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Tag: "approaches" at biology news

W.M. Keck Foundation funds study of friendly microbes

...lp fill this gap by funding a study to develop new approaches for isolating, sequencing and analyzing the genomes of "friendly" bacteria that inhabit the intestine and identifying the natural metabolic products that they synthesize in their native gut habitats. The W.M. Keck Foundation, established in 1954 by ...

New, automated tool successfully classifies and relates proteins in unprecedented way

... found. Of course, theother drawback of term-based approaches is that they have to beassigned manually by database curators, and this is often notconsistent between different curators," said Murphy.Murphy and his colleagues are currently amassing more protein imagedata using CD Tagging so that they can refine t...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...e Medicine paper, notingthat none of the suggested approaches guarantees the completeelimination of Neu5Gc from existing cultures. "Therefore, it would seembest to start over again with newly derived human embryonic stem cellsthat have never been exposed to any animal products, and ideally, onlyever exposed to ...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...ine, and will help us start strategizing about new approaches to vaccine development." The studies, performed in the Children's Hospital Boston Laboratory of Molecular Medicine, used the closely related simian immunodeficiency virus (SIV) as a stand-in for HIV. By aiming an X-ray beam through a crystallized fo...

Inflammatory molecules released by pollen trigger allergies

...cules and how they work may eventually lead to new approaches to treating allergies. ...

U-M scientist to talk about tissue engineering at AAAS

...e complications of current therapies, too." These approaches are not yet being tested in humans, but Krebsbach said some small clinical trials are under consideration. If the combination therapy approach works, Krebsbach said the next step would be working with engineers to develop anatomically correct scaffo...

Learning to fight an adversary that won't stay down

... put hundreds of millions of dollars into 'modern' approaches to antibiotic discovery over the past six or seven years and this has failed miserably." The scientist, whose work is supported by Science and Engineering Research Canada (NSERC), has organized a symposium on the evolutionary genetics of antibiotic ...

Female sex hormones play a vital role in defense against sexually transmitted diseases

...at we need to promote more gender-specific medical approaches in future," she said. "We have to increase awareness in both the medical community as well as the public regarding sexually transmitted diseases and women." Extending these findings into clinical studies is the next step. McMaster researchers are cu...

Gene variations explain drug dose required to control seizures

...the higher dose." Before any such pharmacogenetic approaches can be put into practice, they must be explicitly evaluated for clinical utility in improving patient outcomes, Goldstein said. The new findings provide a direction for a dosing scheme that could be tested in the clinic to assess whether pharmacogen...

Enzyme shown to help protect genomic stability

...lencing could provide important guideposts for new approaches to retarding aging or treating cancer. Now, an investigation led by researchers at The Wistar Institute has shown that an enzyme known as Ubp10 plays a vital role in protecting the telomeric regions of the genome from potential destabilizing molecul...

Alcohol's effects on gene expression in the central nervous system

...ments in microarray technologies and bioinformatic approaches to better understand the complex neurobiological mechanisms underlying alcohol addiction. "Future research will need to determine changes in gene expression in very discrete neuronal pathways that may be involved in mediating the effects of alcohol t...

Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease

...Such basic understanding, they said, could lead to approaches to preventing plaque formation. The researchers led by Boris Akhremitchev are using the infinitesimal tip of a customized atomic force microscope (AFM) to capture, isolate and study single molecules, called monomers, that are the building blocks of ...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

... genetic modifiers, and into potential therapeutic approaches that affect the signaling between the two cell layers. ...

Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications

...ed. Prof. Ying’s group at IBN has developed novel approaches to immobilize these catalysts on nanoporous materials synthesized by its wet-chemical technique. This renders the catalysts in a solid form, enabling them to be easily recovered and reused through simple filtering or centrifuging processes. This allo...

Boosting HIV screening can increase survival and is cost effective

...ul of easily identifiable risk groups, yet current approaches to HIV testing are still focused on these sub-populations. The result is that 280,000 Americans with HIV remain unaware of their infection. Efforts to promote and finance routine, population-based HIV screening should be pursued aggressively." Dougl...

Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals

...ody or don't provide high-resolution images. Other approaches using MRI are not practical for a wide range of applications. Ahrens and his colleagues constructed a gene carrier, or vector, that contained a gene for the MRI reporter. They used a widely studied vector called a replication-defective adenovirus th...

Measuring the impact of post-genomics on Mediterranean populations

... opportunities to improve scientific knowledge and approaches to improving human health and welfare. The workshop, organised by the Pasteur Institute in Tunisia earlier this month, set out to explore how discoveries in this field can help the Mediterranean region. Once research priorities were identified, dele...

VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain

...alcohol and may eventually lead to new therapeutic approaches for alcoholism," said Michael Miles, M.D., Ph.D., a professor in pharmacology, toxicology and neurology, who also has an appointment in VCU Life Sciences' Center for the Study of Biological Complexity. Gene expression refers to how much a given gene...

Sequencing of marine bacterium will help study of cell communication

...ractions, we must begin to use comparative genomic approaches with closely related pathogenic and beneficial microbial species." Marie Faini O'Brien of Frederick, Maryland, earned her master's degree in biology in April 2003. ...

UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

...us blocks stem cell function, as well as stem cell approaches to combating HIV disease. One potential therapeuti... isolation, microarrays and shape encoded particle approaches for gene expression analysis, proteomics using advanced mass spectroscopy, large-scale computational...

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(Date:10/15/2014)... 44th Rosenstiel Award for Distinguished Work in Biomedical Science ... mechanisms of genomic instability and its implications for the ... alumnus to win the Rosenstiel Award; the first, Rod ... is the Charles A. Janeway Professor of Pediatrics and ... investigator at the Howard Hughes Medical Institute at Boston ...
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Breaking Biology News(10 mins):New book about life as seen from physics 2Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2House fly genome reveals expanded immune system 2
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