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Chemists create 'Superbowl' molecule; May lead to better health

...ecule will actually enter the consumer market, but any useful application is likely to take five to ten years, the researcher estimates. Administration of the molecule for drug delivery could be by mouth or by injection, he adds. There are hurdles to overcome. The current version of the superbowl molecu...

DNA Molecules Used To Assemble Nanoparticles

... of molecules---drugs, contrast agents---to almost any cell," said Dr. James R. Baker Jr., the Ruth Dow Doan Professor of Nanotechnology and director of the Center for Biologic Nanotechnology at U-M. Nanoparticle complexes can be specifically targeted to cancer cells and are small enough to enter a dise...

Wisconsin scientists grow critical nerve cells

...ability to replicate indefinitely and develop into any of the 220 different types of cells and tissues in the body. But researchers have struggled to convert blank-slate embryonic stem cells into motor neurons, says Zhang. The goal proved elusive even in simpler vertebrates such as mice, whose embryonic...

Association of herpesvirus with lung disorder questioned

... failed to detect either the antigen or the DNA in any of the 22 samples from the two groups with some form of pulmonary hypertension, whereas the antigen was detected in the control group of Kaposi's sarcoma tissue samples. These data suggest that human herpesvirus 8 infection is not associated with Ja...

A new mechanism of regulating RNA degradation

...even more complex than we first imaginated... As any dedicated video game player knows, the first requirement for using a weapon or tool is finding it. And it is no different for cell biologists and clinicians who want to take control of gene expression in cells to create therapies to treat disease. Wh...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...even more complex than we first imaginated... As any dedicated video game player knows, the first requirement for using a weapon or tool is finding it. And it is no different for cell biologists and clinicians who want to take control of gene expression in cells to create therapies to treat disease. Wh...

Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

...ite. "It is unclear at this time whether there are any interventions that could alter DNA repair capacity and what effect such interventions might have on risk." In an editorial, Marianne Berwick, Ph.D., M.P.H., of the University of New Mexico in Albuquerque, and Paolo Vineis, M.D., M.P.H., of Imperial ...

University of Manchester makes made-to-measure skin and bones a reality using inkjet printers

...gment which will fit exactly. Wecan place cells in any designed position in order to grow tissue orbone."...ctlyinto the structure as it is built. This avoids any 'sticking to thesurface' which is a major disadvantage of current methods that infusethe cells into ...

Dysentery uses 'sword and shield' to cause infection

...dysentery, is able to invade cells, while stopping any response from the immune system. They found that shigella was able to infect cells by using a secretion system to inject proteins into human cells, (the sword), while lipopolysaccharide (LPS) on the surface of the bacteria acts as a shield to protec...

Novel technology detects human DNA mutations

...pecificity and sensitivity. One segment identifies any mutations in the DNA and the probe, a highly sensitive gold nanoparticle, creates a strong signal accurately indicating the presence of a specific target SNP. Proof of principle, reproducibility, and the robust, simple and rapid characteristics of th...

Topical treatment shown to inhibit HIV and herpes simplex virus infection

...tentially increase susceptibility to HIV and limit any protective effect of microbicides." said Betsy Herold, M.D., Professor of Medicine and Chief of Pediatric Infectious Disease at Mount Sinai and the senior investigator on this study. "We are currently conducting a 14-day study to assess whether or no...

Priming embryonic stem cells to fulfill their promise

...er researchers couldeasily use this technique with any other tissue in mouse, or human, orany other speci... number ofpossible combinations of these proteins, any one of which could formthe optimal "niche" for a desired type of differentiated cell.In their experi...

Growth in the sea comes down to a struggle for iron

...ts had recorded the largest phytoplankton bloom of any of the iron fertilization tests conducted to that ... not adding iron to ocean waters is a wise tool in any attempts to manage a changing climate. ...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

...ice that were not inbred or genetically altered in any way, they mated females with males, dating the day of their pregnancy, which lasts three weeks. They separated the mothers into two groups. The control group ate as much chow as they wanted during the entire pregnancy. The other group also was fully ...

