Structure-building cell signals also may influence learning and memory
... synapse function. Previous studies had shown that animals injected with addictive drugs had activated EphB receptors, and that there is a connection between synaptojanin-1 and bipolar disorders and schizophrenia. Until now, nobody had made the connection between EphB and the endocytosis involved in neurotra...Wake Forest scientists find new combination vaccine effective against plague
... around their environment. Thus it is possible for animals that have been exposed to a different bacterial in...agues found that flagellin is equally effective in animals with such antibodies as it is in mice that had never encountered flagellin before. "Prior immunity ...Radio-tracking associated with 'dramatic shift' in water vole sex ratio
... warned that radio-tracking could be affecting the animals they are studying. According to new research published today in the British Ecological Society's Journal of Applied Ecology, fitting radio-collars to water voles was associated with a "dramatic shift" in the sex ratio of the animals' offspring, casti...15-year hunt finds cause of pseudothalidomide syndrome
... a gene called ESCO2 that was identical in all the animals contained changes that disrupted the gene's protein-making instructions in people with the syndrome. Knocking out the equivalent gene in yeast and fruit flies led to the same chromosome problems, says Gordillo. "Comparative genomics didn't really ex...NHGRI targets 12 more organisms for genome sequencing
...l use the genome sequences of the 11 non-mammalian animals to learn more about how, when and why the human ge...rate evolution. Other innovations in this group of animals include an adaptive immune system similar to that of humans, a closed and pressurized circulatory sy...Ebola virus: from wildlife to dogs
...ng the latest epidemics, which suggests that these animals may well have been infected and can therefore be a...ondary way, through contact with carcasses of dead animals (2). However, the virus's natural cycle is not restricted just to transmission from the reservoir to...Researchers test new therapy for advanced melanoma
...herapy -- their tumors disappeared and the treated animals remained disease free for the full length of the study (100 days), Dr. Heller said. Furthermore, he said, even when melanoma cells were reinjected into the cured mice the tumors were rejected. This indicates the immune system formed a memory respons...Scientists use manufacturing methods to reconstruct mastodon
...ans sometimes butchered the massive, elephant-like animals and hauled off whole hunks of meat, often with the bones, says U-M mastodon authority Daniel Fisher, a professor with joint appointments in the Museum of Paleontology and the departments of Geological Sciences and Ecology & Evolutionary Biology. ...Active Vaccine Prevents Mice From Developing Prion Disease
...munization can protect a significant percentage of animals from developing symptoms of prion disease, explain...ct livestock, since most prion infections occur in animals and are thought to be transmitted orally, explains Dr. Wisniewski. The version of prion disease that...NYU, Rockefeller researchers find complexity of regulation by microRNA genes
... rise to the diversity of regulatory mechanisms in animals and plants. ...Research may provide new link between soft drinks and weight gain
...ater and soft drinks--despite that fact that these animals decreased the amount of calories they consumed fro...r than in the other groups, except for the control animals provided with water only. "We were surprised to see that mice actually ate less when exposed to fru...Census of Marine Life explorers surprised by diversity, density of Arctic creatures
...ies of large Arctic jellies, squid, cod, and other animals have been found thriving in the extreme cold, than...r higher than expected "Overall, the densities of animals are much higher than expected," says Census researcher Dr. Bodil Bluhm of the UAF. "It now appears p...Researchers reveal secrets of flying snakes
...avior of flying snakes, and found that the smaller animals were better gliders. "Despite their lack of wing-...dies through the air. "Although all of these other animals may make small adjustments while gliding, none are as dramatic, rhythmic and dynamic as the flying s...Researchers discover key gene involved in bark beetle pheromone production
...rfumes. It had been thought that insects and other animals were incapable of making these substances. "The goal of our research is ultimately to control pheromone production," said Gary Blomquist, professor and chair of biochemistry and molecular biology, who co-authored with several members of his departme...Discovery of New Dopamine Action May Yield Alternative Psychiatric Drugs
...amine. In addition to the behavioral deficits, the animals also lack normal regulation of Akt, they report. "These results provide direct physiologically relevant evidence for the emerging concept that beta-arrestin 2 not only controls desensitization but also participates in slow synaptic transmission here...Scientists discover global pattern of big fish diversity in open oceans
...Myers. "Like Goldilocks and the three bears- ocean animals don't like it too hot, or too cold, they like it j... studies show surprising congruence. "The smallest animals in the ocean and some of the largest show the same pattern of diversity at the global scale," says S...MIT engineers an anti-cancer smart bomb
...e best current therapy survived 30 days. Untreated animals died at 20. "It's an elegant technique for attacking the two compartments of a tumor, its vascular system and the cancer cells," said Judah Folkman of Children's Hospital Boston. "This is a very neat approach to drug delivery," said MIT Institute Pr...Excess liver gene protects against high-fat diet
... cholesterol and blood vessel plaques exhibited by animals with the normal complement of receptors. Remarkably, in mice fed a normal, balanced diet, the excess receptors worsened blood lipid levels, the researchers reported. The findings suggest that natural variation among individuals in the quantity of th......e in the liver and eliminated fat in the diet, the animals became sick, with livers full of fat." Further study found that, in the absence of new fat, the mice exhibited a marked decline in the activity of genes critical for the metabolism of glucose, fatty acids, and cholesterol. Those genes are normally t...