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Tag: "amino" at biology news

Researchers discover key mechanism by which lethal viruses Ebola and Marburg cause disease

... Marburg, cause disease. The identification of an amino acid sequence in Filoviruses that results in the r..." In the study, researchers describe a series of amino acids in Ebola and Marburg viruses that resemble proteins in retroviruses known to suppress the immu...

New engineered drug may offer prolonged arthritis relief

...teins." As the proteins degrade, they yield simple amino acids, which are the building blocks of all proteins. By experimenting with composition, molecular weight and concentration of various ELPs, Betre developed a protein for use in joints that would precipitate out of solution and clump at normal body...

Engineer ramps up protein production, develops versatile viral spheres

...rst time, but also have attached uniquely reactive amino acids to the capsid surfaces. Theamino acids allow the capsids to either stick to and carry specific proteins orstick to other capsids, allowing their assembly en masse. The tiny spheres could therefore transport targeted vaccines or medicines arou...

Biologists probe the machinery of cellular protein factories

...s to carry out their functions. They are made from amino acid building blocks, and the sequence of amino acids determines the protein's structure. Amino acids are carried to the ribosome by transfer RNA mo...

Motorola researchers develop selective sensors based on carbon nanotubes

...c properties." The peptides are made of 20 or so amino acids, so changing the sequence of amino acids allows the researchers to "tune the peptides and recognize different compounds," Tao said. "We...

Mayo discovers protein as potential tactic to prevent tumors

...ation to a specific serine residue on the chain of amino acids that make up FOXO1. In case of robust errors found in the genetic code, CDK2 signals FOXO1 to explicitly call for the cell to produce a set of proteins leading to apoptosis. "If the cell has minor alterations in the DNA code that can be repa...

Regulating the nuclear architecture of the cell

...thyl groups to the histone labeled H3 at its ninth amino acid residue, which is a lysine. In the histone co... this is by acetylation of the H3 histone's fourth amino acid, also a lysine. The effect is to open the chromatin at that site, making the DNA accessible. ...

MIT material stops bleeding in seconds

...emains sealed. The gel eventually breaks down into amino acids, the building blocks for proteins, which can be used by surrounding cells. The exact mechanism of the solutions' action is still unknown, but the researchers believe the peptides interact with the extracellular matrix surrounding the cells. "...

Detailed 3-D image catches a key regulator of neural stem cell differentiation in action

...sional image showing how Scp1 hangs onto the seven amino acid residues reiterated in the polymerase tail. "...aper's first author. "It turns out that only three amino acids are important for Scp1's ability to know how to remove phosphates from RNA polymerase." S...

Selecting life: Scientists find new way to search for origin of life

... become essential ingredients to all life--such as amino acids (the building blocks of proteins) and nuclei...nd others has shown that many molecules, including amino acids, can adhere to mineral surfaces, prompting further organic reactions. These findings have made...

Clue found to Epstein-Barr virus' ability to form and sustain tumors

... experiments to mutate various segments of the 640 amino acids that make up the EBNA-1 protein, which is on...en into protein. Mutating the unique segment of amino acids prevented EBNA-1 from transforming resting B cells into proliferating cells. Under normal con...

New technique boosts size of proteins that can be analyzed

...n be analyzed, to those containing more than 2,000 amino acids, up from about 500. Called a "top-down" ap...ed, enzymatically into smaller units of five to 20 amino acids. These pieces are then introduced into the mass spectrometer where researchers can match masse...

Common ancestry of bacterium and plants could be key to an effective new treatment for chlamydia

...ystery of how plants produce lysine, one of the 20 amino acids normally found in proteins. Scientists have known the specific pathways of lysine production in bacteria for more than a half-century. They also have known some of the steps by which lysine is produced in plants, but they didn't really have the...

An AIDS-related virus tricks cells to become tumors, new Penn study finds

...to ubiquitin. "We found that the viral LANA has an amino acid motif that mimics non-viral cell proteins usu...rocess," says Robertson. This motif, or stretch of amino acids, normally enables LANA to bind to tumor suppressors p53 or VHL, thus bringing them into the ac...

Comprehensive model is first to map protein folding at atomic level

...great problems in science has been deciphering how amino acid sequence -- a protein's primary structure -- ...al to the chemistry of life. Each of the body's 20 amino acids, the building blocks of proteins, is attracted or repulsed by water; it's largely these affini...

Why don't all moles progress to melanoma?

...duction factory. The process begins when chains of amino acids are deposited in the ER membrane in response...ructions from genes. Chaperone proteins fold these amino acids into specific shapes. When too many of them build up in the membrane, or when something goes w...

Researcher examines polymers created with poultry feathers

...nd strong. Barone has found that altering the amino acid structure of keratin can improve the strength and longevity of the polymer. In addition, the viscosity can be improved with reducing agents such as sodium sulfite and lubricants such as poultry fat. The solid-state properties can also be modifie...

Scientists identify a candidate gene for osteoporosis

...han and his colleagues predict that changes in the amino acid sequence or alterations in regulatory regions of the DARC gene may lead to key functional changes. "There are interesting differences between African Americans and Caucasians that could be associated with this gene," explains Mohan. "Afric...

Non-GMO solution to seafood allergies

...on damages the proteins, revealing hidden reactive amino acid residues. Subsequent heating then destroys the exposed residues. "Radiation and heat seems to be a promising method for reducing the immunoreactivity" say the researchers. Samuel Lehrer of Tulane University in New Orleans, USA, is already wor...

How fish conquered the ocean

...ts yolk protein products to be broken down to free amino acids and thus drive hydration of the maturing eggs. The timing of these events matches the appearance of the vast numbers of marine acanthomorph teleosts in the fossil record. The authors propose that the neo-functionalization of duplicated vitellog...

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