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Tag: "antiviral" at biology news

Federal grant funds research on novel HIV therapy

...a variety of ways. In addition to studying direct antiviral action, the researchers will also look for effects...in conjunction with existing HIV drugs, evaluating antiviral activity against HIV-infected cells. "Including a private sector partner is a way to strengthen the ...

New possibilities for flu antiviral and vaccine research emerge from 'Spanish flu' virus

... and then block it, perhaps it would be useful for antiviral development. With the identification of the polyme...noted some encouraging signs. The FDA-approved flu antiviral drugs, oseltamivir and amantadine, have been shown to be effective against viruses carrying certain ...

Agricultural workers at increased risk for infection with animal flu viruses

... in developing flu pandemic surveillance plans and antiviral and immunization strategies, according to the study's co-investigator, Gregory C. Gray, M.D., director of the University of Iowa Center for Emerging Infectious Diseases. "If migratory birds introduce the H5N1 bird flu virus into swine or poultry pop...

Preventing a pandemic: Study suggests strategies for containing a flu outbreak

...ferent scenarios. They found that targeted use of antiviral drugs could be effective for containment as long a... value of roughly 1.6. A process of administering antiviral drugs to the people in the same mixing groups as the infected person, called TAP for "targeted antiv...

Drug resistant avian influenza viruses more common in Southeast Asia than North America

... of avian flu viruses shows that resistance to the antiviral drug amantadine in H5N1 occurs worldwide, but is e...in China, according to St. Jude Resistance to the antiviral drug amantadine is spreading more rapidly among avian influenza viruses of H5N1 subtype in Southeast...

Researcher at UGA College of Veterinary Medicine identifies new way of combating viral diseases

... from reproducing and infecting other cells. Most antiviral therapies target the virus itself, but viruses are...utate rapidly and develop resistance to almost any antiviral compound. By focusing on the host cell while most scientists concentrate on the virus, Hodge and hi...

Learning how SARS spikes its quarry

...tential weak points that can be exploited by novel antiviral drugs or vaccines. The SARS (severe acute respir...s you an opportunity to explore the possibility of antiviral therapeutics," said Harrison. "When you have two conformational structures, you can think about how ...

Virus uses tiny RNA to evade the immune system

...ctions in T antigen expression promote escape from antiviral T cells without affecting virus growth. "Viruses ...y, which is often speculated to have evolved as an antiviral mechanism, to generate small RNAs that serve their own purposes -- the latest chapter in the long ca...

Biota makes major antiviral discovery

.... "The discovery of a novel, orally available RSV antiviral is a major achievement," said Dr Simon Tucker, Vice President of Research for Biota. "Others, including several large pharmaceutical companies, have discovered and disclosed RSV antivirals, but many are inhaled products. Orally effective RSV compound...

UIC developing drug for SARS

...drome, or SARS. Currently, there are no effective antiviral agents or vaccines for SARS, which killed almost 800 people in an epidemic in 2002-2003. On the basis of their success, the researchers have received an $8 million grant from the National Institute of Allergy and Infectious Diseases to develop prote...

Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development

..., infection of the host cell was inevitable. Thus, antiviral drug development has largely focused on preventing events that happen either before or after this step. However, a multi-institutional team of researchers is reporting that it has detected an intermediate stage between the virus' merger with the cel...

Quantum dots provide a faster, more sensitive method for detecting respiratory viral infections

... system. It can: * Increase the proper use of antiviral medicines. Although such medicines have been developed for some respiratory viruses, they are not used often as therapy because they are only effective if given early in the course of infection. By the time current tests identify the virus, it is gen...

Mass production of human papillomavirus could lead to gains against cervical cancer

...rs are hopeful that this advance could lead to new antiviral drugs and to vaccines that would trigger the immun...tion technique could offer a way to screen for HPV antiviral drugs and could lead to enhanced vaccines that consist of live attenuated virus. "Current vaccines i...

Retroviral resistance gene found

... transport machinery might reveal a new target for antiviral drugs in the treatment of HIV-1 disease." ...

Identification of specific genes predicts which patients will respond to Hepatitis C treatment

... genes in more detail will hopefully lead to novel antiviral treatments," said Dr. Ian McGilvray, the senior au...ed on are stimulated by interferon, one of the key antiviral agents that the body produces in response to viral infection and a medication that patients currentl...

Achilles heel of the herpes virus possibly found

... for herpes infection are badly needed; currently, antiviral drugs can quell symptoms of an outbreak, but not e... that B5 or its viral ligand could be a target for antiviral treatment, much like cell receptors for the entry of human immunodeficiency virus (HIV) into cells h...

Scientists discover how Ebola virus infects cells

...findings raise the possibility of a broad-spectrum antiviral therapy that could be effective against multiple h.... The authors write, "Further investigation of the antiviral efficacy of [enzyme] inhibitors may…be warranted. The wealth of existing knowledge regarding the des...

Gladstone investigators discover how resting T cells avoid HIV infection

...T cells are not. The team discovered that a potent antiviral factor called APOBEC3G (A3G) is the key. The team...vation process dismantles the highly effective A3G antiviral shield, making these cells highly susceptible to HIV infection. Greene's group is now looking at wa...

Study reveals candidate targets for anti-retroviral therapeutics

...f the AIDS virus, HIV, makes identification of new antiviral targets an urgent necessity. Host genes required to support the replication of HIV are a potential source of such novel targets, but relatively few appropriate target genes have been identified in animal cells thus far. A new study, conducted by Dr. ...

HIV-1 spread through six transmission lines in the UK

...he National Academy of Sciences, also suggest that antiviral therapy has not had a significant impact on the growth of the epidemic and that changes in sexual behaviour have been more effective in slowing the spread of the disease. The collaborative study led by University College London (UCL) scientists foun...

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