Secret of smallpox's success may lead to bioterror cure
...ularly lethal strain of vaccinia, or to mouse pox, another pox virus. "We want to look at all of our mutants and see which ones work best in this post-exposure prophylaxis," explained Jacobs. Though results are preliminary, several strains look promising. Jacobs' experimental results verify that the de-clo...Basis for DNA ejection from single phage particles
...tion of the DNA during morphogenesis ?for example, another group recently showed that the pressure at the final stage of encapsulation for a particular bacteriophage reached a value of 60 atomospheres, which is close to ten times the pressure inside a bottle of champagne. In the new work reported this week, ...The circadian clock: Understanding nature's timepiece
...er of the prestigious Trends in Neurosciences, and another is due out in a forthcoming issue of the Journal of Neurosciences. "There are enormous health, safety and economic benefits to figuring out how the circadian clock works," Antle says. "We are probably still at least 10 years away from developing a p...Scientists discover how Ebola virus infects cells
...opped to near zero. An accessory role is played by another cellular enzyme, cathepsin L, the scientists determined. Inhibitors of cathepsins are already under clinical development as anti-cancer drugs. The authors write, "Further investigation of the antiviral efficacy of [enzyme] inhibitors may…be warrante...Finding hidden invaders in a Hawaiian rain forest
...ng the new aircraft-based techniques: they located another invader, the Kahili ginger plant (Hedychium gardnerianum), growing under the forest canopy. Ginger cannot be detected from above the forest canopy using traditional aircraft or satellite approaches, but the new methods are sensitive to its high water...Stem cell research - new cell lines
...layers ?one which forms the brain and spinal cord, another which forms the guts and liver and a third which forms muscles and bones," he said. "We need to establish a recipe to derive each of these from human embryonic stem cells, so they can be transplanted straight into the affected area of a patient. "Th...Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics
...he current through it as electrons were removed by another electrode, turning it from an insulator to a strong conductor and then back into an insulator again. Given the measured electrical properties of the oligoaniline, Lindsay notes that if the molecule is maintained at its highly conductive state (at lo...A New Species of Monkey is Discovered in Tanzania: The First in Africa for More Than 20 Years
...ution. Ehardt observes that, “With the addition of another threatened species of primate to those species previously documented, the Udzungwa Mountains are arguably the most important site in Africa for primate conservation. The Udzungwas remain a focus for conservation ecology research, as should the South...Mouse with designer liver has enhanced glucose tolerance, insulin response
...tivity of IRS proteins. There was no activation of another enzyme, Erk, which is elevated in normal liver in reaction to insulin stimulation. Dr. Feng concluded that the function of Gab1 in normal liver cells is to promote signaling in the Erk pathway, which reduces insulin response signals flowing through I...Thai spice helps cut blood sugar swings
...ogy at the University of Zurich, Switzerland, said another promising area "we plan to study is HCA's affect on food intake reduction, since it is known that HCA seems to reduce some food intake in rodents." ...Nature provides inspiration for important new adhesive
...ein that could be adapted for this purpose, Li had another inspiration at lunch - while eating tofu. "Soy be... companies, researchers say. They can also provide another market for the nation's soybean farmers - the new adhesives use a tremendous amount of soy flour. ...To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists
...ymes, which are tasked with recombining the DNA -- another way to repair it. And, says Romesberg, if the damage still persists, the cells upregulate enzymes whose sole task is to make mutations. Presumably, inducing mutations is an effective evolutionary strategy for dealing with environmental changes that ...Hydrogen and methane provide raw energy for life at 'Lost City'
...fish. Kelley will be co-principal investigator on another science expedition to Lost City this summer, witho...during the journey. Although nobody has yet found another field like Lost City, Kelley says she's 100 percent sure others exist because there are so many othe...15-year hunt finds cause of pseudothalidomide syndrome
... pull the original and the new copy away from each another as division proceeds. However, in cells from people with Roberts syndrome, the chromosome copies are frequently not attached to each other at their centromeres and the chromosomes don't get lined up properly. As a result, the cell doesn't divide or ...Gov't Creates Gene Database of Normal Human Tissues
...e. "All of these genes are involved in one way or another with the kinds of activities associated with the development of cancer -- processes such as apoptosis, growth, proliferation and transcription," said Khan. These results provide scientists studying and treating NB with a focused set of genes to explo...Remote control flies? Fly behavior controlled by laser light
...rchers concluded. Lima and Misenböck also equipped another set of nerve cells called dopaminergic neurons with the remote controls, boosting the flies' activity levels and changing their flight paths. Misenböck says the triggered behaviors can last seconds or continue for minutes, depending on whether the n...Internet viruses help ecologists control invasive species
...y water flea. Earlier work by the pair found that another lake in the network, Lake Muskoka in central Ontario, has served as the hub from which 39 other lakes have become infected since 1989. "It quickly developed into a regional hub for two reasons. First, all of its outbound traffic was to non-invaded la...Insects, viruses could hold key for better human teamwork in disasters
...n drives decision-making," Hollingshead said. Put another way, while individual honeybees process only "partial and local information," they are able, through interactions with each other, to produce "a coherent response to a change in their environment," said Robinson, an expert on honeybees. To date, no ...Single-donor Islet Transplantation Procedure Shows Promise For Patients With Type 1 Diabetes
... only 1 donor pancreas [as compared with 2 to 4 in another trial], we also achieved superior glycemic control (as evidenced by normal results of oral glucose tolerance testing in 4 of 5 recipients with sustained insulin independence) using significantly fewer islets," the authors write. "These findings may h...Precise Timing Enabled Pig-to-rat Transplants To Cure Diabetes
...uppression after transplanting from one species to another was such an unexpected and encouraging discovery that we wanted to find out more about why that worked and under what conditions it is possible," Hammerman says. Superficially, there appears to be relatively little difference between pancreatic prim...