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Tag: "annotated" at biology news

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...ans of DNA in the M. tuberculosis genome have been annotated as antibiotic resistance genes due to their sequen... is the same or similar." Rv1347c is one of these annotated antibiotic resistance genes in M. tuberculosis. It encodes a putative aminoglycoside N-acetyltransfe...

Sequencing of marine bacterium will help study of cell communication

...ven the opportunity to be members of the team that annotated the sequence." Annotation is a complex process that assigns functions to genes. Having access to the genetic sequence in order to perform this chore gave Stevens and Faini early access to specific information about the genes of the bacterium she has...

Expression Project for Oncology (expO) completes first phase of standardized gene expression analyses

...roject for Oncology (expO) has released clinically annotated gene expression profiles for 60 tumor specimens, c... standardized gene expression data. The clinically annotated dataset is available in the public domain through the National Center for Biotechnology Information ...

Ariadne Genomics Announces the Release of PathwayStudio?Central, Client-Server Software for Biological Pathway Analysis

...tionships for human, rat and mouse contains 52,000 annotated mammalian proteins, 40,000 chemicals, and over 500 thousand total functional relationships, among which there are 42,000+ physical protein-protein interactions, 46,000+ facts of gene expression regulation, and about 160,000 links between 1779 human d...

A new way to share models of biological systems

...launch of BioModels, the world's first database of annotated biological models. BioModels is the result of a collaboration led by the European Bioinformatics Institute (UK) and the SBML Team, an international group that develops open-source standards to describe biological systems. Other contributors include t...

Gene Bridges And Covalys To Develop Restriction-Enzyme-Free SNAP-tag Gene Fusion Kits

...ures of molecular biology. Most online genomes are annotated with readily available BACs, so that it is easy to identify and obtain a BAC encoding a gene of interest. The new SNAP-tag kits will combine the inherent advantages of BACs with the power of SNAP-tag for protein expression studies." The cloning kits...

Setting the standard for computer models of life

... model of alcohol metabolism in the liver would be annotated with links to the protein databases for all the enzymes involved in this pathway, and database links to all the relevant metabolites. The aim of these annotation schemes is to make it easier for researchers to search models on the basis of their comp...

Where 'jumping genes' fear to tread

...discovered that many (85%) overlapped at least one annotated gene and that almost all (94%) overlapped at least one known RNA transcript. In addition, the TFRs were enriched in microRNAs, in genes that encode proteins with putative DNA-binding activity, and in genes that are involved in developmental processe...

Cure for cancer one step closer

...d collection of ethically consented and clinically annotated tissue, helping to unravel the cause, progression and potential treatment for cancer and other diseases. Professor Julie Campbell AO, Director of The Wesley Research Institute, said the current absence of large, high quality cancer tissue and bloo...

Human genetic 'deserts' are teeming with significant life

...ssenger RNA] outside the current boundaries of the annotated genes ”, Professor Reymond will say. He and his team are among the many international collaborators working together on a pilot project to use as a ‘reference set’ by the ENCODE consortium, launched in 2003 by the National Human Genome Resear...

Exploring the dark matter of the genome

...ers in the June 15, 2007 issue of Science. The annotated heterochromatic sequences reveal over 200 protein-coding genes. The heterochromatin also includes other features of biological importance, including sequences that code for non-protein-coding RNAs and other functional elements, such as small RNAs tha...

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