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Tag: "are" at biology news

Source of molecular triggers in cutaneous T cell lymphoma identified

...L develops from a small subset of lymphocytes that are pre-programmed to respond to self-antigens exposed...ss of apoptosis, cryptic -- or masked -- antigens, are uncovered. Those newly available antigens are presented by LC directly to CTCL receptors, stimulatin...

University of Manchester makes made-to-measure skin and bones a reality using inkjet printers

...he face using CT scans, but with thistechnology we are able to build a fragment which will fit exactly. W...reate bone grafts."Using conventional methods, you are only able to grow tissues whichare a few millimetres thick, which is fine for growing artificial ski...

Protein discovery could unlock the secret to better TB treatment

...king TB bacteria in the body. Once the TB bacteria are active again, the disease becomes treatable using ...ht per cent of the bacteria causing TB in patients are resistant to one or more drugs and one per cent show multidrug resistance. Left untreated, a person ...

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

...ut under normal conditions humans andother mammals are capable of removing UV-induced DNA damage by a DNArepair mechanism called nucleotide excision repair. Insufficient repairof UV-induced DNA damage, which for example may occur after excessiveunprotected sunbathing, can lead to cellular death ?recogniz...

W.M. Keck Foundation funds study of friendly microbes

...utational and physical sciences," Gordon says. "We are dedicated to integrating concepts and technologies...been hampered because the majority of gut bacteria are difficult or impossible to grow and study outside of the intestine. With the support provided by the...

Yellowstone microbes fueled by hydrogen, according to U. of Colorado study

...obiallife form could be using that," he said.There are many examples of bacteria living in extreme enviro...nder howmany different kinds of microbes out there are metabolizing hydrogen inextreme environments."Instead of relying on traditional techniques of microb...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

..., cells make a double dose of the IGF2 protein and are said to have "loss of imprinting" of IGF2. Althou...Princeton, have a double dose of IGF2 because they are missing another gene, H19, whose sequence overlaps the region that usually shuts off one copy of IGF...

Columbia research lifts major hurdle to gene therapy for cancer

...called PEA-3 and AP-1 that, the researchers found, are usually abundantinside cancer cells. Both of the molecules flip a switch (called PEG)that turns on the production of a cancer-inhibiting protein uniquely intumor cells.The researchers say the PEG switch can be exploited to produce genetherapies that ...

Dysentery uses 'sword and shield' to cause infection

...ime, the LPS chains on the surface of the bacteria are shortened. This allows the needles to inject prote... greatly expands our understanding of how bacteria are sometimes able to evolve although it is unlikely to result in new treatments or vaccines for dysente...

Novel technology detects human DNA mutations

...rogate both bases in the pair to determine if they are homozygous (i.e., both are mutant or normal) or heterozygous (i.e., one is mutant, one is normal) ?the most critical step in co...

Topical treatment shown to inhibit HIV and herpes simplex virus infection

...epidemic, an estimated 40 million people worldwide are living with HIV, and women account for nearly half...nai and the senior investigator on this study. "We are currently conducting a 14-day study to assess whether or not there is an inflammatory response after...

Priming embryonic stem cells to fulfill their promise

... available online on Jan. 21. Embryonicstem cells are considered the blank-slate, raw material needed to...s complex and far from fullyunderstood. Scientists are focusing on four types of external inputsknown to be involved in triggering the differentiation of s...

Growth in the sea comes down to a struggle for iron

...m of scientists from UMaine and other universities are studying the fate of iron in marine waters. Their ...ience Foundation and the U.S. Department of Energy are providing financial support. Field work got underway in July, 2004, when Wells served as chief scie...

New, automated tool successfully classifies and relates proteins in unprecedented way

...t curators," said Murphy.Murphy and his colleagues are currently amassing more protein imagedata using CD...o that they can refine their approach further.They are also working on ways to "train" a general system that willwork for different cell types....

New binding target for oncogenic viral protein

... differentiation, and cell death. "These proteins are also some of the most broadly acting cellular onco... cellular pathways that regulate cell division and are disrupted in cancer. Understanding the mechanisms through which these viruses interact with the cell...

Lack of enzyme turns fat cells into fat burners

...ogy. "We found that the adipose in the mutant mice are nowoxidizing fat, hydrolyzing (breaking down using water) fat, and passingit on to the heart and muscle because there is an increase in oxidationof fat in those organs. It also starts oxidizing glucose. In otherwords, the adipose tissue is becoming a...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

...ids. "The challenge is to figure out which factors are a primary cause of diabetes and which are a consequence, said Dr. Patti. "In our study, we needed to find out what was happening in these mice...

Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs

Physicians at Emory University School ofMedicine are conducting a clinical trial using stem cells gener...roved circulation evenduring exercise. Some people are not able to repair their own vessels,however, and physicians don't completely understand the reasons...

Fox Chase Cancer Center scientists identify immune-system mutation

...1997. Known as "helper deficient" or HD mice, they are proving to be useful for exploring the pathways of...o called because they arise from the thymus gland, are essential for combating intracellular viral and bacterial infections (cell-mediated immunity) and al...

Controversial drug shown to act on brain protein to cut alcohol use

...leagues in the research and coauthors on the paper are postdoctoralfellows Dao-Yao He, PhD, Nancy N.H. McGough, PhHD; Ajay Ravindranathan,PhD; Jerome Jeanblanc, PhD; Marian Logrip, BA, UCSF neurology graduatestudent; and Khanhky Phamluong, BA, research associate, all at theGallo Center.The research is su...

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