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Tag: "antidepressants" at biology news

New brain-chemistry differences found in depressed women

...kground. The women with depression were not taking antidepressants when the study began. "This work gives further evidence of individual differences in brain mechanisms that are altered in major depression," says senior author Jon-Kar Zubieta, M.D., Ph.D., the Jenkins Research Professor of Depression and associat...

Ever-happy mice may hold key to new treatment of depression

...k-out' mice acted as if they had been treated with antidepressants for at least three weeks." This research represents the first time depression has been eliminated through genetic alteration of an organism. "The discovery of a link between TREK-1 and depression could ultimately lead to the development of a new g...

Suicide risk does not increase when adults start using antidepressants, study finds

... than 65,000 patients who filled prescriptions for antidepressants from 1992 to 2003. Deaths by suicide were determin...subsequent months. The study also found that newer antidepressants were associated with a faster decline in rates of suicidal behavior than older drugs. Adolescents i...

Nobelist discovers antidepressant protein in mouse brain

... brain cells by administering to mice two types of antidepressants ?a tricyclic, a monoamine oxidase (MAO) inhibitor ...ect." Future studies should elucidate exactly how antidepressants increase levels of this molecule, he added. Also participating in the study: Per Svenningsson, Ilan...

Mice lacking social memory molecule take bullying in stride

...rning is shaped by psychosocial experience and how antidepressants act in this particular brain circuit. They also su...genes turned on and off by social defeat, BDNF and antidepressants revealed the workings of the molecular pathways involved in dopamine regulation of social motivation...

It's in the genes: Study opens door to new treatment of the blues

...ve made great progress in our understanding of how antidepressants work, but despite years of research, our knowledge of the changes that these drugs induce in the brain is rudimentary," Bolanos said. "Though available treatments for depression are generally safe and effective, they are still not ideal. It takes lon...

How 'hot' emotional brain interferes with 'cool' processing

...e kinds of studies to determine whether particular antidepressants influence the response of that ventral system. And what is particularly exciting is that this method allows us to look directly at the neurological target of the drug and not have to try to measure the more nebulous behavioral response. So, we can de...

Commonly used antidepressants may also affect human immune system

... of pleasure, mood, and appetite, and the class of antidepressants known as SSRIs keeps serotonin active within the synaptic spaces between neurons, enhancing the chemical's positive effects. Unlike in the brain, which uses chemical messengers to communicate between nerve cells, the immune system is believed to "con...

In SAD patients, autumn antidepressants can prevent winter depression

...actually be prevented in some patients by starting antidepressants early in the season, before the development of symptoms," comments Norman E. Rosenthal, M.D., Clinical Professor of Psychiatry, Georgetown Medical School, and one of the authors of the paper and leader of the research team that first described SAD ov...

Diabetic nerve therapy shows 'striking' results

...rrently, patients are treated with painkillers and antidepressants that do not treat the underlying nerve damage. Progression to amputation is not inevitable but is always a threat. Problems may also occur in other organs, including the heart, kidneys, sex organs, eyes and digestive tract. The incidence of diabete...

Depression gene may weaken mood-regulating circuit

...n cells. Since the most widely prescribed class of antidepressants act by blocking this protein, researchers have focused on possible functional consequences of a slight variation in its DNA sequence across individuals. Everyone inherits two copies of the gene, one from each parent, which comes in two common version...

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