Researchers in Montréal and the US create model of key immune-system component
...d Canada have enabled us to pool our resources and apply promising new approaches like systems biology." As Dr. Stuart explains, "Phagocytes are immune system cells that internalize, kill, and digest bacteria within an intracellular compartment called the phagosome, a major battleground in the host-path...Lab-on-a-chip could speed up treatment of drug-resistant pneumonia
...ases," Lochhead said. The company also hopes to apply the technology not just to identifying known strains but also to testing the efficacy of new drugs, or of existing drugs on unknown strains. "Even if you don't know the identity of an organism, if you know which drug works, it's still useful," Lochhe...Regulating the nuclear architecture of the cell
...ar organization is controlled in the fruit fly can apply to human disorders like birth defects and cancer. The organization of structures in the cell's nucleus has profound effects on such essential functions as how and when genes are expressed. When regulation fails, genome aberrations accumulate, includi...Some butterflies travel farther, reproduce faster
...ely to survive and reproduce. "What we learn could apply to any organism that has to move to find food," he added Åland Islands are natural laboratory The study, "Population history-dependent reproductive physiology in a butterfly metapopulation," will be presented on Oct. 10 at Comparative Physiolog...Silver bullet: UGA researchers use laser, nanotechnology to rapidly detect viruses
...ollege of Veterinary Medicine. "You could actually apply it to a person walking off a plane and know if they're infected." The technique, called surface enhanced Raman spectroscopy (SERS), works by measuring the change in frequency of a near-infrared laser as it scatters off viral DNA or RNA. This chang...Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack
...ublic Health and Community Medicine. These results apply to scenarios involving even the most virulent, fatal forms of the virus. However, Longini emphasizes, failure to quickly isolate known smallpox cases and vaccinate their close contacts could thwart the containment of an epidemic. These findings e...Does natural selection drive the evolution of cancer?
...ing therapeutic resistance," Maley adds. "When you apply chemotherapy to a population of tumor cells, you'r...esistant cells that are in the tumor. And then you apply your chemotherapy. So you sucker the tumor into a vulnerable state and then you hit it with your the...Flu shot effective against drifted influenza, nasal spray vaccine less so
...t was 48 percent effective. These results may only apply to the 2004-05 flu season," said Dr. Arnold S. Monto, professor of epidemiology. "In other years the results may be different. We need a more specific understanding of which viral changes matter and which don't. There are many things about vaccine pr...World's smallest cancer detection device
...ue expertise and resources of both institutions to apply nanoscale principles to detect diseases and develop treatments for them," says Ira M. Millstein, chairman of the Einstein Board of Overseers. "We are committed to ensuring that the Einstein-Albany alliance will lead the nation in efforts to use nanot...Effective HIV control may depend on viral protein targeted by immune cells
...dy, which reflect chronic HIV infection, might not apply in situations in which vaccination generates an immune response before infection occurs. "The possibility that there may be fundamental differences between the impact of Gag and non-Gag CD8 responses on the ability to control HIV has clear relev...Ocean temperature predicts spread of marine species
...rine animals with a larval life cycle. "We can apply this rule to animals without having to go out and measure every species," O'Connor said. "Our general model gives us a powerful new way to study larval movement with knowledge about ocean temperature, which is much easier to come by. With models such...Save the whales? Sure, but how many?
...et PTLs, and showed the diverse ways in which they apply to national laws and international treaties. According to the paper's author, WCS ecologist Dr. Eric Sanderson, 'minimum viable populations' ?the goal commonly used by wildlife managers that aims to have self-sustaining populations ?should be seen ...What animals can tell us about hemorrhage, organ transplants and aging
... uncover general physiological principles that may apply to humans, and may spur future medical advances to benefit people. These scientists exude an enthusiasm for their work and maintain a wonderment of the physiological adaptations in the animal world. Science writers can meet and interview many of th...Light-sensitive photoswitches could restore sight to those with macular degeneration
... from one branch of science - nanotechnology - and apply it to another - medicine," according to Isacoff. The nanoscience breakthrough at the core of the research was developed at UC Berkeley and LBNL over the past several years by neuroscientist Richard Kramer, professor of molecular and cell biology, D...Biological motors sort molecules one by one on a chip
...l closed liquid channels. This made it possible to apply a strong electrical field locally at the Y-junction in the channels. Because of this, the electrical force could be exerted on the individual microtubules. The researchers discovered that by using this electrical force they could push the front of th...Drug dials down the energy within cells, UM researchers find
...getic pathways. Now we have some rules that we can apply to be able to modulate the mitochondria in new ways that could be therapeutic." Ultimately, the findings may have applications not only for lupus, arthritis and psoriasis, but also for other conditions, Glick believes. "There are other diseases---ce...Loosen up, DNA: Leukemia gene changes genetic packaging
...ill take what we have learned from fruit flies and apply the findings to people," said Li. "If this phenomenon occurs in people as well as flies, which is likely, it could form the basis for new treatments for people with leukemia and lymphoma." The studies conducted in fruit flies by Li, who aims to un...Plant protection from cold decoded
... negative impacts," Zhu said. "This process should apply to all plants and can help us better use crops of subtropical origin such as corn, rice, avocadoes and strawberries." Zhu said the discovery of how HOS1 acts on plants should help his overall research efforts into how plants respond to environmental...Surprise finding for stretched DNA
...onse to the stretching can be recorded. "When we apply tension to the DNA molecule, changes in the rotor bead angle reflect changes in the twist of the lower DNA segment," Bustamante said. "The overwinding observed upon stretching, implies that contrary to the held belief, the stretch-torsion coupling co......how much a product is worth. This approach doesn't apply well to many ecosystem services that are either indispensable--like air to breath--or exceedingly subtle--like global climate regulation. "Instead, we're looking for effects of ecosystems on human welfare, whether people perceive them or not--rath...