SuperLigands - a database of ligand structures derived from the Protein Data Bank
...stics of the disease, so they will probably not be appropriate for direct use in treating patients. In addition, researchers must develop methods to efficiently direct the differentiation of embryonic stem cells to specific stable cell types. Scientists must also find a way to remove the remaining animal compone...A new way to share models of biological systems
...e components of models, and helps them to retrieve appropriate models, which they can then visualize and build upon using any SBML-compatible software. "Ultimately," says Le Novère, "we hope that publishers will encourage any author who plans to publish a new model to submit it to the BioModels database; this w...Where bacteria get their genes
...es of Streptococcus and can therefore prescribe an appropriate antibiotic. If you couldn't classify bacteria because they have genes from all over, doctors wouldn't be able to do this." The research report is published in the current issue of PLoS Biology, available on www.plosbiology.org. Ochman's coauthors ar...Analysis Of Human Genome To Predict The Development Of Illnesses
...of the sickness using the gathered data. Using the appropriate analyses, it enables the measurement of the efficiency of and patient response to the different treatments administered, thus enabling the identification of new, more effective therapeutic targets. This new tool is available on Internet, thus enabli...Active Vaccine Prevents Mice From Developing Prion Disease
...he vaccine for deer and cattle. After choosing the appropriate bacteria for each vaccine, they must genetically modify it to carry the prion protein. "These technical issues are not major hurdles," says Dr. Wisniewski. "Developing a marketable vaccine for livestock is something that is very achievable." The aut...Asymptomatic HIV babies could use earlier treatment
...ssociation, suggests that early treatment might be appropriate for at least some apparently healthy infected infa...ard to figure out if this treatment is going to be appropriate for everyone.?/p> Clinical trials are needed to determine if every infected newborn should be tr...Survey reveals women and doctors aren't talking about HPV
... regular screening with the available technologies appropriate to each age group," said Wayne Shields, president & CEO, ARHP. "One of the keys to making prevention possible is broader education of both women and providers, focusing on informed, shared decision-making." Survey Methodology A survey, fielded ...Stem cell treatment improves mobility after spinal cord injury
...o full-grown oligodendrocyte cells and migrated to appropriate neuronal sites within the spinal cord. In the rats treated seven days after the injury, myelin tissue formed as the oligodendrocyte cells wrapped around damaged neurons in the spinal cord. Within two months, these rats began to show significant impr...Random gene expression may drive HIV into hiding
...ferent qualitative behaviors," said Arkin. If the appropriate modifications take place, then the HIV genome is transcribed and the positive feedback loop kicks in. If these Tat modifications don't happen, then HIV ceases to be expressed, and the cell can then possibly enter a latent state. The significance of ...Any exposure to tobacco smoke during pregnancy is risky
... like certain pharmaceutical warnings, it would be appropriate to caution women to quit smoking if they are pregnant or likely to become pregnant. It is equally imperative that workplace protection be offered to reduce passive exposure." ...Where Bacteria Get Their Genes
...es of Streptococcus and can therefore prescribe an appropriate antibiotic. If you couldn't classify bacteria because they have genes from all over, doctors wouldn't be able to do this." The research report is published in the current issue of PLoS Biology, available on www.plosbiology.org. Ochman's coauthors ar...Speak up: Louder neurons form more connections
...d to produce a protein that glowed green under the appropriate light. Hua looked for green neurons in her immobilized fish to see how their branches fared compared with neighboring neurons that fired normally. The green neurons didn’t compete well. Although the poorly-firing green neurons still formed extensiv...Confirmation of human protein interaction data by human expression data
...d to produce a protein that glowed green under the appropriate light. Hua looked for green neurons in her immobilized fish to see how their branches fared compared with neighboring neurons that fired normally. The green neurons didn’t compete well. Although the poorly-firing green neurons still formed extensiv...New Vaccine To Be Used For First Time In Polio Outbreak Response
...rol the outbreak and to intensify the planning for appropriate supplementary immunization activities. Four cases of polio were confirmed on 20 April in just one governorate in the south-western part of the country, on the Red Sea coast. The latest 18 cases occurred across five governorates throughout Yemen, inc......ar reward and signaling to the muscles to take the appropriate action to receive the reward. Computer models of how a bee assimilates and responds to information about a reward can be then applied to studies of how humans make decisions about rewards. And predictions from computer modeling of the bee brain can ...Environmental chemical cocktail may sabotage sperm
... compounds have acted on the cell, that prompts an appropriate response. In the case of sperm, increased cAMP production appeared to stimulate premature sperm capacitation. "The sperm were still alive and their ability to move was unaffected, but the spontaneous acrosome reaction meant that they were unable to f...Decisions, decisions: Male or female?
...from other cells within embryos as to which is the appropriate sex. The Johns Hopkins researchers have found that this advice is delivered by a sequence of chemical reactions called the "JAK/STAT" pathway. ("JAK/STAT" is an acronym for "Janus kinase/signal transducer and activator transcription.") "Though we al...Researchers seek to discover what really happens when a virus enters the body
...rofiles to better predict their behavior and start appropriate treatment. Ultimately, their work should contribute to what starts an immune response. And as NIH's Matzinger says, knowing what initiates an immune response will affect and, researchers hope, improve medical treatment. Bell is an associate membe...OHSU research shows vitamin C counteracts some negative impacts of smoking on unborn babies
...re research is needed in regard to determining the appropriate vitamin C dosage for humans. Finally, studies need to be conducted to demonstrate that giving pregnant women higher levels of vitamin C will not itself cause development problems. The ONPRC is a registered research institution, inspected regularly b......ation has stated that the DNA itself codes for the appropriate pairings for replication. In other words, if a guanine base is on the original strand of DNA then its partner, a cytosine base, will pair to it on the replicated strand. In a study published in this week's issue of Science, researchers from Mount Si...