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Purdue proves concept of using nano-materials for drug discovery

...ciate professor of chemical engineering. "What we are reporting now is a proof of concept," said Lee, on...of the journal Langmuir. The two other researchers are Zhigang Wang, a postdoctoral fellow at Purdue; and Richard Haasch, a research scientist at the Unive...

In the sea slug's defense against lobsters, confusion is key

...tacks actually work against their intended targets are not well understood by researchers. New work has n...retion contains large quantities of chemicals that are also found in the food of spiny lobsters and that indeed these chemicals serve to activate nervous-s...

Scientists discover the cellular roots of graying hair

Few things about growing older are asinevitable and obvious as “going gray,?yet scien...he wrong place within the hair follicle,where they are useless for coloring hair.The new findings won’t lead to a scientific alternative to hair dyesany ti...

Plant hemoglobins: Oxygen handlers critical for nitrogen fixation

Hemoglobins, key components of our blood, are ancient proteins with well-known roles in oxygen transport and respiration in animals. Hemoglobins are also present in plants and bacteria, but until now the physiological role of plant hemoglobins has b...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

Few things about growing older are asinevitable and obvious as “going gray,?yet scien...he wrong place within the hair follicle,where they are useless for coloring hair.The new findings won’t lead to a scientific alternative to hair dyesany ti...

Scientists rid stem cell culture of key animal cells

...fornia study showing that existing stem cell lines are already contaminated with an animal molecule. The ... from mouse embryos. Feeder cells, or fibroblasts, are connective tissue cells that form the matrix upon which stem cells grow. The mouse feeder cells wer...

Essential mangrove forest threatened by cryptic ecological degradation

... forests thriving at the edge of land and sea that are ecologically and socio-economically important for local people in tropical countries on all continents. Using biology, geography, hydrology, socio-economic interviews, and 18th-century history, an international team led by Dr. Farid Dahdouh-Guebas ha...

Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.

Few things about growing older are asinevitable and obvious as “going gray,?yet scien...he wrong place within the hair follicle,where they are useless for coloring hair.The new findings won’t lead to a scientific alternative to hair dyesany ti...

Experiments provide proof of how traveling in groups protects insects

Few events involving animals are more dramatic than when they band together and head out on the march cross-country. Among examples are the many thousands of wildebeests and other hoofed mammals that form herds and migrate across the Af...

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

...akes them do different things involves which genes are turned on," notes Bradley Bernstein, a pathologist...urprising exception in the way some critical genes are activated by the protein packaging. These proteins act like spools for the long strings of DNA that ...

First 'atlas' of key brain genes could speed research on cancer, neurological diseases

...es?called “transcription factors.?When these genes are altered, thegenes they control can go awry, causin... major brain areasthat shows what regulatory genes are expressed in those specificlocations,?said Quifu Ma, PhD, of Dana-Farber’s Cancer BiologyDepartment....

New research questions basic tenet of neuron function

...l signals called neurotransmitters. Within neurons are tiny organelles called synaptic vesicles that sequ...gests that two distinct types of synaptic vesicles are responsible for the two different modes of neurotransmitter release ?one type of vesicle for spontan...

Vital step in cellular migration described by UCSD medical researchers

... molecular processes at the front end and back end are different, leading only to forward movement. One o... cell. The scientists noted that alpha4 integrins are widely expressed in neural crest cells, immune system leukocytes (such as T cells), striated and smo...

U-M scientists find genes that control growth of common skin cancer

...m whichthey may arise.If the results of this study are applicable to human BCC, the discoveryof residual tumor cells and tumor recurrence may be particularlyimportant given the current efforts to develop Hh pathway inhibitors asa means of combating human BCCs, as well as other cancers. In contrastto othe...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

As you read this, cells in your eye are transmitting information to your brain, while cell...e, which is one of the reasons the journal editors are so excited about this study," he said. The new technology really paid off in terms of results, he a...

Experiments provide proof of how traveling in groups protects insects

Few events involving animals are more dramatic than when they band together and head out on the march cross-country. Among examples are the many thousands of wildebeests and other hoofed mammals that form herds and migrate across the Af...

New Study from Affymetrix Laboratories Points to Changing View of How Genome Works

...they found that thousands of regions of the genome are transcribed into overlapping RNA sequences and those sequences are separated by regions in which RNA is transcribed more scarcely. All of the data is freely availab...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...ent of metastatic breast cancer cells in mice, and are the first to target only metastatic cells. "They'...s -- core macroketone and core macrolactam -- that are about 1,000 times more powerful at inhibiting cancer cell migration." In fact, in a mouse model, th...

Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine

... that is more effective inchildren than those that are currently available,?Kriwacki said.Elaine Tuomanen...oniae do not work in young children. Adultvaccines are composed of pieces of carbohydrates naturally appearing onthe surface of these bacteria. When used i...

Critical role in programmed cell death identified

...eeps the body up and running. Miscues and failures are instrumental in cancer, autoimmune disorders or ne...netics, we could rigorously show that mitochondria are part of it. It unifies two different hypothesis and makes worms a great model to analyze how cell de...

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