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Tag: "antifungal" at biology news

Discovery may lead to better Candidiasis drug

...e first time how histatin, the naturally occurring antifungal agent in saliva, kills the oral pathogen Candida a...enture wearers. The condition can be treated with antifungal medication in otherwise healthy people, said Edgerton, but it is difficult to treat in persons with ...

UF researchers kill resistant bugs one bandage at a time

... wound dressings or ready-to-wear clothing to make antifungal and microbicidal socks and underwear. "What we developed in the lab has to be able to be adapted into industrial manufacturing, and the breakthrough came when we figured out how to do that," Schultz said. Clothing that kills athlete's foot and othe...

Aloe vera coating may prolong freshness, safety of fruits and vegetables

...era gel appears to contain various antibiotic and antifungal compounds that can potentially delay or inhibit microorganisms that are responsible for foodborne illness in humans as well as food spoilage. Although the health effects of Aloe gel on human consumption were not directly measured in this study, th...

Secret sex life of killer fungus?

...t might evolve more rapidly to become resistant to antifungal drugs used to control disease; sexual reproduction might lead to new strains with increased ability to cause disease and infect humans. Nevertheless, the sexual cycle could be a useful genetic tool for scientists to use in their study of the mechanis...

MIT chemist discovers secret behind nature's medicines

...oorganism Pseudomonas syringae uses to produce the antifungal agent syringomycin, he discovered it had a single iron atom in the protein's active site, the part responsible for the chemical reaction. Drennan and her graduate student Leah C. Blasiak, who was first author of the study, crystallized SyrB2 and the...

Montreal researchers identify defects of immune cells

...ains of Candida albicans resistant to conventional antifungal therapies. The research project was carried out jointly by Dr. Louis de Repentigny, Director of the Medical Mycology Laboratory and Professor in the Department of Microbiology and Immunology at the Faculty of Medicine of Université de Montréal, and a...

U of M researchers discover genetic key to treating deadly fungal infections

...year in the United States overcomes the effects of antifungal drugs by duplicating a section of one of its chrom...have discovered that C. albicans can neutralize an antifungal drug by modifying one of its own chromosomes. The cell duplicates one arm of chromosome 5 and delete...

Anti-fungal drug stops blood vessel growth

... pharmacology. “We couldn’t have predicted that an antifungal drug would have such a role.? In their search fo... appears online in ACS Chemical Biology. As an antifungal drug, itraconazole blocks a key enzyme for making fungal cholesterol, causing these primitive life f...

Antifungal drug kills TB bug

... chemicals called azoles ?the active agent in many antifungal drugs ?kill the TB bacteria, and could be effective in tackling the emerging drug-resistant strains. "TB is back with a vengeance with a third of the world’s population currently infected," said Professor Andrew Munro, who led the research in Manc...

New recommendations against a major opportunistic infection -- cryptococcosis

...tion of cryptococcosis according to the particular antifungal drugs used. In light of all of the factors analysed, the authors advocate that all patients in whom a diagnosis of cryptococcosis has been established should have an assessment of their fungal load to evaluate the severity of the disease. Accor...

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