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Tag: "appropriate" at biology news

Scientists solve 30-year-old mystery of mutant mouse's kidney woes

...h diseases would be to redirect the protein to its appropriate location." Results from Chen and his colleagues are published online in the Proceedings of the National Academy of Sciences. Ultrasonic scans reveal fetal hydronephrosis, or enlargement of the kidney, in approximately 1 in every 100 human fetuses...

A simple feedback resistor switch keeps latent HIV from awakening

...ion of the protein by cellular machinery. When the appropriate conversion and destruction rates were fed into their model, activated Tat appeared briefly after a stray burst of transcription but quickly disappeared without breaking viral latency. This prediction of the model was then precisely replicated in cell...

Gene chip technology shows potential for identifying life-threatening blood infection

...patients so they could be treated earlier with the appropriate antibiotic," Cobb says. The researchers used microarrays, also called gene chips, to analyze patterns of gene expression in the mice. The same technology is already used by doctors to diagnose breast cancer and predict a patient's response to vari...

Research links 'ecstasy' to survival of key movement-related cells in brain

...son's. "While MDMA itself isn't likely to be an appropriate therapy for neurodegenerative diseases, it may provide insights for developing new drugs that have similar properties. "It's exciting to learn that an abused drug may have potential use for developing new therapeutics," he added. "It really makes ...

MIT designs portable 'lab on a chip'

...d a heart attack or a stroke, they could start the appropriate treatment right away. Labs on a chip can also be used in traditional chemistry or biology labs to speed up processes such as DNA testing or screening for the presence of certain antigens. Only tiny amounts of reactants would be needed, and experim...

Holiday gluttony can spell disaster for undiagnosed diabetics

... walks to see holiday displays. If you are an appropriate weight for your age, maintain your weight. In certain ethnicities, such as Asians, even modest weight gain can set the stage for developing diabetes. Long-term tips include: If you are overweight, try to lose 5 percent to 7 percent of your bo...

Beyond the book: Software automates access to brain atlases

...she superimposes her research images on top of the appropriate atlas page and then saves the superimposition as a copy. So far, the only users have been researchers in Swanson's lab, says Burns, but he expects once scientists in the field learn about the work, download the software and try it out, the advantag...

Engineer ramps up protein production, develops versatile viral spheres

...ry specific protein designed to stimulate only the appropriate immune-system cells. A vaccine with these well-targeted capsids would be more likely than a traditional vaccine to elicit a strong and specific response. The capsid method is akin to advertising a product directly to the people who are most likely to...

Molecular 'signature' protects cells from viruses

...ed. If a particular protein is to be produced, the appropriate command is 'copied' in the cell nucleus. The copy consists of a DNA-like substance, the RNA. Via pores in the cell nucleus it reaches the cell plasma. The individual parts of the desired protein are put together there on a kind of assembly line. In t...

Key to lung cancer chemo resistance revealed

...ith a larger set of samples and then to screen for appropriate drugs. Funding for the study was provided by the National Cancer Institute Lung SPORE (Specialized Program of Research Excellence), National Heart Lung and Blood Institute, National Institute of Environmental Health Sciences Center, National Instit...

Drug can quickly mobilize an army of cells to repair injury

...ents like AMD3100. "It might be better to let the appropriate cells find their way through the circulation to the site of injury or low oxygen," he says. "That way you enhance a normal repair mechanism instead of using the brute force of injecting a mixture of many cell types from bone marrow into the affected ...

Scientists design simple dipstick test for cocaine, other drugs

...wicking, conjugation, membrane and absorption. The appropriate aptamer-linked nanoparticle aggregates are placed on the conjugation pad, streptavidin is applied as a thin line to the membrane pad, and the device is then dried. When dipped into a solution, or swabbed with a sample, the wicking pad carries the f...

Researchers develop technologies to devour food pathogens

...remaining is optimizing the system to dispense the appropriate amount of chlorine dioxide, Morgan said. Enough of the gas must be deployed to kill the pathogens, but too much can cause a decrease of quality in the product, such as browning of leafy greens. "If the product is safe, but nobody will eat it, that'...

Gene-bender proteins may sway to DNA

...lays in guiding the correct bending protein to the appropriate site on the DNA. Ansari said the research adds to the basic understanding of how proteins recognize a specific binding site. "Gaining better insights into protein-DNA interactions that control all aspects of gene regulation may prove useful for ...

Proteins necessary for brain development found to be critical for long-term memory

... trick" to keep the proteins from binding with the appropriate TrkB receptors. For the experiment, the scientists used wild-caught Aplysia, a marine snail frequently studied in learning and memory because of its large brain cells. The Aplysia received a series of five tail shocks, spaced 15 minutes apart. The ...

Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration

... to repairing damaged retina by transplantation of appropriate cells can be successful." Swaroop sees several next steps in his quest to find treatments for retinal and macular degeneration. His research team will continue to study the properties of photoreceptor cells and mouse models to learn more about th...

Increase in drug development for killer diseases is not enough

...that correct market incentives and, in particular, appropriate intellectual property management are lacking. Eiss states that there is a "need to develop and promote forms of intellectual property management and technology transfer practice that help ensure access for the poor through the strategic use of such ...

NASA satellite data helps assess the health of Florida's coral reef

...andsat.pl to determine which reef areas were most appropriate for sampling. Funded by NASA and created at the University of South Florida, the global map divides Florida's coral reef into about 70 different reef zones. After the findings from each sampling site are analyzed over the next few months, scientist...

'Super' enzyme may lead way to better tumor vaccines

... and active, the more likely you are to expand the appropriate T-helper repertoire and ultimately the desirable cytotoxic (cell killing) T-lymphocytes." "The dendritic cells are the master switch in the immune system. They decide whether there will be a robust immune response or a tempered immune response to p...

New approach to BSE successful in lab

...ting these from being ‘read? The production of the appropriate protein is thus shut down. This effect is known as RNA interference; its discovery was rewarded with this year’s Nobel Prize for Medicine. “We modified the brain cells of mice in such a way that they were able to produce siRNAs in place of the ‘healt...

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