Neurotransmitters signal aggressive cancer, offer potential for early diagnosis
... in the mouse tumors using GeneChips, miniaturized arrays of gene sequences, to obtain information about how active each gene in tumors is. They combined the mouse data with parallel data from 182 human tumors. Then, the gene-activity data was fed into sophisticated software that supplied the researchers w...Researchers learn how blood vessel cells cope with their pressure-packed job
...ength, 60 times per minute) produced intracellular arrays of parallel "stress fibers" in a few hours. The tests were performed on endothelial cells lining the aorta of a cow, but the endothelial cells of the human aorta are expected to react similarly. The stress fibers were made of actin, a fibrous protei...Sensors, a smart dose of medicine for cancer treatment
... here at the Tyndall Institute," says Jaksic. The arrays are extremely accurate and can track radiation at ...dose actually delivered. "The two modular 2D diode arrays are placed in orthogonal positions inside the phantom, so we have data in 3D over time," says Jaksic...UC Berkeley researchers create a biologically-inspired artificial compound eye
...dimensional optical systems to integrate microlens arrays ?thousands of tiny lenses packed side by side ?with self-aligned, self-written waveguides, that is, light-conducting channels that themselves have been created by beams of light, said Lee, the Lloyd Distinguished Professor of Bioengineering at UC Ber...University of Utah to help build bionic arm
...ultimately is chosen for the bionic arm, electrode arrays will be implanted in some or all of the four major... The Utah team is focusing on implanting electrode arrays in nerves in the residual limb. "The nerve is potentially an excellent site for communicating with...Both alcoholism and chronic smoking can damage the brain's prefrontal cortex
...ultimately is chosen for the bionic arm, electrode arrays will be implanted in some or all of the four major... The Utah team is focusing on implanting electrode arrays in nerves in the residual limb. "The nerve is potentially an excellent site for communicating with...Berkeley researchers lay groundwork for cell version of DNA chip
...alysis, we hope to make cell chips (self-assembled arrays of cells on a thumbnail-sized chip) using our DNA-... said, is to develop procedures for making complex arrays of cells quickly. The researchers also need to demonstrate that devices based on this cell-adhesion...Most human-chimp differences due to gene regulation ?not genes
...tionary time. The next steps are to look at larger arrays of genes and to focus on other tissue types. ...Mitochondrial DNA sequencing tool updated
...chnological platform for laboratories to customize arrays more attuned to their research interests. In 2004, Dr. Anirban Maitra and his colleagues at Johns Hopkins did exactly that with the MitoChip v1.0. In addition to nitty-gritty technical innovations that vastly improved the rate and speed of the chi...Nanowire arrays can detect signals along individual neurons
...nvasive and harmful, and microfabricated electrode arrays are too bulky to detect activity at the level of individual axons and dendrites, the neuronal projections responsible for electrical signal propagation and inter-neuron communication. By contrast, the tiny nanowire transistors developed by Lieber ...Sandia work launched on space shuttle shows live cells influence growth of nanostructures
...uerque, N.M. -- Far above the heads of Earthlings, arrays of single-cell creatures are circling Earth in nanostructures. The sample devices are riding on the International Space Station (courtesy of Sandia National Laboratories and the University of New Mexico, NASA and US Air Force) to test whether nanos...Ring-like formations in drying DNA drops could affect hybridization studies
...e effects should be accounted for in the design of arrays in which DNA droplets are sequentially deposited onto a glass surface for hybridization studies, the researchers report. "Without optimization of the wetting conditions, it is possible to miss all the DNA in the ring stain of a dried droplet, result...Lack of key enzyme associated with development of rare tumor
...In conducting the study, the researchers used gene arrays to analyze the DNA of patients with a rare tumor of the adrenal glands, known as micronodular adrenocortical hyperplasia, explained the study's senior author, Constantine Stratakis, M.D., D(Med)Sc, Chief of NICHD's Section on Endocrinology and Geneti...MIT designs portable 'lab on a chip'
...rent (AC) applied at closely spaced microelectrode arrays on the channel floor. Existing AC electro-osmotic pumps, however, are too slow for many applications, with velocities below 100 microns per second. In the new system, known as a three-dimensional AC electro-osmotic pump, tiny electrodes with raise...Researchers make nanosheets that mimic protein formation
...s basic building principle for producing organized arrays of biomolecules with controlled geometrical and physicochemical surface properties," Glotzer said. "In the fabrication of functional nanoscale materials and devices, self-assembly offers substantial advantages over traditional manufacturing approache...Scientists win grants to develop $1,000 genome sequencing technology
...t developing a method for fabricating high-density arrays of nanoparticles, with one fragment of DNA attached to individual nanoparticles in the arrays. The investigators will attempt to demonstrate that more than 1 billion individual DNA molecules can be sequenced simultaneously....Robotic whiskers can sense three-dimensional environment
...ted to the brain and to develop artificial whisker arrays for engineering applications. Mitra J. Hartmann...f Hartmann's graduate students, have now developed arrays of robotic whiskers that sense in two dimensions, mimicking the capabilities of mammalian whiskers. ...NHGRI aims to make DNA sequencing faster, more cost effective
...s to develop a method for fabricating high-density arrays of wells with sub-micrometer dimensions for orderi... This team will aim to develop highly integrated arrays of nanopores that can be fabricated by lithographic methods, along with on-chip silicon-based electr...Molecular motors and brakes work together in cells
...fission yeast cells, showed that stable end-to-end arrays of microtubules can be achieved by a balance between the sliding by a molecular motor called klp2p and the braking of a microtubule-associated protein (MAP) called ase1p. Specifically, they showed that a preexisting "mother" microtubule acts as a pla...NIH neuroscience microarray consortium launches high-throughput genotyping services
...e Affymetrix platform and uses the Affymetrix exon arrays to look at splice variants, in addition to the new Illumina expression and genotyping capabilities. The principal investigator at Yale, Shrikant Mane, says that the "Illumina platform provides an important complement to the other technologies cur...