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Tag: "antitumor" at biology news

Researchers shed light on mechanism of action used by anti-cancer drug

...ogically combined with other targeted agents whose antitumor activity is limited by Mcl-1 expression,” Grant said. Several such targeted agents are currently undergoing clinical evaluation in patients with various malignancies....

Progress toward an antitumor vaccine

...molecule (antigen) for antibodies in immunological antitumor therapy. The difficulty with this approach is that such sugar-containing compounds are completely ineffective at stimulating the immune system to form antibodies. “Immunization is only successful if the vaccine is anchored to an immunizing carrier...

Navigable nanotransport

...ell. Here, the contents of the capsule, such as an antitumor drug or contrast agent, can be released to selectively attack the tumor or to make an unambiguous diagnosis. ...

Statin plus cancer drug deliver combo punch to brain cancer cells

...ng those signals with a statin and an experimental antitumor drug. The unlikely pairing of cholesterol-lowering lovastatin and cyclopamine killed 63 percent of medulloblastoma cells grown in the laboratory. By contrast, using either agent alone wiped out fewer than 20 percent of cells. The Hopkins researche...

VCU Massey Cancer Center researchers identify a new class of anti-cancer drugs based on platinum

...er cells were exposed to each drug. "In platinum antitumor chemistry our objective is to design and develop complexes acting by new mechanisms of action," said Nicholas Farrell, Ph.D., professor and chair in the Department of Chemistry at VCU, and lead author of the study. "Resistance to current drugs is due...

Turning viruses into allies against cancer

...ey inserted into the virus the gene for a powerful antitumor immunity stimulant called GM-CSF, (granulocyte macrophage colon stimulating factor). Its job is to induce an immune response to any surviving cancer cells released during the initial viral attack, essentially preventing the spread of these cells to o...

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