Jefferson scientists find rabies-based vaccine could be effective against HIV
...the safety and effectiveness of the rabies vaccine approach against HIV and related diseases. Four macaques were immunized with both vaccines, while two animals received only a weakened rabies virus. After they gave the animals an initial vaccination, they then tried two different immune system boosts, but...Gut research yields new anti-cancer approach
...ggest that general toxicity does not rule out this approach as once feared. With new drug delivery technologies that help drugs target only cancer cells, we are very excited about the potential of this line of work." ...Beyond the DNA: Chemical signatures reveal genetic switches in the genome
..., the method is widely applicable and its unbiased approach is likely to yield new information on gene express... how it is altered in disease. "The beauty of this approach is that it utilizes a chemical signature present on histones but not DNA. Existing methods to predic...Glucose triggers brain cell death in rats after hypoglycemic coma
...ean that clinicians should take an overly cautious approach to hypoglycemic coma." In his own current research, Swanson is investigating the possible roles of glucose and NADPH oxidase as agents of oxidative stress in a rodent model of ischemic stroke. "So far, the results are very promising," he says. ...Study finds antibiotic resistance in poultry even when antibiotics were not used
...us the evidence from the Baytril ban suggests that approach won't help. "They banned Baytril in 2005, and if you look at Baytril resistance in campylobacter now it's essentially unchanged," Lee said. In previous studies, Lee has tried to recreate experimentally conditions that should lead to the swappi...... Kimoon Kim have now developed a very simple novel approach for the direct production of polymeric nanocapsules. As described in the journal Angewandte Chemie, this method is generally applicable to any monomers as long as they have a flat core and multiple polymerizable groups at the periphery. Additionally,...Major gene study uncovers secrets of leukemia
...viously unattainable. The St. Jude group used this approach to analyze leukemia samples from 242 pediatric pat...y was surprising, it is important to note that the approach used provides a lower limit of the true frequency of these mutations, since not every gene in this p...Veterinary scientists explore poultry virus as cancer killer
...ation and hypothesis development for an innovative approach to treating prostate cancer. Subbiah and his co-investigator, Dr. Siba K. Samal, associate dean, University of Maryland campus, received a $113,250 grant for their ongoing work using a genetically modified version of NDV to treat prostate cancer ...Woven scaffolds could improve cartilage repair
...way would likely be hips and shoulders, though the approach should work for cartilage damage in any joint." ...ive, the researchers said. The only bioengineering approach to such joint repair involves removing cartilage cells from patients and then "growing" them in a la...Metacognition: Faced with a test, rats can check their knowledge first
...ard. In the new work, researchers utilized this approach to study the knowledge rats had of the information they possessed. During the "study phase" of the experiments, rats were presented with a brief noise of either short duration (between 2 and 3.6 seconds in length) or long duration (between 4.4 and 8 ...Tracking sperm whales and jumbo squid
...tat," Davis noted. "In the future, this co-tagging approach should yield new insights into predator-prey interactions with other pelagic species that are large enough to carry electronic tags." Added Gilly: "Although human observers at the surface of the sea must still infer what the mysterious squid and t...NT researchers discover breakthrough in malaria treatment
...his "post treatment prophylaxis" is similar to the approach of giving travelers regular medication to protect them from infection, but can be applied opportunistically to people at high risk of infection in poor tropical communities." he added. A concern with such a policy is that the resistance will emerg...NIAID DNA vaccine for H5N1 avian influenza enters human trial
...s colleagues previously have shown the DNA vaccine approach to be effective against influenza viruses in animal models, including highly pathogenic viruses such as the H5N1 strain and the H1N1 virus that caused the deadly 1918 pandemic. The DNA vaccine used in this study is similar to other investigational va...3 proteins may play important role in nerve-cell repair
...ules, and we are very keen to find out whether the approach can be translated in preclinical animal models of stroke or spinal cord injury." ...Robotic exoskeleton replaces muscle work
...rehabilitation and physical therapy, and a similar approach could be used by other groups who do build such technology. "This could benefit stroke patients or patients with incomplete injuries of the spinal cord," said Daniel Ferris, associate professor in movement science at U-M. "For patients that can wa...Africa's first large-scale HIV vaccine study launches
...this study will guide whether this type of vaccine approach offers promise to interrupt the continued spread of HIV. Additionally, the South African study is likely to provide important new data on how the test vaccine might work in a predominantly heterosexual HIV epidemic, how well the vaccine works in w...NASA predicts nongreen plants on other planets
...l Pilcher, director of the NAI at NASA Ames. "This approach -- studying Earth life to guide our search for life on other worlds -- is the essence of astrobiology." Kiang and her colleagues calculated what the stellar light would look like at the surface of Earth-like planets whose atmospheric chemistry is ...A rarity among arachnids, whip spiders have a sociable family life
...cially interactive groups. As soon as the siblings approach sexual maturity though (about 12 to 14 months of age), they start showing aggressive, life-threatening behavior toward each other. To test if D. diadema were congregating simply to inhabit a preferred site in the cages, Rayor and Lisa Taylor, CAL......mately, we hope to offer a new polypeptide vaccine approach that induces tumor killing without causing HER-2/neu loss. Loss of HER-2/neu is a mechanism that tumors utilize to escape the immune-mediated destruction," he said. Since 2000, Manjili and his colleagues have been employing animal models of breast...