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Tag: "antibiotic" at biology news

Learning to fight an adversary that won't stay down

...ng bacteria, says a leading Canadian specialist in antibiotic resistance. Techniques such as genomic sequencing...ening were expected to make the development of new antibiotic compounds easier and more productive. But in most cases the microbes continue to hold the upper hand...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...originally believed to be involved in tuberculosis antibiotic resistance is actually a "missing enzyme" from the... the M. tuberculosis genome have been annotated as antibiotic resistance genes due to their sequence similarity to existing antibiotic resistance genes. Dr. Edwar...

U of M researcher examines newly emerging deadly disease

...nts who present symptoms of purpura should receive antibiotic therapy not only against Neisseria meningitidis and streptococci, but also against methicillin-resistant S. aureus (MRSA), with the consideration that the staphylococcal disease may be more common than the two prior illnesses. Patients should also be...

Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey

...ll, antibiotics. Tens ofthousands of deaths due to antibiotic resistant infection occur eachyear in the US, adding an estimated $ 4 Billion to health care costs.Scientist have known since 1934 that especially harmful strains ofEnterococcus produce a toxin that destroys other cells, including humancells and even...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...treptomyces bacterium -- the bug that gives us the antibiotic streptomycin -- also produces a natural compound called migrastatin, which appears to inhibit cell migration. Natural migrastatin's effect is relatively weak, but Dr. Huang suspected the molecule might be manipulated into something more potent. In c...

Sequencing of marine bacterium will help study of cell communication

...raction regulates bacterial processes that include antibiotic or toxin production, biofilm formation, and bioluminescence. One of the longest studied models of quorum sensing is the bioluminescent marine bacterium V. fischeri. "It was selected by Drs. Ruby and Greenberg to be sequenced exactly because it is so...

Antibiotic might fight HIV-induced neurological problems

...Johns Hopkins researchers have discovered that the antibiotic minocycline might help alleviate HIV's negative ef...e brain. Other researchers have reported that this antibiotic can protect brain cells in animal models of other diseases -- multiple sclerosis, amyotrophic latera...

Artifical cornea lets woman blind 20 years see

...y patient must adhere to a strict daily regimen of antibiotic eye drops. With regular maintenance ?including visits to the ophthalmologist at least every three months (more frequently immediately after surgery) ?complications can be kept to a minimum, she said. Because of the intensiveness of the lifetime commi...

Drug-resistant bacteria on poultry products differ by brand

...aries by commercial brand and is likely related to antibiotic use in production, according to researchers at the... those who claim they do not. The study focused on antibiotic resistance, specifically fluoroquinolone-resistance in Campylobacter, a pathogen responsible for 2.4...

Substance protects resilient staph bacteria

...ublic health problem made worse by the increase in antibiotic resistance," says NIAID Director Anthony S. Fauci,...s S. epidermidis from innate immune defense, human antibiotic compounds and salt concentrations similar to levels found on human skin. Dr. Otto's group also used ...

PGA on a tour under the skin

...ement heart valves, and intravenous catheters, and antibiotic resistance makes it tough to battle. Moreover, the mechanism through which the organism becomes so pathogenic once the protective barrier of the skin is removed remains unclear. In their study appearing online on February 3 in advance of publication...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

...e increasingly adept at outwitting the traditional antibiotic arsenal. Yet designing and testing new antibiotic...rror approach that can take years. “About one new antibiotic a year is approved,?said Derendorf, who will discuss the technique Saturday (March 5) at the annual ...

Researchers make gains in understanding antibiotic resistance

...itute researchers chiseling away at the problem of antibiotic resistance now have a detailed explanation of how ...c chemical principles that underlie binding of the antibiotic to the ribosome, as well as new data about how that mutation confers drug resistance. Steitz and hi...

UNC launches study of liver injury caused by drugs

...e medications phenytoin and valproic acid, and the antibiotic amoxicillin-clavulanate potassium. "Eligible patients from anywhere in North Carolina or neighboring states who are willing to come to UNC can be enrolled now," Watkins said. "Overall, we believe that the network will bring greater focus and interes...

Measuring hormone cuts antibiotic use in half in pneumonia patients

...in Basel, Switzerland. "Because of concerns about antibiotic resistance, as well as the cost of antibiotics, it...ng levels of the hormone could eliminate or reduce antibiotic use in patients with bacterial pneumonia. Results of the blood test that measures procalcitonin leve...

OneWorld Health drug receives 'Orphan' designation from U.S. and European regulatory agencies

... VL." Paromomycin is an off-patent aminoglycoside antibiotic first used in the 1960s and is still marketed in the U.S. as an oral formulation to treat intestinal parasites. The largest-ever Phase III clinical trial for visceral leishmaniasis was completed in November 2004 by OneWorld Health in collaboration wi...

Symbiotic bacteria protect hunting wasps from fungal infestation

...y provide insight into strategies for dealing with antibiotic resistance in our own species's efforts to combat harmful microbes. ### Martin Kaltenpoth, Wolfgang Göttler, Gudrun Herzner, and Erhard Strohm: "Symbiotic Bacteria Protect Wasp Larvae from Fungal Infestation" The other members of the research team...

Stanford gut check shows diversity of intestinal ecosystem

...vities they have pursued in terms of travel, diet, antibiotic use and the like. Relman emphasized that the study looked at only a limited number of individuals and examined only one genetic feature of the microbes, so there are many studies that must and will follow. It took the team about a year to carry out...

To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists

... Wisconsin have demonstrated a new way of fighting antibiotic resistance: by stopping evolution. In the June is...s of death in the United States. But then came the antibiotic revolution. Antibiotic "wonder drugs" toppled tuberculosis (TB) and typhoid fever, controlled choler...

Where bacteria get their genes

...nsfer, is the way many pathogenic bacteria pick up antibiotic resistance or become more virulent. "To maintain effective treatments and develop new antibiotics, it's important to monitor the rates and patterns of lateral gene transfer," said team member Howard Ochman, a UA professor of biochemistry and molecul...

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