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Tag: "are" at biology news

Bound for destruction: Ubiquitination protects against improper Notch signaling

...receptors that have not been activated by a ligand are protected fromdigestion by that protease. Now, in a report published in the December29 issue of Current Biology, Shigeo Hayashi (Group Director, Laboratoryfor Morphogenetic Signaling) and colleagues at the RIKEN Center forDevelopmental Biology (Kobe,...

HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs

...ers emphasize that the drugs' therapeutic benefits are still greater than the risk of heart problems link...ccordingly. Worldwide, tens of thousands of people are taking protease inhibitors, and the numbers who experience these unexpected side effects are very lo...

Combination therapy boosts effectiveness of telomere-directed cancer cell death

...case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivide indefinitely) aspect of cancer cells. Yet, something in the cellseems to block their function, preventing them to inhibit completelythe telomerase. What to do then? Scrap the project? Look for something...

Inflammatory molecules released by pollen trigger allergies

...puts some of the blame on bioactive molecules that are released from pollen. These molecules bind to immu...npolluted areas, possibly explaining why allergies are more prevalent in places with high levels of car exhaust emissions. Traidl-Hoffmann and colleagues ...

GATA: a graphic alignment tool for comparative sequence analysis

...case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivide indefinitely) aspect of cancer cells. Yet, something in the cellseems to block their function, preventing them to inhibit completelythe telomerase. What to do then? Scrap the project? Look for something...

Whole genome fine map of rice completed

... maps of two strains of rice, Indica and Japonica, are better than the draft sequence published in 2002. ...ween 30,000 to 40,000. Among them, only 2-3% genes are unique to any one of the two strains. Even though the genetic difference between the two strains is...

Research on Worms Yields Clues on Aging

...top aging. While its still nowhere to be found, we are makingprogress; in worms. Researchers found that a...ous system influences aging processes. Thefindings are reported in the January 14 issue of the journal Science. Theanti-aging effect was revealed in a ran...

Imaging Lymph Nodes with Nanoparticles

...thods have problems; someare very invasive, others are very time consuming, and none arecompletely reliab...ain a centralsuperparamagnetic iron oxide core and are covered by dextran, impartinglong circulation times and biocompatibility. When injectedintravenously...

“Nano-scissors?laser shows precise surgical capability

... its ability to cut organelles(parts of cells—they are what organs are to organisms) precisely,without damaging surrounding tissue. Usually, conventional lasers usedin sur...

U-M scientist to talk about tissue engineering at AAAS

...ions of current therapies, too." These approaches are not yet being tested in humans, but Krebsbach said some small clinical trials are under consideration. If the combination therapy approach works, Krebsbach said the next step would ...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

...full post. Onlyabout 1% of newly developed drugs are for tropical diseases, such asAfrican sleeping sickness and dengue fever. While patent incentiveshave driven commercial pharmaceutical companies to make Western healthcare the envy of the world, the commercial model only works ifcompanies can sell en...

Genome-wide mouse study yields link to human leukemia

...essor genes lose that ability ?as they can if they are silenced through methylation or some other process...verse the effects of methylation," says Plass. "We are just beginning to figure out how it best works in humans, but simply knowing that we have a new targ...

Breakthrough Microarray-based Technology for the Study of Cancer

...anges in the number of gene copiespresent in cells are important events in the genesis and progression ofcancer," said Michael Bittner of the Translational Genomics ResearchInstitute. "Agilent has now taken array-CGH experiments into a newrealm of resolution, sensitivity, and reproducibility that allowsr...

The transparent organism: EMBLEM and Carl Zeiss give labs a unique look at life

...post-processing step, one or more stacks of images are assembled into a high-resolution film. Another advantage of SPIM is that the specimen is kept alive in a liquid-filled chamber, allowing scientists to track developmental processes like the formation of eyes and the brain in embryonic fish or other ...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...root cause. Other genes affected by ironstarvation are known to be vital in generating energy, copying th...f threeproteins in humans. When the human proteins are substituted in place ofCth2 in yeast, they actually assume its function in yeast cells, saidThiele."...

Learning to fight an adversary that won't stay down

...chniques have shown just how adept these pathogens are at adapting to anything we can throw at them. Inno...e environment. "What has been found is that there are more antibiotic resistance genes around than we ever realized," says Dr. Davies. "There are more tha...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...quences of genes for other proteins (most of which are from different species) in sequence databases. If ...anti-TB drugs. "Enzymes that synthesize mycobactin are drug targets, because if mycobactin biosynthesis is stopped, the bacterium cannot acquire the iron t...

Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6

...eomics AnalysisSoftware products."The new releases are focused primarily on importing and analyzingprotei...P Bioinformatics at IOS."Despite our new focus, we are still enhancing our products for geneexpression data analysis. We've added additional data import sc...

Novel Enzyme Shows Potential As An Anti-HIV Target

...transcription requires that new, unacetylated Tats are produced or existing Tats are deacetylated. Thus, efficient viral replication depends on adequate Tat supplies. And since HIV gene...

Scientists seek answers on what activates deadly anthrax spores

...aptist Medical Center and three other institutions are setting out to find what activates the spores in a...thrax is clear, as spore germination and outgrowth are fundamental to proliferation." Claiborne, co-director of Wake Forest's Center for Structural Biolog...

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