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Tag: "annotation" at biology news

New findings challenge established views on human genome

...t before,” said Ewan Birney, Ph.D., head of genome annotation at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EBI) in Hinxton, England, who led ENCODE’s massive data integration and analysis effort. The ENCODE consortium’s major findings include the discovery that the major...

Exploring the dark matter of the genome

...ne 15, 2007 issue of Science. "The release 5.1 annotation of Drosophila melanogaster heterochromatin," by Christopher D. Smith, ShenQiang Shu, Christopher J. Mungall, and Gary H. Karpen appears in the June 15, 2007 issue of Science. ...

Genome of yellow fever/dengue fever mosquito sequenced

...plains, "An important part of this project is gene annotation which predicts numbers and locations of mosquito genes in the genome. In parallel to sequencing DNA in chromosomes, scientists have also sequenced large amounts of messenger RNAs collected from different mosquito tissues at distinct developmental sta...

Beyond the DNA: Chemical signatures reveal genetic switches in the genome

...s an important step towards large-scale functional annotation of 'enhancers,' which establish the rate at which gene expression occurs and determine the tissues in which genes are expressed. "The human genome is packaged within each cell by chromatin, a structure composed of DNA wrapped around proteins calle...

Application of Genomatix in silico methods reveals novel cancer associated genes

...Two years ago we introduced our own concepts of an annotation and biology driven microarray analysis pipeline, and were heavily contested in the beginning. Today it is so rewarding to our scientists and developers to see the impact of our own ideas and research to cutting edge science of today." ...

Scientists perform 'tricky' operation

...stitute for Genomic Research (TIGR) and subsequent annotation of the genome database has opened many avenues of ...ion to the project involved the identification and annotation of several large families of genes related to those involved in various mechanisms of antimicrobial ...

Sequencing of the oyster mushroom genome

...rticipating laboratories in order to carry out the annotation of the genome sequence ?involving the identificati...he reading of the genome will be completed and the annotation of the genes perfected. In the end, all the information will be placed at the disposal of the scient...

When the going gets tough, slime molds start synthesizing

...ollowing the recently completed final assembly and annotation of the entire Dictyostelium genome, which was carried out by a worldwide collaboration of many scientists, including the Kay group. Working independently, Saito and Kay had deleted the Dictyostelium gene for Steely2. Not only could the resulting "...

DOE JGI releases IMG 1.5 with curated archaeal genomes

...hrough the gene details page and to propagate this annotation to selected paralogs, orthologs, and homologs of the gene. User interface extensions include such enhanced comparative analysis capabilities as gene profiles across genomes. For more details on the user interface, see What's New ( http://img.jgi.doe....

Virginia Bioinformatics Institutes launches microbial database

... (Vol.34, D379-D381), contains genome sequence and annotation data for the plant pathogens Phytophthora sojae an... is an integrated resource that includes community annotation features, toolkits, and resources to perform complex queries of biological information. The project'...

MBL leads effort to update E. coli genome

...p of 19 scientists from four countries updated the annotation of E. coli K-12 at two MBL workshops organized by ... database, but to present a comprehensive, updated annotation of E.coli K-12, which would be readily available to the public. "Our work puts a searchlight on the ...

Setting the standard for computer models of life

... to all the relevant metabolites. The aim of these annotation schemes is to make it easier for researchers to search models on the basis of their components, to contact the creators of the model if they need more information, and to track the history of a model if it has been modified. MIRIAM's creators inclu...

US/African project deciphers deadly parasite genome

... the genome sequence of T. parva and shared in the annotation of the genome ?the identification of genes and the...ne functions ?with scientists at ILRI. Much of the annotation of the T. parva genome was performed by two bioinformatics specialists at ILRI. "ILRI's involvement...

Possible treatment found for 'chemobrain'

...rtant because its sequence will aid in comparative annotation of the genomes of other roundworms that have been sequenced, including that of Caenorhabditis elegans, one of the most important model systems for understanding animal development. In addition, Heterorhabditis bacteriophora is widely used as a biolog...

NHGRI Selects 13 More Organisms for Genome Sequencing

...rtant because its sequence will aid in comparative annotation of the genomes of other roundworms that have been sequenced, including that of Caenorhabditis elegans, one of the most important model systems for understanding animal development. In addition, Heterorhabditis bacteriophora is widely used as a biolog...

Hunt for human genes involved in cell division under way

...because of the enormous cost and the ever-changing annotation of the human genome. But being part of the large EU project MitoCheck allowed us to work with one of the leading suppliers of siRNAs, Ambion Europe, Ltd., to produce a genome-wide library for this project," says Dr. Jan Ellenberg, EMBL Group Leader a...

Program finds lost genes in nematode genome

...ack in 1998. Nematode researchers rely on a genome annotation database called WormBase. Along with confirmed gen...roach to gene prediction stands traditional genome annotation on its head because it starts with a computer analysis of the genome sequence, using that as a hypot...

DOE JGI launches IMG public online microbial genome data clearinghouse

...low the scientific community to participate in the annotation effort. "There are hundreds of bacterial genome sequences in multiple databases with hundreds of new genomes expected this year," said Gary Andersen, Molecular Microbial Ecology Group Leader of the Lawrence Berkeley National Laboratory Earth Science...

B-15A collides with Antarctic ice tongue

... time released the chip design, probe sequence and annotation information for all of its microarrays. The release of this information is expected to improve cross-laboratory experimental research and cross-platform data comparison. "Full release of the probe sequences is an admirable and responsible position f...

Virus-host interactions at sea effect global photosynthesis

... time released the chip design, probe sequence and annotation information for all of its microarrays. The release of this information is expected to improve cross-laboratory experimental research and cross-platform data comparison. "Full release of the probe sequences is an admirable and responsible position f...

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(Date:7/9/2014)... of increasing concern about the prevalence of antibiotic-resistant ... promising new pathway to disabling disease: blocking bacteria,s ... scientists showed how bacterial siderophore, a small molecule, ... fan bacterial growth as well as how ... infection process. Their findings appear in a recent ...
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(Date:7/9/2014)... re-examination of a sparrow-sized fossil from China challenges the ... dinosaurs that gained the ability to fly. The birdlike ... but much rather the remains of a tiny tree-climbing ... of the Dinosaur Museum in Blanding, Utah, and Alan ... appears in Springer,s Journal of Ornithology . , ...
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(Date:7/9/2014)... Allergy and Infectious Diseases (NIAID), part of the ... clinical trial of CRS3123, an investigational oral antibiotic ... C. difficile ) infection. CRS3123 (previously known as ... difficile growth while sparing normal intestinal bacteria. , ... 30 healthy men and women ages 18 to ...
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