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Tag: "approved" at biology news

Researchers shed light on mechanism of action used by anti-cancer drug

...ctured by Bayer Pharmaceuticals, has recently been approved for the treatment of patients with renal cell cancer, the most common form of kidney cancer in adults. It was originally developed as an inhibitor of the oncogene, Raf, which is frequently mutated in numerous cancers, including leukemia. Oncogenes ar...

Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage

...no-associated vector (AAV). AAVs have already been approved as safe for experimental gene therapy by the U.S. Food and Drug Administration, eliminating a tremendous regulatory hurdle. If successful, this next study will provide the proof of principle needed for the team to apply for phase I human clinical tri...

How brain pacemakers erase diseased messages

...e clinical success of the devices, which have been approved by the Food and Drug Administration and can be fou...from the National Institutes of Health. The FDA approved the use of deep brain stimulation for Parkinson's disease in 1997. The electrical implants are also ...

NASA-funded robotic sub finds bottom of world's deepest sinkhole

... Jupiter’s moons. For the near term, NASA recently approved a project that will use these technologies to explore underneath the ice of West Lake Bonney in Antarctica’s Taylor Valley. The DEPTHX vehicle, 2.5 meters in diameter, included 56 sonars that the Carnegie Mellon team used to determine the locatio...

An 'elegant' idea proves its worth 25 years later

...of the treatment, the drug combination was finally approved by the U.S. Food and Drug Administration only in 2005. Brusilow, Hamosh, and colleagues at Stanford University, University of Minnesota, Thomas Jefferson University and the Medical College of Wisconsin looked back at 299 urea cycle disorder patie...

Smallpox outbreak: How long would it take for vaccines to protect people? Would it work?

...se its use in this study is different than the FDA approved current recommended use of this licensed vaccine. The Dryvax® vaccine is made from a live virus called vaccinia. The only people who presently receive this vaccine are people who work with viruses associated the risk of similar "pox" diseases; t...

Study shows continued success for new HPV vaccine against virus responsible for cervical cancer

...'s why it is given to adolescents. Gardasil was approved by the U.S. Food and Drug Administration last year for use in females 9 to 26 years of age. While controversy has been raised about giving pre-adolescent girls a vaccine for a sexually transmitted disease, Dr. Ault argues, "young women, young girls ...

100 percent of pregnant women have at least one kind of pesticide in their placenta

... pregnant women were used in this study, which was approved by the Ethical Commission of San Cecilio University Hospital. Mothers were informed of the study’s goals before giving their express consent. Thanks to gynaecologists, the nurses and the midwives who participated in the study, biological samples w...

Researchers wake up viruses inside tumors to image and then destroy cancers

...upon Velcade, a targeted chemotherapy drug already approved for use in multiple myeloma. "We were both surprised and lucky," he says. "Velcade is a proteasome inhibitor, but it also induces the lytic cycle thereby activating the TK in the Epstein-Barr virus. Once the TK is activated, we can image the tumors....

Cure for cancer one step closer

...rs who are part of an ethically and scientifically approved research project with tissue, matching blood samples and full clinical data, valuable funds will be saved, which can then be applied to further their research. "There is compelling evidence that new methods for screening, diagnosis and evaluation ...

Scientists genetically engineer tomatoes with enhanced folate content

...e years to get a genetically-engineered food plant approved by the FDA," Hanson said. "But before that is even a question, there are many more studies to be done--including a better look at how the overall product is affected by this alteration." And there is another hurdle the researchers must clear. Boos...

Penn researchers show how nanocylinders deliver medicine better than nanospheres

... foods. Although synthetic, PEGs have already been approved as biocompatible to humans, making them ideal carriers, note the researchers. While these findings could impact the way lung cancer is treated, this discovery of how to more effectively deliver drugs to the body could also improve the treatment of...

Bypassing eggs, flu vaccine grown in insect cells shows promise

...gh doses. The experimental vaccine differs from approved vaccines in another way as well. The experimental vaccine focuses on a portion of the flu virus known as the hemagglutinin, which the virus uses to attach to blood cells. Unlike conventional vaccines, FluBlOk does not also include neuraminidase, an e...

Misclassified for centuries, medicinal leeches found to be 3 distinct species

...essive diversity." While Hirudo medicinalis was approved by the U.S. Food and Drug Administration (FDA) in ...econstructive surgery, Hirudo verbana has not been approved by the FDA and has no special conservation status. "This study is a great example of why the fiel...

Africa's first large-scale HIV vaccine study launches

...ial will last about four years. The trial has been approved by the South African Medicines Control Council and the South African Department of Agriculture, and has been reviewed by the US Food and Drug Administration. Approval has also been given or is pending by institutional ethics and bio-safety committees...

Rapid oral HIV test shows great promise according to MUHC-led research

...ting. Although the oral OraQuick test has been approved by the US Food and Drug Administration, some previous studies had indicated that it was not sufficiently precise. As a result, the Centre for Disease Control (CDC) called for more definitive studies leading to this study in rural India. "Based on...

Scientists sequence genome of parasite responsible for common sexually transmitted infection

...-its energy source and the target of the two drugs approved to treat trichomoniasis--and identified possible ways the parasite may become resistant to these medications. Understanding how T. vaginalis causes infection and developing methods to prevent it could also help curb the transmission of other STIs oft...

Study to explore using magnets to correct 'sunken chest'

...od and Drug Administration, which has reviewed and approved the 3MP device. The internal magnet is laser-welded in a titanium case, assuring its safety. The magnets have been found to have no effect on the heart or other body parts, and studies have demonstrated that long-term exposure to magnetic fields is n...

UCSF brain tumor vaccine trial shows promising results

...valuate efficacy.?Brem is a developer of the first approved local therapy for glioma. The UCSF clinical trial is a phase1/2 study designed to establish the feasibility, safety and preliminary efficacy of vaccination in patients with recurrent, high-grade glioma. The trial involves two groups of six patient...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

... can be used to guide the use and testing of other approved and experimental drugs," Gray said. "This is impo...ells to lapatinib, a cancer drug that was recently approved for use in metastatic breast cancer under the name Tykerb. The study, a collaboration with Glaxo...

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