Human albumin from tobacco plants
...% of the total soluble protein of the plant, while application of the plastidial system multiplies this percentage by fourteen (to 7%), reaching an average of 0.9 milligrams of HSA per gram of fresh leaf weight. The key is the place where the gene in question is deposited. With the nuclear transformation metho...New drug could reduce tissue damage after heart attack
...sed, and the inhibition of CRP may thus find broad application in medicine." Patents, patent applications and proprietary knowledge related to this work are owned by Pentraxin Therapeutics Ltd, a UCL spin out company of which Professor Pepys is director. ...'Accelerated evolution' converts RNA enzyme to DNA enzyme in vitro
...thing new about evolution, and they have potential application as therapeutic and diagnostic agents." ......abies need very small quantities and no commercial application for adults has been found, the patent-owning company has opted not to market it arguing that it lacks profitability. Thus, an industrial version of the liquid respirator is yet to be developed ...Intelligently designed molecular evolution
...," said Keasling. "It was our contention that the application of the theory of divergent molecular evolution to promiscuous enzymes would enable us to design enzymes with greater specificity and higher activity." To test this idea, Keasling and his students worked with a type of naturally occurring hydrocarbon...Diabetes researchers pioneer islet cell xenotransplantation in primate studies
...e must find new donor sources to allow large-scale application of islet cell transplantation in humans," said Dr. Larsen. "While there is much work to be done these studies suggest that the rejection response to porcine islets can be surmounted." "The next step is to prove that these neonatal porcine islet cell......ble methods of immunization, which include topical application to the skin, pills, nasal sprays, injections, and others. Considerable advances have been made in the past decade, especially in transdermal (through the skin) and nasal immunization. "Unfortunately, because of the development costs of new immunizat...Researchers use 'trickery' to create immune response against melanoma
...to target a myriad of important human cancers. The application of nanotechnology to cancer therapy is expected to result in future therapeutic modalities that are superior to our current approach. Importantly, this is no longer a farfetched science. Nanoscale drug delivery vehicles are getting closer to clinical...Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates
...to target a myriad of important human cancers. The application of nanotechnology to cancer therapy is expected to result in future therapeutic modalities that are superior to our current approach. Importantly, this is no longer a farfetched science. Nanoscale drug delivery vehicles are getting closer to clinical...New technique puts brain-imaging research on its head
...ain injuries and concussions. "The most immediate application of our data will be in the development and validation of computer simulations of traumatic brain injury, which may ultimately reduce the need for direct experimentation." Bayly and Genin are collaborating with David Brody, MD, Ph.D., instructor in n...NIH launches comprehensive effort to explore cancer genomics
...nding of the molecular basis of cancer through the application of genome analysis technologies, especially large-scale genome sequencing. The overall effort, called The Cancer Genome Atlas (TCGA), will begin with a pilot project to determine the feasibility of a full-scale effort to systematically explore the un...OHSU discovery sheds light into how stem cells become brain cells
...erve cells has important implications for clinical application in spinal cord repair strategies." ...USC researchers track down the stem cells that create feathers
...f feathers is fascinating, it is the potential for application to human stem-cell studies that really motivates Chuong and his team. "What we are really learning about is how stem cells are assembled into organs in nature. In this way, we can take advantage of the distinct patterns of the feather as a model to ...Researchers make long DNA 'wires' for future medical and electronic devices
...velopment. Lee and Guan are working on their first application ?building the wires into sensors for detecting disease biomarkers. In the meantime, they are collaborating with researchers in the Department of Electrical and Computer Engineering at Ohio State to measure the electrical properties of the DNA wires. ......999, the numbers who changed their mind during the application and testing process rose. The acceptability rate of donors (donor release rate) also declined over the study period because of the introduction of stringent criteria aimed at improving standards of recruitment. Lead author Dr Sudipta Paul, who is no...Cancer support cells may evolve, fuel tumor growth, study shows
...e of the journal Cell.While not offering immediate application to the treatment of human cancers, the research indicates that new anti-tumor therapies may be more effective if their targets are broadened to include molecules within supporting cells of the cancer.These additional target cells are in the tumor's s......en industry and academia aimed at accelerating the application of knowledge of genomics in biomedicine and healthcare. The programme funded 21 projects covering diverse research areas. Highlights from the programme include: Nerve tissue regeneration- During spinal cord injury the nerves that transmit inform...Compound from marine bacteria shows potential as multiple myeloma therapy
...ny plans to file an investigational new drug (IND) application by the end of the year, with trials at several centers ?including Dana-Farber ?starting in early 2006. ...Cells from amniotic fluid used to tissue-engineer a new trachea
...d good healing. The FDA is now reviewing Fauza's application to conduct a clinical trial in human babies with a prenatal ultrasound diagnosis of CDH; the amniotic fluid would be collected several months before birth and a tissue-engineered patch made ready for use soon after delivery. His team is also working ...Clinical trial to test stem cell approach for children with brain injury
...tion approved Cox's Investigational New Drug (IND) application in September. The UT-Houston CPHS, the university's institutional review board for research projects, approved the project in November and will continue to monitor it. The project is funded by the Memorial Hermann Foundation, internal research fu...