronic coronary artery disease after myocardial infarction, even many yea... were infused through a catheter into the coronary artery where the patient's heart attack occurred. "The main results were at least threefold: an improvemen...

UT Southwestern researchers unravel control of growing blood vessels

...lood vessels is involved in hypertension, coronary artery disease, tumors called leiosarcomas and other conditions. "By understanding this detailed mechanism, it is now possible to begin to design therapies to interfere with it and thereby potentially prevent various vascular disorders in humans," said Dr....

Researchers show how air pollution can cause heart disease

...ered air. In cross sections taken from the largest artery in the body--the aorta--mice on normal diets and exposed to PM2.5 had arteries 19.2 percent filled with plaque, the fatty deposits that clog arteries. The arteries of those breathing particle-free air were 13.2 percent obstructed. Among high-fat diet...

Bare metal stents deliver gene therapy to heart vessels with less inflammation in animal studies

...cible nitric oxide synthase (iNOS), in the carotid artery studies, because of iNOS's ability to control cell damage in blood vessels. "However, in further studies, one might use a combination of therapeutic genes or different gene vectors, for even better results," said Dr. Levy. Metallic implants are alre...

Feds give researchers ok for safety test of adult stem cells in patients with heart disease

...es of patients suffering chronic ischemic coronary artery disease, a condition in which one or more of the p...dates for angioplasty, stent placement or coronary artery bypass grafting (CABG). Dale Adler, M.D., vice chair of medicine at Case and UHC, will lead this st...

Genetic key to growth of new arteries is identified

... the growth of new arteries when the femoral (leg) artery is blocked. The team also identified and described, for the first time, the specific DNA sequences of the MMP2 gene that are expressed when new arteries are grown. The study appears in the November 8 issue of the Proceedings of the National Academ...

Stem cell mobilization therapy appears to be ineffective in repairing damage caused by heart attack

...e in the risk of restenosis (narrowing again of an artery after treatment) or major adverse cardiac events was observed with G-CSF treatment," the authors write. "The REVIVAL-2 trial had a cohort that was larger than all 3 previous trials taken together and had a relatively long follow-up period based on s...

Ernst Mayr's theory illustrated in genetic epidemiology studies

...g his own genetic epidemiology studies of coronary artery disease (CAD). "These recent results really show that Mayr's ideas were correct," said Templeton. "His theory has been empirically supported very well." But first, the background. Mayr thought that founder events were very important in the orig...

Aspirin reduces cardiovascular risks in men and women -- but differently

...otal of 95,456 patients, none of whom had coronary artery disease. Of that total, 51,342 were women. The trials all involved the comparison of low-dose aspirin versus placebo for the primary prevention of cardiovascular disease. The analysis revealed that aspirin conferred a 12 percent reduction in risk in...

Measuring artery repair cells could become new heart disease test

...d be used to assess a patient's degree of coronary artery disease or risks for suffering a heart attack, and... EPC levels correlated with the degree of coronary artery disease. Patients with no coronary artery disease had about 70 percent more EPCs than those who had ...

Bone and cartilage growth to blame for heart valve disease

... States population, and is second only to coronary artery disease as a cause for open heart surgery. Heart v...eated with medications similar to that of coronary artery disease. "As with the majority of people in the field who hear about this research, I was surprised...

Statins have neutral effect on risk of cancer

...s for primary and secondary prevention of coronary artery disease. In these trials, statins reduced the risk of a first myocardial infarction (heart attack) and overall mortality. With long-term follow-up and collection of cancer data in a majority of studies, insight into the risk of cancer among statin...

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