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Tag: "antibodies" at biology news

Pregnant mom's exposure to flu vaccine kick-starts fetal immune system

... and Prevention. The authors detected anti-Fluzone antibodies in approximately 40% of cord blood specimens examined. These results and further data reported in the study establish that B and T cell responses to antigens occur in utero following maternal vaccination against influenza, supporting the theory that ...

The insect vector always bites twice

...ions living in transmission areas, the presence of antibodies targeting specifically these proteins contained in...ven region. In Senegal the rate of antisalivary antibodies against Anopheles in young children (under 5 years), the population most exposed to the risk of mala...

Breakthrough developments in rheumatoid arthritis reported

... of how the immune system works to create specific antibodies that in turn increase a person’s risk for this cri... Scientists are now finding that patients have CCP antibodies months or years prior to the illness, suggesting a way to identify the disease before it starts and ...

Newly discovered antibody may be body's natural defense against Alzheimer's

...Medical Center have identified naturally occurring antibodies in human blood that may help to defend against thi...ther neurodegenerative diseases. The newly found antibodies selectively target aggregates of beta amyloid proteins called "oligomers" that are toxic to brain ce...

Progress toward an antitumor vaccine

...MUC1 would be a good target molecule (antigen) for antibodies in immunological antitumor therapy. The difficulty with this approach is that such sugar-containing compounds are completely ineffective at stimulating the immune system to form antibodies. “Immunization is only successful if the vaccine is anchor...

Blood-brain barrier breached by new therapeutic strategy

...terference therapy did not trigger inflammation or antibodies to the peptide. Currently, doctors use various methods to deliver therapeutic drugs directly into the brain. These methods involve invasive procedures that result in only localized delivery around the site of injection. The new research provides ...

How 'memory' T cells curb the spread of viruses throughout the body

...se. While scientists have long known the role of antibodies in protection, whether memory cells, known as CD8 T cells, could prevent viral diseases has been debated. The new work by Fox Chase virologist Luis J. Sigal, D.V.M., Ph.D., and his Fox Chase colleagues in the virology and pathology programs, provide...

Avian influenza survivors' antibodies effective at neutralising H5N1 strain

... Medicine, the researchers have shown how specific antibodies taken from avian flu survivors in Vietnam can be r...seases in Bethesda, US, have shown that monoclonal antibodies generated from blood of human survivors of the H5N1 virus are effective at both preventing infection...

HIV and malaria combine to adversely affect pregnant women and their infants

...tas. They found that HIV-infected women lose these antibodies and again become susceptible to the ravages of PAM. The findings, according to Kain, may help in the development of PAM vaccines. "This is only the first step in creating therapeutics to treat this devastating disease," he stresses. "We hope to he...

Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism

...ed in the vascular lesion is of autoimmune origin: antibodies directed against particular proteins of the virus ...disease. This new study therefore confirms that antibodies directed against Cytomegalovirus-derived proteins purified from patients with coronary artery diseas...

New study suggests potential for a broadly-protective HIV vaccine

...ed to stimulate the body to produce cross-reactive antibodies that will neutralize multiple viral strains. These...hat induction of truly broad-spectrum neutralizing antibodies may be an achievable goal. This groundbreaking study titled: “Extensively Cross-Reactive Anti-HIV-1 ...

Better insight into brain anatomical structures

... Furthermore, the Korean team was able to attach antibodies to the manganese oxide nanoparticles. These antibodies recognize and specifically bind to receptors on the surface of breast cancer cells. In mouse brains ...

Resistant HIV quickly hides in infants' cells

...ed out, "since transplacental transfer of maternal antibodies precludes the use of antibody detection methods." Affordable techniques also are necessary to reliably detect resistant HIV in less affluent areas of the world. SUGGESTED "FAST FACTS": Five of 21 HIV-positive infants in this study were...

Vaccine prevents prion disease in mice

...ided into two groups ?those who had high levels of antibodies in their blood and thus responded well to the vacc...ls of antibodies. The mice with high levels of antibodies had no symptoms of the disease after 400 days. The mice with low levels of antibodies also had a sig...

Risk of lymphoma increases with hepatitis C virus infection

..., a condition marked by abnormal levels of certain antibodies in the blood, was also elevated for those with HCV infections. The researchers looked at patient records collected from Veterans Affairs (VA) hospitals across the United States between 1996 and 2004. Researchers selected more than 700,000 records; ...

LIAI scientists make important finding on cytomegalovirus transmission

... ?and in some cases eliminated ?through the use of antibodies to enhance the disease-fighting power of the immune system. The research team’s findings, based on controlled laboratory studies of mice, may also have implications for other chronic virus infections, such as hepatitis and HIV, the virus that causes...

Researchers attach genes to minichromosomes in maize

...erm) can be used to grow animal proteins and human antibodies that treat diseases and disease symptoms. Minichromosomes could enable new and better production of these foreign proteins and antibodies. In addition, scientists also may be able to use them to develop plants better suited for biofuel production. ...

The quest for an effective HIV vaccine presents new possibilities, challenges

...substantially. Further, the effectiveness of these antibodies is stymied because of the rapid genetic changes th...stablishment of HIV infection. Although rare, such antibodies do exist, giving hope to scientists that a vaccine to induce such antibodies can be designed. Dr...

A new portable biosensor detects traces of contaminants in food more quickly and cheaply

...y. The organism attacks an infection by generating antibodies which hook onto, for example, a specific type of v...e eliminated. In the case of the sensors, specific antibodies for atrazine have been used (in the case of pesticides) and for sulphanilamide (in the case of ident...

Biodegradable microspheres deliver time release vaccines, stimulate different immune response

... Meeting. "Current vaccines are good at producing antibodies that block entry into the cell. In the case of so...cells that have already become infected, something antibodies can not do. The determine the cause of this effect, Wilson-Welder and her colleagues next incubat...

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(Date:10/30/2014)... – When most animals begin life, cells immediately begin ... vital organ. However, mammals, including humans, are special. The ... first choice – to become the protective placenta or ... this critical first step that research from Michigan State ... the current issue of PLOS Genetics ...
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