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Tag: "arrest" at biology news

Buying Time Through Hibernation on Demand

...loss injury, hypothermia, malignant fever, cardiac arrest and stroke. The potential medical benefits also i...ork have demonstrated the ability to metabolically arrest ?and subsequently re-animate ?such model organisms as yeast and worms, as well as the embryos of fru...

U-M team recovers ancient whale in Egyptian desert

...loss injury, hypothermia, malignant fever, cardiac arrest and stroke. The potential medical benefits also i...ork have demonstrated the ability to metabolically arrest ?and subsequently re-animate ?such model organisms as yeast and worms, as well as the embryos of fru...

No small feat: First ever gene therapy success for muscular dystrophy achieved

...ystrophy we're not likely to be able to completely arrest or cure CMD," added Chungping Qiao, M.D., Ph.D., the study's first author and a research associate fellow in Dr. Xiao's lab. Future directions for research include finding a way to engineer the laminin alpha-2 gene. For this study, the authors chose...

Polymer gel can block toxic leakage problem in gene therapy

...rs have devised a potentially patentable method to arrest toxic leakages of genetically engineered viruses that have plagued attempts to use gene therapy against cancerous tumors. The problem has been that viruses carrying anti-tumor genes have tended to leak from tumors, proving toxic to other body tissues...

Image of myosin-actin interaction revealed in cover story of Molecular Cell

...ble condition resulting in death by sudden cardiac arrest in otherwise healthy young adults. Contributors to this work include: Niels Volkmann, Ph.D., assistant professor and first author on this publication, Dorit Hanein, Ph.D., associate professor, Hong-Jun Liu and Larnele Hazelwood from the Burnham Inst...

Study: Paramedics save more lives when they don't follow the rules

...al rates following the most common form of cardiac arrest increased three-fold when emergency medical person...ator to do its analysis takes time ?time a cardiac arrest victim doesn't have," said Gordon A. Ewy, MD, director of the Sarver Heart Center and co-author of t...

Tramiprosate (Alzhemed? preclinical results published in Neurobiology of Aging

...ifying effect of this product candidate to slow or arrest the progression of AD. While the paper issue of the publication will be available in a future issue of Neurobiology of Aging, an electronic version of the article entitled "Targeting soluble Aβ peptide with Tramiprosate for the treatment of brain ...

Clot-busting drug helps revive cardiac arrest patients

.... The pilot study involved patients with cardiac arrest who didn't respond to standard therapy. Of 50 pati...ckly follows. The standard treatment for cardiac arrest is Advanced Cardiac Life Support (ACLS) measures, which include cardiopulmonary resuscitation (CPR),...

Prototype just-in-time medical device enables untrained bystanders to save lives

... About 300,000 people a year suffer sudden cardiac arrest in the United States. Sometimes the victim's life ...y increase and survival chances for sudden cardiac arrest victims could be significantly improved. ...

Turning a cellular sentinel into a cancer killer

... that overexpressing p53 at very high levels could arrest or kill tumors, said Lowe. "But at such high level... apoptosis. Instead the cells underwent cell cycle arrest with features of senescence." Jacks said that he and his colleagues found no evidence that restori...

Small molecule dervived from Rb2/p130 could act as cancer therapeutic

...n leads to inhibition of cdk2 activity, cell cycle arrest and tumor growth reduction in vivo," in the March 22 issue of the journal Oncogene ( http://www.nature.com/onc ). Rb2/p130 was discovered in the early 1990s by Antonio Giordano, director of the Sbarro Institute ( http://www.shro.org ) and the Center...

Finnish scientists discovered a new approach to treat virus-induced lymphomas

...ells from tumor development by inducing cell-cycle arrest or apoptosis via a complex signal transduction network referred to as the p53 pathway. TP53 gene is mutated or deleted in 50% of all malignant tumors. A recently discovered strategy for p53 activation targets the interaction of p53 with its negative ...

New protein inhibitor impedes growth of cancerous cells

...odel for human tumor growth. BI 2536 caused growth arrest and cell death in cell lines derived from a variety of human cancers, and it inhibited the growth of human tumor grafts in mice, resulting in the death of tumor cells and regression of large tumors. The authors report that BI 2536 has now been brough...

Study shows big power of small RNAs, not just proteins, in halting cancer

...earch laboratories has not only found that p53 can arrest the growth and even eradicate cancers, but we’ve revealed something very surprising about what makes this pathway so powerful,” said Hannon. CSHL research published by Nature earlier this year, concluded that even in the latest stages of cancer, reac...

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