Neuronal 'traffic jam' marks early Alzheimer's disease

... early in the life of those animals -- well before any plaque deposition -- were obvious axonal defects,"... scale toward disease." Goldstein emphasized that any application of these findings to potential diagnostic tests or new therapies remains speculative at ...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

... made during thelast few years to try to eliminate any animal-derived culturecomponents in human stem cel...mbryonic stem cellsthat have never been exposed to any animal products, and ideally, onlyever exposed to serum from the intended transplant recipient.""How...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...ound forms and try to understand whether there are any immunologic properties that differ and that might provide a route to new vaccine or drug strategies," Harrison says. ...

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

... knownas organelles," Holtzman explains. "Normally any given segment of anerve cell branch would have only very small amounts of theseorganelles."Nerve cells move organelles along their branches as a part of theirregular function. Holtzman suspects that this transport breaks down inthe mice, leading to p...

Key molecule in plant photo-protection identified

... knownas organelles," Holtzman explains. "Normally any given segment of anerve cell branch would have only very small amounts of theseorganelles."Nerve cells move organelles along their branches as a part of theirregular function. Holtzman suspects that this transport breaks down inthe mice, leading to p...

Timing is everything: First step in protein building revealed

...can the ribosome start making proteins."No one had any idea when eIF1 was released from the ribosome, or thatits release might serve an important purpose, so this was a completelyunexpected result," says graduate student David Maag, first author ofthe paper."It's impossible to know for sure whether eIF1 ...

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(Date:9/30/2014)... comes to using marijuana, new research, involving mice and ... Journal of Leukocyte Biology , suggests that ... you should. That,s because a team of Italian scientists ... serious long-term damage to the immune system. This damage ... such as multiple sclerosis, inflammatory bowel disease and rheumatoid ...
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(Date:9/30/2014)... -- Winners of The Economist,s prestigious Innovation awards 2014 ... place at the JW Marriott Hong Kong on Friday, October 10 ... their experiences and the lessons those hold for others. The awards, ... the past decade, will be presented at a ceremony in ... will be the first time the ceremony has come to ...
Breaking Biology News(10 mins):Adolescent exposure to thc may cause immune systems to go up in smoke 2Risky metabolism 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 3Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 4Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 5Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 6Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 7
(Date:10/1/2014)... protein beta-amyloid is strongly associated with Alzheimer,s disease; however, ... peptide is the causal agent of the onset and ... confirmation is that beta-amyloid is not harmful when found ... when it self-assembles to form the so-called amyloid fibrils ... beta-amyloid alone, but with multiple ones because each aggregate ...
(Date:10/1/2014)... new research study published today in the Journal ... patients older than 50 years with moderate or severe ... , Researchers from the University of Melbourne randomly assigned ... pain to no acupuncture or sham or pretend laser ... with participants and acupuncturists blinded to laser and sham ...
(Date:10/1/2014)... Physical Sciences Research Council (EPSRC) will focus on ... systems which run, for example, manufacturing plants, power ... , The research will help understand and ... systems behind our critical national infrastructure. , ... (RITICS), based at Imperial College London, is co-ordinating ...
(Date:10/1/2014)... BOSTON (October 1, 2014) Despite a policy ... with developmental disabilities, this vulnerable population continues to ... of The Journal of the American Dental ... Medicine and Tufts University School of Dental Medicine ... factors influencing at-home oral care provided by caregivers ...
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Breaking Medicine News(10 mins):Health News:Laying siege to beta-amyloid, the key protein in Alzheimer's disease 2Health News:Study finds acupuncture does not improve chronic knee pain 2Health News:£2.5 million to recognize and reduce cyber-attack threats to critical infrastructure 2Health News:To improve oral health of adults with developmental disabilities, support caregivers 2Health News:To improve oral health of adults with developmental disabilities, support caregivers 3Health News:Affordable Term Life Insurance - Senior Citizens Can Qualify for Coverage! 2
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