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Tag: "analyses" at biology news

Researchers rein in regulatory RNAs

...of the most comprehensive genome-wide experimental analyses of sense-antisense transcripts to date. Their find...iking characteristics. Northern blot hybridization analyses of six randomly chosen SAT pairs revealed that the SAT loci generated multiple transcripts of variou...

Researchers find new genes necessary to make embryo

...s in different individuals. "The results from the analyses of genes showing partial penetrance suggest the possibility of a general architectural motif in genetic networks," said Fabio Piano, an NYU biologist and lead author of the study, "in which genes in critical positions consist largely of older compone...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

... the site of infection with a series of laboratory analyses and mathematical models designed to streamline drug development. The method helps better determine which drugs are worth studying in people and at which dose, avoiding the typically lengthy and expensive trial-and-error approach that can take years. ...

Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert

...tested had bacteria in it." Minkley is conducting analyses to determine the genetic characteristics of the recovered bacteria to identify the different microbial species present in the samples. He also is testing the bacteria's sensitivity to ultraviolet (UV) radiation. One hypothesis is that the bacteria ma...

Fleshing out the genome

...hod that integrates experimental and computational analyses to ascribe function to genes that had been termed ...he microbe when subjected to stress. The proteomic analyses were done by four teams led by Kolker, Carol S. Giometti, Argonne National Laboratory (ANL); John R....

Substance protects resilient staph bacteria

... anthrax." The group used genetic and biochemical analyses to show that PGA is produced in S. epidermidis. They then used three S. epidermidis strains--one natural, one altered to eliminate PGA production and one altered to produce excess PGA--to show that PGA protects S. epidermidis from innate immune defen...

Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients

...—at each time point. The authors used statistical analyses to search for gene expression profiles that were a... therapeutic outcomes. They looked for patterns in analyses of single genes, gene pairs, and gene triplets, and found their model's predictive accuracy increase...

Expression Project for Oncology (expO) completes first phase of standardized gene expression analyses

...er standard conditions and perform gene expression analyses on a clinically annotated set of deidentified tumor samples updated with clinical outcomes and release all data into the public domain without intellectual property restriction. "This publicly accessible gene expression clinical database of patient ...

International HapMap consortium expands mapping effort

...p Project has allowed scientists to make important analyses of the human genome that were not possible with just the human DNA sequence, and the International HapMap Consortium plans to publish its comprehensive analysis of this data later this year. The second phase of the project will provide researchers wi...

Scientists find fossil proof of Egypt's ancient climate

...iewicz, are using stable isotope and minor element analyses of the freshwater gastropod Melanoides tuberculata... conditions during the lifetime of the lake. Their analyses support a surprising picture of arid Egypt: 130,000 years ago, what everyone considers an eternal de...

Family trees of ancient bacteria reveal evolutionary moves

...lfide as an electron donor. "We will need lots of analyses of the micro-fossil record by serious paleobiologists to see how sound this hypothesis is," Blank said. "This time frame is one of the biggest puzzles for biologists and geologists alike. A huge amount of things are happening then in the geological r...

Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance

...g the next five years the projects include genetic analyses and measurement of gene expression in patients with atherosclerosis, breast cancer, rheumatoid arthritis, asthma and dyslexia. These diseases affect a large number of patients worldwide. Systematic use of the genomic information obtained will enable ...

Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra

...ree islands than on fox-infested islands came from analyses of nitrogen isotopes in soil, plant, and animal samples. "The terrestrial ecosystem was being subsidized by marine-derived nutrients, and the foxes basically cut off the subsidies by interrupting the flow of nutrients coming from offshore," Croll sa...

Elephants imitate sounds as a form of social communication

...ronment of the subjects of this study. Spectrogram analyses of the audio frequency of the imitations were nearly perfect matches to the original sounds. Mlaika, a ten-year-old adolescent female African elephant living in Kenya among a group of semi-captive orphans, mimicked noises she heard from trucks on a ...

Elephants imitate truck noises, other animals

...ronment of the subjects of this study. Spectrogram analyses of the audio frequency of the imitations were nearly perfect matches to the original sounds. Mlaika, a ten-year-old adolescent female African elephant living in Kenya among a group of semi-captive orphans, mimicked noises she heard from trucks on a ...

Neuronal 'traffic jam' marks early Alzheimer's disease

...d subsequent neural degeneration. The scientists' analyses of the neurons in those mice revealed clear defects, said Goldstein. "What we saw quite early in the life of those animals -- well before any plaque deposition -- were obvious axonal defects," said Goldstein. "We saw large swellings in their axons. A...

New, automated tool successfully classifies and relates proteins in unprecedented way

...ical sciences at CarnegieMellon. The computational analyses were carried out together with XiangChen, a graduate student in the Merck Computational Biology andChemistry program.Chen and Murphy found that the new tool outperformed existing methodsof identifying overlapping proteins within cells, such as simple...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

...d leaders in thetechnology for large-scale genetic analyses and statistics. The geneticand statistical analyses were performed by the doctoral student SnaevarSigurdsson and Professor Ann-Christine Syvänen at the ...

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