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Iron Deficiency Sparks Dramatic Changes In Gene Expression

... DennisJ. Thiele, Ph.D., professor of Pharmacology and Cancer Biology at Duke.He said their discovery could aid in the diagnosis and ultimately thetreatment of serious disorders caused by low iron levels.Results of his study, funded ...

Learning to fight an adversary that won't stay down

...resistance. Techniques such as genomic sequencing and high throughput screening were expected to make the development of new antibiotic compounds easier and more productive. But in most cases the microbes continue to hold the upper hand ?and if three billio...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...al Chemistry, an American Society for Biochemistry and Molecular Biology journal. Mycobacterium tubercul...losis has prompted the search for new drug targets and a better understanding of the mechanism of resistance in this bacterium. Several spans of DNA in th...

Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6

... todayannounced the release of GeneLinker(TM) Gold and Platinum 4.6, newversions of the award-winning Gene Expression and Proteomics AnalysisSoftware products."The new releases are focused primarily on importing and analyz...

Novel Enzyme Shows Potential As An Anti-HIV Target

...es in comparison to the 3.2 gigabases of its human and nonhuman primate targets. The compact retrovirus e... play different roles in promoting viral infection and virulence. As a retrovirus, HIV uses the host’s cellular machinery—including RNA polymerases, which ...

Scientists seek answers on what activates deadly anthrax spores

...s at Wake Forest University Baptist Medical Center and three other institutions are setting out to find w...echanism in anthrax is clear, as spore germination and outgrowth are fundamental to proliferation." Claiborne, co-director of Wake Forest's Center for Str...

Found: Missing sequence of the human Y chromosome

... GenomeResearch that they have successfully cloned and characterized apreviously intractable DNA sequence... be implicated insex-associated height differences and gonadal tumor development. Thispericentromeric gap was one of the few holes remaining in the"finish...

U of M researcher examines newly emerging deadly disease

...cells), often leading to death due to hypertension and shock. Purpura fulminans has been identified in fi...meningococcemia or invasive streptococcal disease, and it is typically characterized by the depletion of clotting factors in the blood and skin lesions. Pu...

NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis

...e stages--by preventing the formation of viral RNA and proteins, and blocking the virus' release, which could infect other cells in the brain. "There is no magic bullet...

Study finds more than one-third of human genome regulated by RNA

For many years, DNA and proteins have beenviewed as the real movers and shakers in genomic studies, with RNA seenas little more than a messenger that shuttles information b...

Live Recombinant Adenovirus Vaccine Technique Explored

...enovirus vaccines have long been proven to be safe and effective. The researchers believe their process f...nufacture, require trained personnel to administer and multiple doses to provide immunity, which is not feasible for people living in many parts of the wor...

Marburg virus disease in Angola - update

...nistry of Health has reported a total of 124 cases and 117 deaths in Cabinda, Luanda and Uige. All these cases had originated in Uige Province. Ten of these cases have been laboratory confi...

Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa

...f a retina mircrochip has allowed Emory Eye Center and the Atlanta Veterans Affairs Rehabilitation Resear...en to conduct the expanded trial. Other than Emory and the VA Rehabilitation R&D Center they include Rush University Medical Center's Department of Oph...

The secret lives of whales

Using genetics, Navy sonar, deep-sea submersibles, and toxicology, scientists are peering into the lives of whales ?past and present ?in ways never before possible. At a 3:00 PM press conference on February 19th at the annual...

NYU researchers simulate molecular biological clock

For many years, DNA and proteins have beenviewed as the real movers and shakers in genomic studies, with RNA seenas little more than a messenger that shuttles information b...

Dinosaur DNA? New Patent Covers Degraded DNA recovery

...to Burt D. Ensley, Ph.D, Chairman of MatrixDesign, and CEO of DermaPlus, Inc. The patent covers methods for recovering and reconstituting genes from "degraded" DNA samples, and could allow scientists to reassemble everythin...

Leukemia Drug Breakthrough Study In New England Journal Of Medicine

...od vessels that nourish tumors (anti-angiogenesis) and stimulates the immune system to fight cancer cells...ine. Nearly 90 percent of MDS patients are anemic and require regular transfusions of red cells. In this study, 91 percent of the MDS patients with a chro...

Mitochondrial DNA mutations play significant role in prostate cancer

... scientists at Emory University School of Medicine and theUniversity of California, Irvine. The findings ...John A. Petros, MD, associate professor of urology and pathology atEmory University School of Medicine and the Winship Cancer Institute,and Douglas C. Wall...

Gene therapy converts dead bone graft to new, living tissue

... promising development for the thousands of cancer and trauma patients each year who suffer with fragile and failing bone grafts. The findings were posted online Feb. 13 and will appear in the March 1 issue of...

Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey

... cells (eithernormal body cells or other bacteria) and target them for destruction.Reported in the Decemb...etection?mechanism, should preventtoxin production and limit the severity of infection,?says MichaelGilmore, PhD, lead author of the study, and currently d...

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