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Tag: "analyses" at biology news

Researchers identify genes in fruitflies that may shed light on human cancer spread

...researchers also hope to perform more whole genome analyses to identify genes that interact with those already known to play a role in cell migration and metastasis. ...

Biologists develop genome-wide map of miRNA-mRNA interactions

...ty of California, Berkeley have used computational analyses to predict a genome-wide map of microRNA (miRNA) targets in the animal model organism, Caenorhabditis elegans (C. elegans). MicroRNAs bind to messenger RNA (mRNA) in a specific section, called 3'UTR, and are known to regulate them. Parts of the predi...

Paleontologists learn how not to become a fossil

...for analyzing other groups. And of course as those analyses begin to accumulate, we'll have a much clearer picture of what's missing from the fossil record and how to make corrections, producing a clearer picture of the biological dynamics of the past." ...

Retinol for combating leukemia cells

...rrow impeding the formation of blood cells. In the analyses undertaken in the laboratory, it was seen that 95 ...m of the retinamide at a molecular level. From the analyses it was observed that the retinamide accelerated the oxidative stress within the malign cells and tha...

New analysis shows three human migrations out of Africa

...ent haplotype trees and performed phylogeographic analyses that reconstructed the history of the species through space and time. Three years later, he had 25 regions to analyze and the data provided molecular evidence of a third migration, this one the oldest, back to 1.9 million years ago. "This time fr...

Potential heart benefit found in stem cells

...lectrical communication between the cells. Further analyses of the cells revealed appropriate cardiac gene expression and action potential, as well as sustained and significant positive cardiac troponin-1, a calcium-regulated protein in muscle tissue, and connexin 43, a protein that assists in intracellular i...

Wound monitor 'sniffs out' infections

...and pattern recognition system, enabling the rapid analyses of molecules in the air. It is envisaged that the monitor will be take the form of a mobile unit which sits alongside other monitoring equipment next to the patient. Key applications for the device will include monitoring trauma injuries, chronic ul...

Predicting chemotherapy outcome

...13 patients with colorectal cancer. The microarray analyses were carried out before the patients were treated with combined chemotherapy of folinic acid, 5-fluorouracil and irinotecan. Imbeaud and colleagues identified 679 genes that were differently expressed in patients who subsequently responded well to c...

Genomics-based vaccine could prevent deadly cattle disease

... subunit vaccine. Based on combined bioinformatics analyses and lab tests, these proteins appear to provide a protective immune response to the disease. "This initiative took just three years, after many years of scientists trying other methods," remarks Vishvanath Nene, a study author and molecular biologist...

Carbon cycle was already disrupted millions of years ago

...erised by a relatively strong increase in 12C. The analyses have shown that this was caused by a sudden large-scale release of carbon from stocks stored in the ocean floor or peats and bogs. The atmospheric carbon dioxide concentration is increasing as a consequence of the large-scale use of fossil fuels in...

UC San Diego partners with Venter Institute to build marine microbial genomics cyberinfrastructure

...alyze families of proteins and conduct comparative analyses across multiple genomes. "Each individual sequence is no longer just a piece of a genome. It is part of an entire biological community," said Peter Arzberger, Ph.D., director of the NIH-funded National Biomedical Computation Resources (NBCR), and le...

Spousal illness can trigger partner death

... women whose husbands were hospitalized. Further analyses also confirmed that the death of a spouse within the past 30 days was harmful. The death of a wife in the previous 30 days increased her husband's risk of death 53 percent, and the death of a husband increased his wife's risk of death by 61 percent....

Engineered mouse mimics cognitive aspects of schizophrenia

...n of a particular odor with a reward. Biochemical analyses of the animals' brains revealed that the excess dopamine receptor activity in the striatum contributed to abnormal prefrontal cortical function. Importantly, found the researchers, they could not reverse these cognitive deficits by using the antibio...

Virginia Tech helping to develop higher quality, disease-resistant wheat varieties

...ing laboratories to provide thousands of molecular analyses required to deploy the targeted genes into breeding lines. The genetic information will be stored in national databases and seed stocks deposited in USDA's Small Grain Collection, providing long-term public access to genetic information and resource...

New compound stops brain cell degeneration in Alzheimer's disease

...n said. "Third, the design, synthesis and in vivo analyses were carried out by a new generation of young scientists trained in our educational program to instruct the next generation of interdisciplinary scientists," Watterson said. Northwestern University patented the compound designated 188WH and has excl...

Heart-healthy compound in chocolate identified

... the same level of cardiovascular health. Through analyses of urine samples from members of both the island-dwelling and mainland Kuna, the researchers found that, compared to their mainland counterparts, the urine of island dwellers had more than twice the levels of urinary nitric oxide -- a chemical compou...

New nano-canary in the nanotoxicology coalmine: The body itself

...teristics are also being constructed to facilitate analyses of variability, reduce uncertainties in animal to human extrapolations and contribute to a more quantitative representation of environment-disease interactions." ...

Largest study of human 'interactome' reveals a novel way

...s in human protein-protein interactions." All the analyses were primarily carried out at the IOB, a nonprofit research institute founded by Pandey in May 2002. The Human Protein Reference Database was developed with funding from the National Institutes of Health and the Institute of Bioinformatics. Pandey ...

UCSD study finds anthrax toxins also harmful to fruit flies

...e study. "What this means is that similar types of analyses might identify yet unknown proteins shared by flies and humans that can be acted on by anthrax toxins. More generally, this study suggests that flies can be used as a rapid whole organism system to determine the function of a variety of bacterial and...

Poison + water = hydrogen. New microbial genome shows how

...quence was determined. By utilizing computational analyses and comparison with the genomes of other organisms, the researchers have discovered several remarkable features. For example, the genome encodes a full suite of genes for making spores, a previously unknown talent of the microbe. Organisms that mak...

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