PET/MRI scans may help unravel mechanisms of prenatal drug damage
...MRI) to track the uptake and distribution of trace amounts of cocaine in pregnant monkeys and found significant differences in where and how fast the drug accumulates in maternal and fetal organs. "Understanding how drugs are transferred between a mother and her fetus during pregnancy may help us unravel th...Dead zone area in Gulf could be increasing, researchers say
...pring flood stage of the rivers, which bring large amounts of nutrients ?often in the form of fertilizer ?into the Gulf of Mexico. The Mississippi is the largest river in the United States, draining 40 percent of the land area of the country. It also accounts for almost 90 percent of the freshwater runoff i...Chemists identify immune system mechanism for methamphetamine binges
...ies to the drug itself, so they require increasing amounts to get high, resulting in binging behavior, he say...requiring more frequent intake and ever-increasing amounts of the drug in order to achieve a high," says Janda, who led the study with his former student, Tobi......ones like estrogen and progesterone can change the amounts of proteins made by their target genes. When hormone binds to receptors inside the cells, they are activated to seek out target genes. They then recruit the coactivators ?in this case CAPERá and CAPERâ. These coactivators not only cause the gene to b...Nanoscale Diagnostic Sets Sights on Alzheimer's
.... The goal is to detect and validate infinitesimal amounts of the biomarkers in blood. Research by Klein and his colleagues suggests that ADDLs first appear in the earliest stages of Alzheimer's. If the BCA process can identify the markers before symptoms develop, doctors may be able to combat the illness i...A human parasite with a streamlined mitochondrion
... cells--including our own--because they make large amounts of energy as they use oxygen. However, some eukaryotic cells, including important parasites of humans--such as Entamoeba histolytica, the causal agent of amoebic dysentery--live in environments that are too oxygen poor to support this process. Nevert...Multi-purpose protein regulates new protein synthesis and immune cell development
...gnaling pathway and directs cells to secrete large amounts of protein. The University of Michigan has filed a...enerating plasma cells. Plasma cells secrete large amounts of protein antibodies into the bloodstream. Antibodies lock on to antigens ?substances that trigger ...Computational Method Speeds Mapping of Cell Signaling Networks
...t-genomic age when researchers are generating vast amounts of data. The statistical approach requires no prio...ing cancer and autoimmunity. Until now, the large amounts of data the technique requires prevented its application to protein networks. Being able to monitor ...Survey finds silver contamination in North Pacific waters
...trial emissions from North America and Europe, the amounts are small compared to what goes into the Pacific from Asia," he said. ...Buying Time Through Hibernation on Demand
...enous infusion of saline solution mixed with trace amounts of an agent that would interfere with the body's ability to use oxygen, Roth said. Using oxygen deprivation to depress metabolic activity also might extend the amount of time that organs and tissues could be preserved outside the body prior to trans...U-M team recovers ancient whale in Egyptian desert
...enous infusion of saline solution mixed with trace amounts of an agent that would interfere with the body's ability to use oxygen, Roth said. Using oxygen deprivation to depress metabolic activity also might extend the amount of time that organs and tissues could be preserved outside the body prior to trans...Love's all in the brain: fMRI study shows strong, lateralized reward, not sex, drive
...ncept is that the caudate probably integrates huge amounts of information, everything from early personal memories to one's personal notions of beauty. Then, this brain region (and related regions of the basal ganglia) helps to direct one's actions toward attaining one's goals. For neuroscientists," she said...NASA study finds snow melt causes large ocean plant blooms
...ental to the ecosystem. Increases in phytoplankton amounts can lead to oxygen depletion in the water column and eventually to a decline in fish populations. The Arabian Sea hosts one of the world's largest pools of oxygen-poor water at depths between 200 and 1,000 meters (656 to 3,281 feet). Since the Arabi...Global analysis of membrane proteins
...., drug development who often need access to large amounts of purified membrane proteins. Large-scale projects where scientists from different fields work together are becoming increasingly common in biology. The new study has been made possible through a close collaboration between biochemists at Stockholm...Turning viruses into allies against cancer
...from patients shows that these cells contain large amounts of the natural receptor for the measles virus, CD46. Overexpression of this receptor thus makes liver cancer cells ideal targets for the measles virus. The results confirmed widespread infectivity, toxicity and destruction among these cells, probably...Road salt affects mitigation wetlands
... two PennDOT-installed data loggers to measure the amounts of salt that enter the designated runoff wetland and one other that is slightly affected by splashover from salt spreading and snow melting. The data loggers record salinity hourly. "Salt levels in the runoff wetland reach peaks that are half as sal...UCLA scientists store materials in cells natural vaults
... thousands of tiny capsules in cells to store vast amounts of biomaterial. Dubbed vaults ?for their high arches reminiscent of cathedral ceilings ?these naturally occurring capsules may prove less likely to elicit an immune response than foreign carriers like viruses. IMPACT: The UCLA discovery will enable ...Study reveals candidate targets for anti-retroviral therapeutics
...gram (GOnet) allowing them to search through large amounts of genetic and biochemical data to identify "clusters," or related groups of genes, that are most likely to affect key points in the Ty3 lifecycle. In total, they identified 130 genes that affect the replication of the retrovirus-like element Ty3. O...Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX
...es in gene expression by reducing the overwhelming amounts of globin messenger RNA (mRNA) present in whole blood. Large amounts of globin mRNA can significantly interfere with gene expression assay results. High globin mRNA leve...To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists
... ability to mutate, even when subjected to massive amounts of ultraviolet light. This brought Romesberg to the conclusion that mutation is a programmed stress response -- a survival mechanism. If the cell senses damage, and if the damage persists beyond its ability to repair it, the cell will turn on its mu...